C-reactive protein-complement factor H axis as a biomarker of activity in early and intermediate age-related macular degeneration.

Purpose: To determine and compare the serum levels of complement Factor H (FH), monomeric C-Reactive Protein (mCRP) and pentameric C-Reactive protein (pCRP) in patients with age-related macular degeneration (AMD) and to correlate them with clinical, structural and functional parameters. Methods: Cross-sectional observational study. One hundred thirty-nine individuals (88 patients and 51 healthy controls) from two referral centers were included and classified into three groups: early or intermediate AMD (n=33), advanced AMD (n=55), and age and sex matched healthy controls (n=51). Serum levels of FH, mCRP, and pCRP were determined and correlated with clinical and imaging parameters. Results: Patients with intermediate AMD presented FH levels significantly lower than controls [186.5 (72.1-931.8) µg/mL vs 415.2 (106.1-1962.2) µg/mL; p=0.039] and FH levels <200 µg/mL were associated with the presence of drusen and pigmentary changes in the fundoscopy (p=0.002). While no differences were observed in pCRP and mCRP levels, and mCRP was only detected in less than 15% of the included participants, women had a significantly higher detection rate of mCRP than men (21.0% vs. 3.8%, p=0.045). In addition, the ratio mCRP/FH (log) was significantly lower in the control group compared to intermediate AMD (p=0.031). Visual acuity (p<0.001), macular volume (p<0.001), and foveal thickness (p=0.034) were significantly lower in the advanced AMD group, and choroidal thickness was significantly lower in advanced AMD compared to early/intermediate AMD (p=0.023). Conclusion: Intermediate AMD was associated in our cohort with decreased serum FH levels together with increased serum mCRP/FH ratio. All these objective serum biomarkers may suggest an underlying systemic inflammatory process in early/intermediate AMD patients.

Techno-economic assessment of microalgae production, harvesting and drying for food, feed, cosmetics, and agriculture.

The objective of this techno-economic analysis is to define the costs for an industrial microalgae production process, comparing different operation strategies (Nannochloropsis oceanica cultivation during the whole year or cultivation of two species, where Phaeodactylum tricornutum and Tisochrysis lutea alternate), production scales (1 and 10 ha), harvesting technologies (centrifugation or ultrafiltration) and drying methods (freeze-drying or spray drying). This study is based on an industrial scale process established in the south of Portugal. The strategy of cultivating N. oceanica all year round is more attractive from an economic perspective, with production costs of 53.32 €/kg DW and a productivity of 27.61 t/y for a scale of 1 ha, a 49.31% lower cost and two-fold productivity than species alternation culture strategy. These results are for biomass harvested by centrifugation (10.65% biomass cost) and freeze-drying (20.15% biomass cost). These costs could be reduced by 7.03% using a combination of ultrafiltration and spray drying, up to 17.99% if expanded to 10 ha and 10.92% if fertilisers were used instead of commercial nutrient solutions. The study shows potentially competitive costs for functional foods, food, and feed additives, specialised aquaculture products (live feed enrichment) and other high value applications (e.g., cosmetics).

Cuidado espiritual durante la pandemia por COVID-19 / Spiritual care during the COVID-19 pandemic

No disponible

Access to healthcare among Chinese immigrants living in Seville, Spain / Acceso a los servicios de salud en población inmigrante china residente en Sevilla, España

Objective: To investigate the use of healthcare services and factors associated with accessing them among Chinese immigrants living in Southern Spain. Method: A mixed methodology was used. A cross-sectional survey was first administered to Chinese immigrants (n=133), and they were asked about their visits to the doctor, use of emergency services, and hospitalization. A phenomenological approach was then used with key informants (n=7). In the interviews, additional information, such as barriers and facilitators to improving accessibility, was explored. Results: In the previous year, 51% had visited a doctor and 34% had visited an Emergency Department. The main reasons for hospitalization were pregnancy (37.5%) and surgery (25%). At least 20% of the sample reported having never visited a doctor. Language difficulties and time constraints were identified as important barriers to accessibility. Sex differences were found among the reasons for lack of time, which, in men, were related to work (odds ratio [OR]=7.7) and, in women, were related to childcare (OR=12). The majority of Chinese immigrants preferred to use Traditional Chinese Medicine as their first treatment rather than visiting a doctor. Conclusions: A lower use of health services was found among Chinese immigrants in Spain compared to the native population. When using health services, they choose acute care settings. Communication and waiting times are highlighted as major barriers. Adapting these demands to the healthcare system may help immigrants to trust their healthcare providers, thus increasing their use of health services and improving their treatment. (AU)

