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1.
BMJ Case Rep ; 17(6)2024 Jun 25.
Article in English | MEDLINE | ID: mdl-38925675

ABSTRACT

Soft tissue deficiency in a tooth extraction site in the aesthetic area is a common and challenging clinical situation. This case report demonstrates the successful treatment of extensive gingival recession and buccal bone dehiscence associated with a hopeless tooth. Initially, a connective tissue graft was used to cover the root and thicken the soft tissue. After 2 months, the tooth was extracted, an implant was immediately placed, and a temporary restoration was installed. After 3 months, the soft tissue exhibited a natural and harmonious architecture. A custom zirconia abutment and crown were then fabricated and placed. At the 4-year follow-up, the peri-implant tissue displayed satisfactory aesthetics, with a well-structured buccal bone plate and healthy peri-implant indicators. This two-stage approach, addressing gingival recession first and proceeding with immediate implant placement after soft tissue healing, proved to be a safe and effective method with stable long-term results.


Subject(s)
Esthetics, Dental , Gingival Recession , Humans , Gingival Recession/surgery , Gingival Recession/etiology , Female , Follow-Up Studies , Crowns , Immediate Dental Implant Loading/methods , Tooth Extraction , Male , Dental Implants, Single-Tooth , Adult , Connective Tissue/transplantation , Treatment Outcome , Middle Aged
2.
Eur J Dent ; 2024 May 14.
Article in English | MEDLINE | ID: mdl-38744324

ABSTRACT

This case report addresses the treatment of excessive gingival display (EGD) in the context of maxillary asymmetry, zenith irregularities, and occlusal plane inclination. Digital planning was pivotal in formulating a precise treatment strategy by incorporating facial photographs, digital models, and cone-beam computed tomography data. Parameters, including occlusal plane inclination, teeth position, and lip-to-gingival margin relationships, were considered to ensure treatment alignment with the patient's facial characteristics. Notably, during the planning phase, it was evident that the conventional approach using the cementoenamel junction as the apical limit for incisions would result in asymmetry. Consequently, the gingival margin position was defined in accordance with facial and lip features. The chosen treatment, flapless crown lengthening, was tailored to the patient's thin phenotype and guided by measurements derived from digital planning. Postsurgery, the patient experienced a swift and painless recovery. A harmonious smile with a stable gingival margin position was achieved at the 1-year follow-up, seamlessly complementing the patient's facial attributes. This case underscores the importance of personalized EGD treatment and the value of digital planning in enhancing diagnostic accuracy and precise treatment planning, ultimately facilitating optimal treatment strategies.

3.
Braz Oral Res ; 38: e002, 2024.
Article in English | MEDLINE | ID: mdl-38198302

ABSTRACT

This study aimed to estimate the prevalence and extent of bleeding on probing and calculus in 12-year-old schoolchildren of Quito, Ecuador, and evaluate the associated factors. We conducted an epidemiological survey with a representative sample of 1,100 12-year-old schoolchildren from public schools in the urban area of Quito, Ecuador. We assessed the periodontal health using the Community Periodontal Index (CPI). The prevalence and extent of the periodontal condition was based on the presence of at least one site with bleeding on probing (BOP), and the presence of dental calculus was also evaluated. We used univariate and multiple multilevel Poisson regression analyses to verify the association between the independent variables and the number of sextants with BOP and calculus. The prevalence of BOP and calculus was 92% and 69.9%, respectively. The adjusted mean of the affected sextants was 4.3 and 2.2 for BOP and calculus, respectively. The mother's schooling and malocclusion were associated with the number of sextants with bleeding. The mother's schooling and dental caries experience were associated with calculus. Gingival bleeding and the presence of dental calculus are highly prevalent in 12-year-old schoolchildren from Quito. Gingival bleeding is associated with maternal education and malocclusion, and dental calculus is associated with maternal education and dental caries.


