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1.
Rev. bras. otorrinolaringol ; 71(5): 604-608, set.-out. 2005. tab
Article in Portuguese | LILACS | ID: lil-423574

ABSTRACT

O advento dos inibidores de protease, aumentando a sobrevida dos pacientes infectados com HIV aumentou a procura destes pacientes por médicos otorrinolaringologistas, já que 40 por cento a 70 por cento deles podem apresentar alguma alteração otorrinolaringológica. OBJETIVIVOS: Objetivamos, nesse estudo, comparar os achados radiológicos e sintomatologia nasossinusal entre pacientes infectados com HIV e pacientes com AIDS, com rinossinusite crônica. A literatura sobre o assunto é revisada e discutida. FORMA DE ESTUDO: clínico prospectivo com coorte transversal. CASUíSTICA E MÉTODOS: Prospectivamente, 39 pacientes em uso de drogas antiretrovirais foram divididos em 2 grupos: pacientes com diagnóstico de AIDS (grupo I) e aqueles apenas infectados pelo HIV (grupo II). Estes grupos foram comparados clinicamente, quanto à contagem de células CD4+ e avaliação tomográfica dos seios paranasais. RESULTADOS: Os pacientes dos grupos I e II apresentaram média de células CD4+ de 118 cél/10-9l e 377 cél/10-9l, respectivamente. Na comparação dos achados tomográficos pelo sistema de Lund e Mackay, o grupo I apresentou escore médio de 12 e o grupo II apresentou média de escore de 5,63 (p<0,001), sendo a febre e a secreção pós-nasal mais prevalente no grupo I (p<0,001). CONCLUSÃO: A prevalência da sinusite crônica nos pacientes infectados pelo HIV foi de 12 por cento. Os sintomas da rinossinusite foram similares nos pacientes sem AIDS e com AIDS, com exceção da presença de febre. Os pacientes com AIDS apresentaram alterações radiológicas mais extensas do que os pacientes HIV positivos.


Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Adult , Middle Aged , HIV Infections , Rhinitis , Sinusitis , Chronic Disease , HIV Infections/complications , Prospective Studies , Rhinitis/etiology , Acquired Immunodeficiency Syndrome/complications , Acquired Immunodeficiency Syndrome , Sinusitis/etiology , Tomography, X-Ray Computed
2.
Braz J Otorhinolaryngol ; 71(5): 604-8, 2005.
Article in English | MEDLINE | ID: mdl-16612521

ABSTRACT

UNLABELLED: The advent of protease inhibitors, which enhances the survival rate of HIV-infected individuals, leads patients to search for otorhinolaryngologists, as 40-70% of them may present some sort of otorhinolaryngological disorder. AIM: We aimed at comparing the CT scan findings and the nasosinusal complaints of HIV-infected and AIDS patients with clinical diagnosis of chronic rhinosinusitis. The literature on the subject is revised and discussed. STUDY DESIGN: Clinical prospective with transversal cohort. MATERIAL AND METHODS: Prospectively, 39 patients with chronic rhinosinusitis, in use of antiretroviral therapy, were included in the present study and divided into two groups: patients with diagnosis of AIDS (group I) and those infected by HIV (group II). Clinical and laboratorial assessments, with CD4+ cell count and CT evaluation, were performed and compared among groups I and II. RESULTS: Group I and II presented mean CD4+ cell count of 118 cells/10-9l and 377 cells/10-9l, respectively. Comparison of the tomographic findings by the Lund-Mackay staging system presented a score of 12 for group I and 5.63 (pd" 0.001) for group II. Fever and postnasal discharge were more prevalent in group I (pd" 0.001). CONCLUSIONS: In our Service, prevalence of chronic rhinosinusitis in HIV-infected patients was 12%. AIDS patients had a higher incidence of fever and postnasal discharge than those of group II. Moreover, extensive radiological findings were prevalent in patients with AIDS (group I) than in HIV-infected individuals (group II).


Subject(s)
HIV Infections/diagnostic imaging , Rhinitis/diagnostic imaging , Sinusitis/diagnostic imaging , Acquired Immunodeficiency Syndrome/complications , Acquired Immunodeficiency Syndrome/diagnostic imaging , Adolescent , Adult , Child , Child, Preschool , Chronic Disease , Female , HIV Infections/complications , Humans , Male , Middle Aged , Prospective Studies , Rhinitis/etiology , Sinusitis/etiology , Tomography, X-Ray Computed
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