Objetivo: Investigar el uso y los factores asociados al acceso a los servicios de salud en inmigrantes chinos residentes en el sur de España. Método: Se utilizó una metodología mixta. Primero se administró una encuesta transversal a inmigrantes chinos (n=133). Se les preguntó sobre sus visitas al médico y el uso de servicios de emergencia y de hospitalización. Luego se utilizó un enfoque fenomenológico con informantes clave (n=7), explorando información adicional, como barreras y facilitadores para mejorar la accesibilidad. Resultados: El último año, el 51% había visitado al médico y el 34% un servicio de urgencias. La hospitalización se debió principalmente a embarazo (37,5%) y cirugía (25%). El 20% informó que nunca había visitado al médico. Las dificultades de lenguaje y las limitaciones de tiempo fueron barreras importantes para la accesibilidad. Se encontraron diferencias de sexo para la falta de tiempo; en hombres se relacionaron con el trabajo (odds ratio [OR]=7,7) y en mujeres con el cuidado infantil (OR=12). La mayoría prefirió usar medicina tradicional china como primer tratamiento en lugar de visitar al médico. Conclusiones: Se encontró un menor uso de los servicios de salud entre los inmigrantes chinos en España en comparación con la población autóctona. Al utilizar los servicios de salud, eligen los cuidados agudos. La comunicación y los tiempos de espera destacan como barreras principales. Adaptar estas demandas al sistema de salud puede ayudarles a confiar en sus proveedores de atención médica, aumentando el uso de los servicios de salud y mejorando su tratamiento. (AU)

Cuidados enfermeros para el abordaje de la salud comunitaria en población indígena de la Amazonia peruana / Nursing care to address community health of the indigenous population in the Peruvian Amazon

La comunidad nativa Shonori la componen familias asháninkas de la Amazonia peruana. Este trabajo aborda la salud comunitaria mediante una valoración y plan de cuidados de enfermería basado en el modelo de competencia cultural de Purnell y la taxonomía estandarizada enfermera (NANDA, NIC, NOC). La valoración se sustenta en 12 dominios relacionados con la herencia y ecología biocultural, comunicación, roles y organización familiar, conductas de riesgo, nutrición, embarazo, rituales de muerte y espiritualidad y prácticas y proveedores de cuidados de salud. Se detecta como diagnóstico una «salud deficiente de la comunidad relacionada con recursos insuficientes y manifestada por problemas de salud padecidos por la comunidad». Los criterios de resultados esperados en el plan de cuidados son: competencia social, estado de salud de la comunidad y control del riesgo social relacionado con las enfermedades transmisibles. Las intervenciones consisten en fomentar la salud comunitaria, analizar e identificar la situación de salud y riesgos, y controlar y proteger de enfermedades transmisibles y de riesgos ambientales. Intervenciones de la red pública de abastecimiento de agua y subvenciones para el apoyo agrícola y a las viviendas permitieron disminuir vectores, sufragar gastos del abastecimiento de agua segura y comprar alimentos para mejorar la nutrición infantil. El uso de la medicina tradicional fue potenciado y se desarrollaron campañas de salud y educación sexual en coordinación con el sistema oficial de salud. Se hizo un seguimiento durante 40 días, que corroboró la mejora de la salud comunitaria y la necesidad de un abordaje grupal con todos los actores

The native community Shonori is made up of Ashaninka families of the Peruvian Amazon. This paper addresses community health through an assessment and nursing care plan based on the Purnell cultural competency model and the standardized nurse taxonomy (NANDA, NIC, NOC). The assessment is based on 12 domains related to inheritance and biocultural ecology, communication, roles and family organization, risk behaviours, nutrition, pregnancy, death and spirituality rituals, and health care providers and practices. A diagnosis of «Poor health of the community r /t insufficient resources m/b health problems suffered by the community» is detected. The expected results criteria in the care plan are: social competence, community health status and control of social risk related to communicable diseases. The interventions consist of promoting community health, analyzing and identifying the health situation and risks, and controlling and protecting from communicable diseases and environmental risks. Interventions of the public water supply network and subsidies for agricultural and housing support, allowed vectors to be reduced, costs of safe water supply to be covered, and food to be bought to improve child nutrition. The use of traditional medicine was enhanced and health and sexual education campaigns were carried out in coordination with the official health system. A follow-up was carried out for 40 days, corroborating the improvement of community health, and the need for a group approach with all actors

Access to healthcare among Chinese immigrants living in Seville, Spain.

