[An assessment of liver function in victims as a result of the accident at the Chernobyl Atomic Electric Power Station]. / Otsenka funktsional'nogo sostoianiia pecheni u lits, postradavshikh v resul'tate avarii na ChAES.

A total of 254 Kievites of both sexes 19 to 35 years old were examined over 1987-1990. Revealed in the above population were alterations of the functional state of the liver characterizing the amino acid, lipid, and nucleotide metabolisms and suggesting impaired permeability of hepatocytic membranes, inadequate energy security of hepatic cells, and indicating the intrahepatic circulation state and bodily immune reactivity.

[Homeostatic indices in persons subjected to ionizing radiation exposure]. / Nekotorye pokazateli gomeostaza u lits, podvergshikhsia vozdeistviiu ioniziruiushchego izlucheniia.

Over the period of 1986-1990 a comprehensive evaluation was carried out in a series of a 5578 subjects exposed to ionizing radiation because of Chernobyl NPP breakdown, using hematologic, immunologic and biochemical methods of investigation. The above series included liquidators of aftermath of the accident, residents of Pripyat' and Kiev. Changes were revealed in all the parameters studied. In view of the abnormal changes in the values for blood, immunologic status and biochemical tests characterizing the functional state of the liver in those subjects having been in the area of abnormal radiation, as well as its potential remote sequelae, it is advisable that the above contingents of the population be under prophylactic management.

[The results of studies of the peripheral blood from children in Polesie District, Kiev Province and in the city of Kiev 4 years after the accident at the Chernobyl Atomic Electric Power Station]. / Rezul'taty issledovanii perifericheskoi krovi detei Polesskogo raiona Kievskoi oblasti i g. Kieva cherez chetyre goda posle avarii na Chernobyl'skoi AES.

The peripheral blood of 2200 children (age: from 2 to 16 years) inhabiting the Polessye District of Kiev Province and the city of Kiev 4 years after the Chernobyl atomic station accident was studied. An analysis of results revealed the presence of hematologic changes that may be interpreted as sequels of the effect of ionizing radiation on the body, while other changes may be considered as reactive and may in most cases accompany different somatic diseases of infectious-inflammatory character.

[Acute leukemia in middle-aged and elderly people]. / Ostryi leikoz u lits pozhilogo i starcheskogo vozrasta.

A total of 98 acute leukemia patients were investigated and 336 case histories were analyzed. All the patients were divided into 5 groups according to their age. Clinicohematological picture of acute leukemia in middle-aged and senile subjects was characterized by low leukemic infiltration of the bone marrow and more pronounced suppression of normal hemopoiesis.

[The immunological indices of patients with chronic myeloleukemia at the blast crisis stage]. / Nekotorye immunologicheskie pokazateli u bol'nykh khronicheskim mieloleikozom v stadii blastnogo kriza.

Twenty patients with chronic myeloleucosis in the stage of blast crisis were examined. Results of immunological investigations indicate that these patients showed below normal indices of the absorptive and bactericidal function of polymorphous-nuclear neutrophils and cationic proteins. The number of T- and B-lymphocytes was also reduced. The immunity values were to the same degree inhibited as in patients with acute leucosis. Changes of the immune status depend on the degree of blastemia. Along with cytostatic agents patients with chronic myeloleucosis in the stage of blast crisis should undergo immunocorrection, primarily correction of cellular immunity.

[Extracorporeal detoxification (hemosorption, plasmapheresis and plasma exchange) in the intensive therapy of hemolytic disorders]. / Ekstrakorporal'naia detoksikatsiia (gemosorpbtsiia, plazmaferez i plazmoobmen) v intensivnoi terapii gemoliticheskikh sostoianii.

Extracorporeal detoxication techniques (hemosorption, plasmapheresis and plasma exchange) were used in a complex therapy of 55 patients with hemolytic disorders of different etiology. The results of clinical and laboratory studies confirm the efficacy of plasmapheresis. Skin surfaces and mucosa became less icteric, the size of the spleen and liver diminished, the levels of free hemoglobin, bilirubin and circulating immune complexes decreased, blood toxicity reduced. Unlike hemosorption, plasmapheresis and plasma exchange had no unfavourable effects on blood cells.