ABSTRACT
This article presents the results of monitoring in a group of children with severe forms of acute respiratory viral infection and toxic encephalopathy. Hemorheological disorder in the form of hyperviscosity syndrome has been detected in all patients with severe forms of acute respiratory viral infection. It was suggested the inclusion of cytoflavin in the complex therapy for correcting the hemorheological status. The administration of cytoflavin led to reduction of erythrocyte aggregation and general improvements in rheological indices of children with severe forms of acute respiratory viral infection and toxic encephalopathy.
Subject(s)
Blood Viscosity/drug effects , Erythrocyte Aggregation/drug effects , Flavin Mononucleotide/administration & dosage , Inosine Diphosphate/administration & dosage , Niacinamide/administration & dosage , Respiratory Tract Infections , Succinates/administration & dosage , Virus Diseases , Acute Disease , Child , Child, Preschool , Drug Combinations , Female , Humans , Infant , Male , Neurotoxicity Syndromes/blood , Neurotoxicity Syndromes/drug therapy , Respiratory Tract Infections/blood , Respiratory Tract Infections/drug therapy , Virus Diseases/blood , Virus Diseases/drug therapyABSTRACT
Clinical and laboratory indices of intoxication and hemorheology disorders that arise during acute viral infection in children have been studied. It is established for the first time that reamberine is capable of reducing the plasma and blood viscosity and can be used in the program of infusion therapy of high blood viscosity syndrome in children with acute respiratory viral infections. One of the positive mechanisms of reamberin clinical performance is its positive impact on microcirculation and hemorheology. Thus, reamberin can be considered as a means of pathogenetic therapy in acute period of infectious toxicosis during acute respiratory viral infections in children.