OBJECTIVE: To investigate the use of healthcare services and factors associated with accessing them among Chinese immigrants living in Southern Spain. METHOD: A mixed methodology was used. A cross-sectional survey was first administered to Chinese immigrants (n=133), and they were asked about their visits to the doctor, use of emergency services, and hospitalization. A phenomenological approach was then used with key informants (n=7). In the interviews, additional information, such as barriers and facilitators to improving accessibility, was explored. RESULTS: In the previous year, 51% had visited a doctor and 34% had visited an Emergency Department. The main reasons for hospitalization were pregnancy (37.5%) and surgery (25%). At least 20% of the sample reported having never visited a doctor. Language difficulties and time constraints were identified as important barriers to accessibility. Sex differences were found among the reasons for lack of time, which, in men, were related to work (odds ratio [OR]=7.7) and, in women, were related to childcare (OR=12). The majority of Chinese immigrants preferred to use Traditional Chinese Medicine as their first treatment rather than visiting a doctor. CONCLUSIONS: A lower use of health services was found among Chinese immigrants in Spain compared to the native population. When using health services, they choose acute care settings. Communication and waiting times are highlighted as major barriers. Adapting these demands to the healthcare system may help immigrants to trust their healthcare providers, thus increasing their use of health services and improving their treatment.

Nursing care to address community health of the indigenous population in the Peruvian Amazon. / Cuidados enfermeros para el abordaje de la salud comunitaria en población indígena de la Amazonia peruana.

The native community Shonori is made up of Ashaninka families of the Peruvian Amazon. This paper addresses community health through an assessment and nursing care plan based on the Purnell cultural competency model and the standardized nurse taxonomy (NANDA, NIC, NOC). The assessment is based on 12 domains related to inheritance and biocultural ecology, communication, roles and family organization, risk behaviours, nutrition, pregnancy, death and spirituality rituals, and health care providers and practices. A diagnosis of «Poor health of the community r /t insufficient resources m/b health problems suffered by the community¼ is detected. The expected results criteria in the care plan are: social competence, community health status and control of social risk related to communicable diseases. The interventions consist of promoting community health, analyzing and identifying the health situation and risks, and controlling and protecting from communicable diseases and environmental risks. Interventions of the public water supply network and subsidies for agricultural and housing support, allowed vectors to be reduced, costs of safe water supply to be covered, and food to be bought to improve child nutrition. The use of traditional medicine was enhanced and health and sexual education campaigns were carried out in coordination with the official health system. A follow-up was carried out for 40 days, corroborating the improvement of community health, and the need for a group approach with all actors.

New Opportunities for Endometrial Health by Modifying Uterine Microbial Composition: Present or Future?

Current knowledge suggests that the uterus harbours its own microbiota, where the microbes could influence the uterine functions in health and disease; however, the core uterine microbial composition and the host-microbial relationships remain to be fully elucidated. Different studies are indicating, based on next-generation sequencing techniques, that microbial dysbiosis could be associated with several gynaecological disorders, such as endometriosis, chronic endometritis, dysfunctional menstrual bleeding, endometrial cancer, and infertility. Treatments using antibiotics and probiotics and/or prebiotics for endometrial microbial dysbiosis are being applied. Nevertheless there is no unified protocol for assessing the endometrial dysbiosis and no optimal treatment protocol for the established dysbiosis. With this review we outline the microbes (mostly bacteria) identified in the endometrial microbiome studies, the current treatments offered for bacterial dysbiosis in the clinical setting, and the future possibilities such as pro- and prebiotics and microbial transplants for modifying uterine microbial composition.

Long-Term Intravitreal Dexamethasone Implant Outcomes in Uveitis.

