ABSTRACT
Autoimmune encephalitis (AE) is a group of disorders characterized by a wide clinical spectrum ranging from the typical limbic encephalitis to more complex neuropsychiatric symptoms including abnormal movements, psychosis, deficits in memory and cognition, dysautonomia, seizures, or coma. Psychiatric symptoms can occur early in the disease progress or manifest during its course. These symptoms are challenging and often slow down the diagnosis of AE. This is a crucial aspect considering that early diagnosis and management of AE are critical for a good outcome. However, there is a lack in studies outlining the exact symptomatology and specific appropriate care that would allow clinicians to achieve an early diagnosis and management. Additionally, AE in children mostly presents with neuropsychiatric symptoms and diagnosis is especially challenging in kids because of their limited capacity in describing their symptoms, the normal childhood behavioral changes and the possibility of a comorbid psychiatric diagnosis. We present a complex case of seronegative AE with comorbid ADHD (Attention Deficit Hyperactivity Disorder) and anxiety in a young six-year-old girl.
ABSTRACT
A study was carried out on the effect of the shape of impulses used in electroanalgesia on the reduction of tothache sensation. The measurements were done in 46 subjects and it was observed that the relative increment of ocurrent voltage producing pain of tooth 13 was after 10 minutes of electroanalgesia with rectangular impulses: P1 = (142.2 +/- 6.8)%, sinusoidal impulses: P2 = (80.6 +/- 6.3)%, and serrate impulses: P3 = (51.0 +/- 4.6)% in relation to the voltage causing pain of the same tooth before electroanalgesia. The mean age of the studied patients: 23.8 +/- 0.3 years. The greatest effect was obtained using rectangular impulses.
