ABSTRACT
Femoral regional perfusions and continuous intraarterial infusions were used for the treatment of 84 patients. The 0,15-0,25% solution of H2O2 was used as the oxygenator. The methods used when combined with sympathectomy allowed to restrict the operation by a parcimonious amputation of the extremity and to retain the knee joint in most of the patients.
Subject(s)
Arteriosclerosis Obliterans/therapy , Endarteritis/therapy , Hydrogen Peroxide/administration & dosage , Leg/blood supply , Adult , Aged , Amputation, Surgical/methods , Animals , Cats , Combined Modality Therapy , Dogs , Femoral Artery , Humans , Infusions, Intra-Arterial , Leg/surgery , Lumbosacral Region/innervation , Male , Middle Aged , Rabbits , Sympathectomy/methodsABSTRACT
An original technique developed by the authors was used in 51 experiments on dogs. Under study were the ECG-dynamics, the volume of the retrograde bloodflow and blood pressure in the splenic and anterior interventricular arteries before and after creating the retrograde spleno-coronary anastomosis. The results of studies of hemodynamics at this operation have confirmed its physiological adequacy.
Subject(s)
Coronary Vessels/surgery , Myocardial Revascularization/methods , Splenic Artery/surgery , Animals , Blood Flow Velocity , Blood Pressure , Dogs , Electrocardiography , Heart/physiologyABSTRACT
In search of new sources for cardiac revascularization of the myocardium in ischemic heart disease the authors elaborated experimentally on dogs an operation of construction of retrograde arterial splenocoronary anastomosis. The results of the operation were estimated by means of EEG findings, vital and postmortem coronarography and histological studies of the myocardium and zone of the anastomosis. An analysis of the experimental data obtained has revealed a patency of the vascular anastomosis in most animals; electrocardiographic signs of acute myocardial infarction, developed in high ligation of the anterior intraventricular branch of the left coronary artery, would undergo a prompt reverse dynamics after constructing a splenocoronary anastomosis. Further studies of the mentioned method of revascularization of the myocardium seems to be rather perspective.