Purpose: To describe the long-term clinical outcomes in a cohort of uveitic eyes treated with the intravitreal dexamethasone implant (Ozurdex; Allergan, Inc).Methods: Seventy-nine (63 patients) receiving 134 implant injections over 82 months were included. Indication, visual acuity (VA), intraocular pressure (IOP), vitreous haze score (VHS), central retinal thickness (CRT), time to reinjection, systemic treatments, and complications data were recorded.Results: The cumulative probability of VA improvement was 80% at 1 month and 90% at 12 months, and it was maintained until 60 months. Eyes with baseline vitritis (VHS >0.5; 68%) had a probability of VHS improvement of 33% at 1 month, 75% at 12 months, and 85% at 60 months. The probability of CRT improvement was 33% at 1 month, 75% at 12 months, and 85% at 60 months. The most frequent adverse event was moderate IOP elevation (≥25 mmHg) in 30.3%, no cases of retinal detachment or endophthalmitis were observed.Conclusions: The dexamethasone implant provides favorable VA, CRT, and VHS long-term outcomes in uveitis with a reduced rate of severe adverse events.

Opinions, Knowledge and Attitudes Concerning "Spirituality, Religiosity and Health" Among Health Graduates in a Spanish University.

This study aims to investigate the opinions, knowledge and attitudes concerning spirituality, religiosity and health among 75 health MSc graduates from a Spanish university. The questionnaire "Religion and Spirituality in Medicine, Perspectives of Physicians" was used. Most students had low levels of religious activities, agreeing that S/R could have a high influence on the health professional-patient relationship (62.6%). Nevertheless, they felt little prepared to address these issues (90.6%) and believed that universities were not providing enough information on this topic (91.9%). The most common barriers for addressing R/S were insufficient time (34.7%) and fear of offending the patients (31.9%). Nurse students tended to believe more on the influence of R/S on patients' health and on the appropriateness of addressing R/S issues. However, religious beliefs were not associated with students' R/S opinions. The incorporation of such topic could potentially promote the spiritual sensitivity of health professionals, improving the holistic care.

Opinions and attitudes on the relationship between spirituality, religiosity and health: A comparison between nursing students from Brazil and Portugal.

AIMS AND OBJECTIVES: To compare the opinions and attitudes of Portuguese-speaking nursing students from Brazil and Portugal on the relationship between religiosity/spirituality and the ability to approach these issues with patients, in their undergraduate training and practice. BACKGROUND: Although there are studies investigating nursing students' opinions concerning religiosity and spirituality in clinical practice, few have investigated if there are cross-cultural differences between countries. DESIGN: Observational, cross-sectional and multicenter study carried out in 2010 and 2011 in Brazil and in 2016 in Portugal. METHODS: A total of 260 third and fourth year nursing students (139 from Portugal and 121 from Brazil) from four nursing schools were included. Religious beliefs (Duke Religion Index), attitudes and opinions about spirituality and health (Curlin's questionnaire) were assessed. A comparison between students from both countries was carried out. RESULTS/FINDINGS: Significant differences were found between nursing students from Brazil and Portugal, which are countries with the same language, but with different nursing training programs and population characteristics. Brazilian students were more religious and have stronger opinions on the influence and appropriateness of spirituality in clinical practice than Portuguese students. However, both groups of students indicated they should be prepared to address religiosity and spirituality with patients, that these subjects should be included in the curriculum and that they were not properly prepared to address spiritual issues. CONCLUSION: Although different opinions and attitudes were found between Brazilian and Portuguese nursing students, more training in these issues should be implemented in the undergraduate education. Cross-cultural studies could help fostering a broad discussion in the field. RELEVANCE TO CLINICAL PRACTICE: These findings could contribute to raise awareness on the importance of improving the training of relational competencies that prepare students to address the dimension of spirituality and religiosity with their patients.

Influence of Religious and Spiritual Elements on Adherence to Pharmacological Treatment.

The objective of this study is to know the influence of religious/spiritual elements on the adherence to pharmacological therapy. The descriptors used for this literature review were "medicine, medication, drug, or treatment," "adherence to treatment," and "religion or spirituality or faith or prayer" in different databases (CINAHL, PsycINFO, PubMed). Finally, 23 articles were selected. Articles available in full text, published between 2010 and 2017, in English or Spanish were included. The results showed that some studies relate positively the R/S and therapeutic adherence, but others determine an opposite or even mixed effect, mainly addressing pathologies such as HIV and other chronic diseases. The influence of religiosity/spirituality on therapeutic adherence requires that health professionals acquire sensitivity and competence to address these issues with their patients.

