ABSTRACT
Introducción: Las complicaciones cardiacas en pacientes con dengue no son infrecuentes y no son diagnosticadas, ya que usualmente son leves y autolimitadas. Objetivos: Caracterizar las manifestaciones cardiovasculares en pacientes hospitalizados con infección por dengue. Métodos: Se realizó un estudio epidemiológico observacional, analítico, de corte longitudinal, prospectivo, que incluyó 427 pacientes atendidos en el Hospital Docente Clínico-Quirúrgico Comandante Manuel Fajardo con diagnóstico de infección por dengue durante el periodo comprendido desde abril de 2017 hasta abril de 2018. Resultados: Las manifestaciones cardiovasculares (19,7%), principalmente los trastornos del ritmo (bradicardia sinusal [13,8%], extrasístoles auriculares [4,9%] y ventriculares [4,0%]) fueron frecuentes en pacientes con infección por dengue. La pericarditis y miocarditis se identificó en el 1,6% y 0,2%, respectivamente. Estas manifestaciones fueron autolimitadas en el 83,3% y se presentaron en los primeros días de inicio del cuadro febril en el 75,0%. La edad avanzada (OR=1,70), el sexo masculino (OR=1,94), el recuento de plaquetas disminuido (OR=1,13) y el dengue con signos de alarma (OR=3,29) se relacionaron con una mayor probabilidad de presentar manifestaciones cardiovasculares en el curso de una infección por dengue. Conclusiones: Las manifestaciones cardiovasculares en pacientes con dengue son frecuentes, y se relacionan con la edad avanzada, el sexo masculino, así como las formas severas de la enfermedad.(AU)
Introduction: Cardiac complications in dengue patients are not uncommon and are not diagnosed, since they are usually mild and self-limiting. Objectives: To characterize the cardiovascular manifestations in hospitalized patients with dengue infection. Methods: We conducted an observational, analytical, longitudinal, prospective epidemiological study, which included 427 patients treated at Manuel Fajardo Clinical-Surgical Teaching Hospital with diagnosis of dengue infection since April 2017 to April 2018. Results: Cardiovascular manifestations (19.7%), mainly heart rate disorders (sinus bradycardia [13.8%], atrial [4.9%] and ventricular [4.0%] extrasystoles) were frequent in dengue infection patients. Pericarditis and myocarditis were diagnosed in 1.6% and 0.2% respectively. These disorders were self-limiting in 83.3% of cases and occurred in the first days of the onset of fever in 75.0%. Advanced age (OR=1.70), male sex (OR=1.94), decreased platelet count (OR=1.13) and dengue with warning signs (OR=3.29) were related to a higher probability of presenting cardiovascular disorders in the course of a dengue infection. Conclusions: Cardiovascular manifestations in dengue patients are frequent, and are related to advanced age, male sex, as well as severe forms of the disease.(AU)
Subject(s)
Humans , Male , Female , Dengue/complications , Dengue/diagnosis , Dengue/etiology , Cardiovascular Diseases , Bradycardia , Atrial Premature Complexes , Pericarditis , Myocarditis , Microbiology , Communicable Diseases , Cuba , Prospective Studies , Longitudinal StudiesABSTRACT
INTRODUCTION: Cardiac complications in dengue patients are not uncommon and are not diagnosed, since they are usually mild and self-limiting. OBJECTIVES: To characterize the cardiovascular manifestations in hospitalized patients with dengue infection. METHODS: We conducted an observational, analytical, longitudinal, prospective epidemiological study, which included 427 patients treated at Manuel Fajardo Clinical-Surgical Teaching Hospital with diagnosis of dengue infection since April 2017 to April 2018. RESULTS: Cardiovascular manifestations (19.7%), mainly heart rate disorders (sinus bradycardia [13.8%], atrial [4.9%] and ventricular [4.0%] extrasystoles) were frequent in dengue infection patients. Pericarditis and myocarditis were diagnosed in 1.6% and 0.2% respectively. These disorders were self-limiting in 83.3% of cases and occurred in the first days of the onset of fever in 75.0%. Advanced age (OR=1.70), male sex (OR=1.94), decreased platelet count (OR=1.13) and dengue with warning signs (OR=3.29) were related to a higher probability of presenting cardiovascular disorders in the course of a dengue infection. CONCLUSIONS: Cardiovascular manifestations in dengue patients are frequent, and are related to advanced age, male sex, as well as severe forms of the disease.