Subject(s)
Dental Caries , Malocclusion , Humans , Child , Ecuador/epidemiology , Cross-Sectional Studies , Dental Calculus/epidemiology , Dental Caries/epidemiology , Gingival Hemorrhage/epidemiology
4.
J Clin Periodontol ; 51(1): 14-23, 2024 01.
Article in English | MEDLINE | ID: mdl-37846853

ABSTRACT

AIM: This investigation aimed to evaluate the 1-year survival of implants placed after staged lateral alveolar ridge augmentation using equine-derived collagenated xenogeneic bone blocks (CXBBs) or autogenous bone block (ABB). MATERIALS AND METHODS: Fifty patients who underwent lateral augmentation in a previous trial were included. The primary outcome measure was implant survival at the 1-year follow-up, and secondary outcomes included implant success, peri-implant clinical and volumetric parameters, pink aesthetic scores (PES) and patient-reported outcome measures. Data analysis involved Fisher's exact test, the Mann-Whitney U-test and the Wilcoxon signed-rank test. RESULTS: In this study, no late implant failures were observed. The cumulative survival rates were 78.6% for the CXBB group and 90.9% for the ABB group, with no difference between the groups. Similarly, the success rates were 53.6% and 63.6%, respectively, showing no significant difference. Peri-implant clinical and volumetric parameters indicated the presence of healthy peri-implant tissues surrounding implants placed in both CXBB- and ABB-augmented sites. PES were 8.5 and 11.0 for implants placed in CXBB- and ABB-augmented sites, respectively. Furthermore, patient satisfaction rates were high and similar between the groups. CONCLUSIONS: Dental implants placed in both CXBB- and ABB-augmented ridges demonstrated no statistically significant differences in clinical, volumetric and aesthetic outcomes, along with high patient satisfaction rates.


Subject(s)
Alveolar Ridge Augmentation , Dental Implants , Animals , Humans , Alveolar Process/surgery , Alveolar Process/pathology , Atrophy/pathology , Bone Transplantation , Dental Implantation, Endosseous , Esthetics, Dental , Follow-Up Studies , Horses , Treatment Outcome
5.
J Periodontal Res ; 59(2): 237-248, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38135675

ABSTRACT

BACKGROUND AND OBJECTIVE: As elsewhere in the world, the prevalence of periodontitis in stages I-II is high in the Latin American population, this scenario emphasizes the need for identification of urgent needs for allocating adequate resources to provide diagnosis, prevention, and treatment of these diseases. The aim of this Delphi study was to predict the trends in periodontology/periodontics in the Latin American region by the year 2030. METHODS: A steering committee and an advisory group of experts in periodontology/periodontics were selected from 16 countries. An open questionnaire of 60 questions was validated and used following the Delphi methodology. RESULTS: Two hundred and twenty-five experts from Latin America answered the two rounds of the questionnaire. Moderate to strong consensus was reached on 45 questions (75%). The prediction was that the prevalence of gingivitis and periodontitis in stages I and II will be maintained, the importance of the link with systemic diseases will increase, and the impact of prevention and periodontal treatment will also increase, mainly in the private sector. There was a strong consensus that plastic and regenerative surgical procedures will increase, as well as the demand for training in the specialty of periodontology. CONCLUSIONS: The present study has provided relevant and useful information on predictions in periodontology/periodontics in Latin America, with important level of consensus among experts. It has been predicted that periodontitis will still be a highly prevalent disease, and its links with other medical conditions should demand more attention by health authorities to develop adequate prevention and management policies and strategies.


Subject(s)
Periodontal Diseases , Periodontitis , Humans , Periodontics , Periodontal Diseases/epidemiology , Periodontal Diseases/therapy , Latin America/epidemiology , Consensus , Delphi Technique , Periodontitis/epidemiology , Periodontitis/therapy
6.
Braz. oral res. (Online) ; 38: e002, 2024. tab
Article in English | LILACS-Express | LILACS, BBO - Dentistry | ID: biblio-1528149

ABSTRACT

Abstract This study aimed to estimate the prevalence and extent of bleeding on probing and calculus in 12-year-old schoolchildren of Quito, Ecuador, and evaluate the associated factors. We conducted an epidemiological survey with a representative sample of 1,100 12-year-old schoolchildren from public schools in the urban area of Quito, Ecuador. We assessed the periodontal health using the Community Periodontal Index (CPI). The prevalence and extent of the periodontal condition was based on the presence of at least one site with bleeding on probing (BOP), and the presence of dental calculus was also evaluated. We used univariate and multiple multilevel Poisson regression analyses to verify the association between the independent variables and the number of sextants with BOP and calculus. The prevalence of BOP and calculus was 92% and 69.9%, respectively. The adjusted mean of the affected sextants was 4.3 and 2.2 for BOP and calculus, respectively. The mother's schooling and malocclusion were associated with the number of sextants with bleeding. The mother's schooling and dental caries experience were associated with calculus. Gingival bleeding and the presence of dental calculus are highly prevalent in 12-year-old schoolchildren from Quito. Gingival bleeding is associated with maternal education and malocclusion, and dental calculus is associated with maternal education and dental caries.