El factor migratorio como determinante de salud: una intervención transcultural desde la Enfermería del Trabajo / The migratory factor as a determinant of health: A transcultural occupational health nursing intervention

Se presenta un caso clínico de Enfermería del Trabajo en el que la trabajadora manifiesta una sintomatología derivada del estrés generado por el cambio de residencia, además del conjunto de los factores relacionados con este hecho provocados por motivos laborales. Dada la adecuación de la teoría de la diversidad y de la universalidad de los cuidados de Leininger respecto al caso, la valoración de enfermería se realiza siguiendo su modelo del sol naciente (modelo Sunrise). Tras la valoración, se determina que los factores asociados al hecho migratorio son el desencadenante de los síntomas referidos, y se elabora un plan de cuidados con seguimiento por contacto telefónico mensual y nueva evaluación a los 3meses. El abordaje desde una perspectiva holística contenedora de elementos sociales y culturales junto a la utilización de un lenguaje estandarizado enfermero resultan ser de gran importancia en casos como el presentado (AU)

We present a clinical case in occupational health nursing where the worker was showing symptoms of stress caused by a change of residence and related factors at work. A nursing assessment was made following Leininger's theory of Care Diversity and Universality and Sunrise Model, considered suitable for the case. After the assessment, it was determined that the factors associated with the migratory event triggered the reported symptoms, and a care plan was drawn up with monthly telephone contact follow-up and reassessment at 3months. A holistic approach containing social and cultural elements, together with the use of standardised nurse language are very useful in cases such as the one presented (AU)

Interventions to improve working conditions of nursing staff in acute care hospitals: Scoping review.

AIM: To conduct a scoping review to examine and map the interventions proposed for the improvement of the working conditions of nursing staff in acute care hospitals. BACKGROUND: The Registered Nurse Forecasting (RN4CAST) project and other studies have determined the impact that the nursing staff has on the quality of care. The nursing staff's higher levels of burnout, job dissatisfaction and negative perception of the quality of care provided caused worse health outcomes. METHODS: A scoping review was carried out. By searching in SCOPUS, PubMed, CINAHL, Cochrane, Dialnet and in the grey literature, 705 potentially relevant papers were identified. The final analysis included 21 papers and three grey documents. RESULTS: The studies analysed proposed interventions at the macro-management, meso-management and micro-management levels, although the interventions at the macro- and meso-levels produce better staff outcomes. CONCLUSIONS: The findings of this review can be applied to management at different levels: measures to improve the patient-nurse ratio at the macro-management level, the horizontal hierarchies at the meso-management level, the mind-body techniques at the micro-management level. IMPLICATIONS FOR NURSING MANAGEMENT: Nurse managers and leaders should implement interventions at different organisational levels to improve the working conditions of the nursing staff and other health outcomes.

The migratory factor as a determinant of health: A transcultural occupational health nursing intervention. / El factor migratorio como determinante de salud: una intervención transcultural desde la Enfermería del Trabajo.

We present a clinical case in occupational health nursing where the worker was showing symptoms of stress caused by a change of residence and related factors at work. A nursing assessment was made following Leininger's theory of Care Diversity and Universality and Sunrise Model, considered suitable for the case. After the assessment, it was determined that the factors associated with the migratory event triggered the reported symptoms, and a care plan was drawn up with monthly telephone contact follow-up and reassessment at 3months. A holistic approach containing social and cultural elements, together with the use of standardised nurse language are very useful in cases such as the one presented.

Health Impacts of Religious Practices and Beliefs Associated with The Church of Jesus Christ of Latter-Day Saints.

The aim of the study is to discuss the relationship between lifestyle marked by The Church of Jesus Christ of Latter-day Saints and health. PubMed, CINAHL, PsycINFO, WOS y Scopus were the databases used for this literature review, with these descriptors: "Mormons", "mormons religion", "health". Inclusion criteria were articles with full text available, published between 2005 and 2016, in English or Spanish language. Results show that following the restrictive Mormon doctrine generates beneficial effects for the health. Habits related to toxics and food, as well as social support, from family and Mormon community are an important basis for good health. On the other hand, not following the prescriptions or leaving the group, opposed sexual identities or not fulfilling the roles associated with women are associated with worse mental and physical health.

