ABSTRACT
INTRODUCTION: Barrett's esophagus (BE) is the main precursor of esophageal adenocarcinoma (EAC). This study aimed to identify the risk factors associated with BE progression to dysplasia or EAC in a Latin population. METHODS: The study is a retrospective analysis of a single-center cohort of patients with BE, evaluated from 2002 to 2012. RESULTS: We identified 420 patients with BE; 281 (66.9%) of them were men with a mean age of 57.2 ± 15.3 years. Among all BE patients evaluated, 81 (19.3%) had progression to some degree of dysplasia/EAC. The mean follow-up was 5.6 years. Multivariate analysis showed that age (OR = 1.03), cigarette smoking (OR = 3.05), long-segment BE (OR = 4.81), and a visible lesion on BE (OR = 6.94) were associated with progression to dysplasia/EAC. CONCLUSION: In Latin patients with BE, age, cigarette smoking, long-segment BE, and the presence of lesions were associated with the presence of dysplasia/EAC.
ABSTRACT
No disponible
Subject(s)
Humans , Female , Middle Aged , Pneumatosis Cystoides Intestinalis/complications , Pneumatosis Cystoides Intestinalis/surgery , Pneumatosis Cystoides Intestinalis , Biopsy/methods , Colonoscopy/methods , Tomography, Emission-Computed/instrumentation , Tomography, Emission-Computed/methods , Tomography, Emission-Computed , Abdomen/pathology , Abdomen , Intestinal Obstruction/complicationsABSTRACT
INTRODUCTION AND AIM: Endoscopic treatment is the best option for patients with postsurgical stricture of main biliary duct. There is scarce information about the incidence of post-endoscopic retrograde cholangiopancreatography (ERCP) complications in this condition. The aim was to evaluate the incidence of complications and the associated risk factors in patients undergoing ERCP for postcholecystectomy biliary stricture. MATERIALS AND METHODS: Prospective analysis of patients with postsurgical stenosis of main biliary duct was carried out. Rate of post-ERCP complications was determined and the associated risk factors were analyzed. RESULTS: A total of 25 patients were included. The success rate of endoscopic treatment was 92% (n=23). Two patients had recurrence of stricture with median follow-up of 23 months (range, 0.3 to 65.4 mo). Five patients (20%) developed acute pancreatitis after ERCP. No risk factors were detected in multivariate analysis. CONCLUSION: Incidence of post-ERCP pancreatitis is high in patients with biliary stricture associated with surgical procedures.
