Subject(s)
Antibodies, Monoclonal, Humanized/therapeutic use , Dermatitis, Atopic/drug therapy , HIV Infections/complications , Antibodies, Monoclonal, Humanized/administration & dosage , Dermatitis, Atopic/pathology , Female , Follow-Up Studies , Humans , Middle Aged , Quality of Life , Safety , Treatment OutcomeSubject(s)
Antibodies, Monoclonal, Humanized/therapeutic use , Betacoronavirus/isolation & purification , Coronavirus Infections/complications , Dermatitis, Atopic/drug therapy , Interleukin-4 Receptor alpha Subunit/immunology , Pneumonia, Viral/complications , Adult , Antibodies, Monoclonal, Humanized/adverse effects , COVID-19 , Coronavirus Infections/virology , Dermatitis, Atopic/complications , Female , Humans , Male , Middle Aged , Pandemics , Pneumonia, Viral/virology , SARS-CoV-2ABSTRACT
BACKGROUND: Soft tissue defects are mostly managed surgically by free microvascular flaps. The progressive development of techniques and the availability and reliability of new different and free flaps encouraged this surgical approach. Thus, there is a constant need of free flap models to reproduce in laboratory. The experience with the use of the epigastric free flap in the rat as a laboratory model for microsurgical trainees is presented. In our microsurgical flap model the anastomoses were constantly performed on the femoral vessels. METHODS: The flap was used in 25 rats during the practical sessions of periodical experimental microsurgery courses. The main steps were: flap harvesting on the superficial epigastric vessels; flap anastomosis on the femoral vessels; pedicle section; microvascular anastomosis. RESULTS: The epigastric free flap showed to be an easy surgical model. The mean duration of the exercise was 2 hours and 11 minutes. These surgical times were considered acceptable to the requirement of a laboratory model. CONCLUSIONS: The epigastric free flap in the rat is a reproducible experimental model which is still up to date in microsurgical training.
Subject(s)
Microcirculation/surgery , Microsurgery , Surgical Flaps , Anastomosis, Surgical , Animals , Education, Medical, Graduate , Epigastric Arteries , Microsurgery/education , Rats , Time FactorsABSTRACT
El presente trabajo intento investigar la hipotesis de la irregularidad sobre la genesis de los trastornos psicosomaticos y mas especificamente sus relaciones con la aparicion de las cefaleas. Para este proposito se utilizaron 50 sujetos del sexo femenino, 25 con trastornos cefalgicos y 25 normales como controles. Ambos grupos fueron sometidos a las primeras cuatro fases del perfil psicofisiologico (PPF), utilizandose como parametros de medida, la respuesta electrodermica, la respuesta electromuscular y la temperatura periferica. Para analizar los resultados de ambos grupos se utilizo la T de Student, encontrandose una mayor capacidad de autoregulacion en el grupo de los sujetos normales en relacion con los sujetos cefalgicos en cada una de las fases del PPF a un nivel e significacion de 0.0l, siendo estos datos una primera prueba experimental de la hipotesis de la irregularidad de la cefalea