Adecuación de la dieta por razones de salud: intervención enfermera en pacientes con litiasis renal / Adapting the diet due to health reasons: Nursing intervention in patients with renal lithiasis

La litiasis urinaria, de gran incidencia en la actualidad, como la ocasionada por formaciones de cálculos de ácido úrico, tiene una gran relación con nuestros estilos de vida, entre ellos, los hábitos dietéticos. A través de un caso clínico se pretende revisar las principales actuaciones de enfermería que pueden acontecer ante dicha patología. Para lograrlo, se exponen los datos recogidos en la exploración física y valoración enfermera según el modelo de Virginia Henderson, al mismo tiempo que se desarrolla el plan de cuidados completo. Los resultados arrojan la necesidad de instaurar ante esta patología intervenciones estandarizadas de educación para la salud en relación a la alimentación limitada en purinas de las personas que la padecen. La multitud de complicaciones y otros problemas asociados a la estancia hospitalaria dada la reincidencia de litiasis por desconocimiento suponen un riesgo para la calidad de vida de la persona y el mantenimiento de su independencia

The urolithiasis, with a high incidence nowadays, including formations caused by gallstone of uric acid, has a high correlation to our lifestyles and dietary habits. Through a clinic case, it is intended to review the main nursing actions that may occur with this pathology. To achieve this, the data collected on physical examination and nursing assessment on the model of Virginia Henderson, while the full care plan is developed. The results show the need to establish a standardized healthy education intervention, related to a low-pruine healthy diet for people that suffer this disease. The amount of complications and problems associated with recidivism of hospital accommodation because of the ignorance of gallstone cases increase the risk of reducing the quality of life of the patients

[Adapting the diet due to health reasons: Nursing intervention in patients with renal lithiasis]. / Adecuación de la dieta por razones de salud: intervención enfermera en pacientes con litiasis renal.

The urolithiasis, with a high incidence nowadays, including formations caused by gallstone of uric acid, has a high correlation to our lifestyles and dietary habits. Through a clinic case, it is intended to review the main nursing actions that may occur with this pathology. To achieve this, the data collected on physical examination and nursing assessment on the model of Virginia Henderson, while the full care plan is developed. The results show the need to establish a standardized healthy education intervention, related to a low-pruine healthy diet for people that suffer this disease. The amount of complications and problems associated with recidivism of hospital accommodation because of the ignorance of gallstone cases increase the risk of reducing the quality of life of the patients.

Cumulative live birth rate after two single frozen embryo transfers (eSFET) versus a double frozen embryo transfer (DFET) with cleavage stage embryos: a retrospective cohort study.

PURPOSE: According to the latest ART report for Europe, about 13% of pregnancies after frozen embryo transfer are multiple. Our objective was to analyse the impact on the multiple pregnancy rate of two eSFET (elective single frozen embryo transfers) versus a DFET (double frozen embryo transfer) in women aged under 38 years, who had not achieved pregnancy in their fresh transfer and who had at least two vitrified embryos of A/B quality. METHODS: This study was conducted from January 2010 to June 2013 at a public hospital. The couples were divided into three groups. Group DFET: the first cryotransfer of two embryos (105 women); cSFET group: the only cryotransfer of a single vitrified embryo (60 women); eSFET group, individually vitrified embryos: 20 patients included in a clinical trial of single-embryo fresh and frozen transfer and 21 patients who chose to receive eSFET. RESULTS: The clinical pregnancy rate was 38.1% in the DET group and the cumulative clinical pregnancy rate was 43.3% in the eSFET group. There were no significant differences between the DFET and eSFET groups (30.0 vs 34.1%) in cumulative live birth delivery rate. The rate of multiple pregnancies varied significantly between the DFET and eSFET groups (32.5 vs 0%, p < 0.05). CONCLUSIONS: For good-prognosis women aged under 38 years, taking embryo quality as a criterion for inclusion, an eSFET policy can be applied, achieving acceptable cumulative clinical pregnancy and live birth rates and reducing multiple pregnancy rates.