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An Esp Pediatr ; 44(5): 456-60, 1996 May.
Article in Spanish | MEDLINE | ID: mdl-8796956

ABSTRACT

The aim of this study was to assess the clinical outcome of two different durations of triple therapy in children with Helicobacter pylori infection. We established two treatment groups: 1) Short treatment, including 2 week of bismuth subcitrate, amoxycillin and metronidazole treatment (n = 21) and 2) Long treatment, which included the same therapy for two weeks plus bismuth subcitrate alone for two weeks more (n = 26). We found no difference between the short and long treatments. The infection remained in 14% and 19%, respectively. In both groups, we observed children (19%) with persistent abdominal pain in spite of Helicobacter pylori eradication and gastritis healing. We conclude that it is not necessary to prolong triple therapy more than 2 weeks in order to have therapeutic success.


Subject(s)
Duodenitis/drug therapy , Gastritis/drug therapy , Helicobacter Infections/drug therapy , Helicobacter pylori , Adolescent , Amoxicillin/administration & dosage , Anti-Bacterial Agents/administration & dosage , Bismuth/administration & dosage , Child , Child, Preschool , Drug Evaluation , Drug Therapy, Combination , Female , Humans , Male , Metronidazole/administration & dosage , Organometallic Compounds/administration & dosage , Penicillins/administration & dosage , Time Factors
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