7.
Braz Oral Res ; 37: e124, 2023.
Article in English | MEDLINE | ID: mdl-38126468

ABSTRACT

The Internet is a growing source of knowledge and can provide information about oral health. This ecological study aimed to characterize the interests in toothpaste among Google users from different countries. Our hypothesis was that there would be an increase in Google users' interest in information about toothpaste. This retrospective longitudinal ecological study analyzed the toothpaste-related interest of Google users from 10 countries between January 2004 and December 2020. The monthly variation in relative search volume (RSV) and the main related queries were determined using Google Trends. Autoregressive integrated moving average (ARIMA) forecasting models were built to establish the predictive RSV values for toothpaste for an additional 12 months. Autocorrelation plots and the generalized additive model (GAM) were used to diagnose trends and seasonality in RSV curves. Additionally, the influence of social isolation related to the outbreak of COVID-19 was analyzed. Although not detected by autocorrelation function (ACF) and partial autocorrelation function (PACF) analyses, the heuristic analysis showed an increase in the interest in toothpaste-related information in all countries, with a stable trend observed in the 12-month forecasts, except for the increases in the United Kingdom and South Africa. Also, GAM analyses demonstrated a non-significant monthly or quarterly seasonal influence on data. In addition, social isolation during the COVID-19 pandemic did not influence the online information-seeking behavior of Google Search users linked to this topic. We confirmed the hypothesis that the interest of Google Search users in information about toothpaste increased in all of the 10 assessed countries.


Subject(s)
COVID-19 , Toothpastes , Humans , Retrospective Studies , Search Engine , Pandemics , Oral Health , COVID-19/epidemiology
8.
Clin Oral Implants Res ; 34(8): 863-871, 2023 Aug.
Article in English | MEDLINE | ID: mdl-37309738

ABSTRACT

AIM: To compare, at different levels from the alveolar crest, the radiographic outcomes of equine-derived collagenated xenogeneic bone blocks (CXBB) and autogenous bone blocks (ABB) used for lateral alveolar ridge augmentation. MATERIALS AND METHODS: Sixty-four patients with tooth gaps in atrophic alveolar ridges with ≤4 mm were randomly assigned to lateral augmentation using CXBB or ABB. The lateral bone thickness (LBT) was measured 2, 4, 6, 8, and 10 mm below the alveolar crest using CBCT scans obtained before augmentation surgery and at 30 weeks, prior to implant placement. Statistical analysis was performed using Shapiro-Wilk, Fisher's exact, Mann-Whitney, and Wilcoxon signed-rank tests. RESULTS: Both CXBB and ABB resulted in significant total and buccal LBT gains at 2, 4, 6, 8, and 10 mm. LBT gains were similar between CXBB- and ABB-augmented sites, except for greater buccal LBT gains at 8 mm at CXBB-augmented sites. While ABB-augmented sites gained vertical bone height, CXBB-treated sites suffered vertical bone loss (CXBB: -0.16 mm; ABB: 0.38 mm, p < .0009). CONCLUSIONS: CXBB and ABB were both associated with significant and similar LBT gains at 30 weeks.


Subject(s)
Alveolar Ridge Augmentation , Dental Implantation, Endosseous , Animals , Horses , Dental Implantation, Endosseous/methods , Bone Transplantation/methods , Alveolar Process/diagnostic imaging , Alveolar Process/surgery , Alveolar Ridge Augmentation/methods , Guided Tissue Regeneration, Periodontal/methods
9.
Braz Oral Res ; 37: e038, 2023.
Article in English | MEDLINE | ID: mdl-37132726

ABSTRACT

Accumulated evidence has shown that the oral cavity may be an important reservoir for SARS-CoV-2. Some authors have suggested that the use of mouthrinses could reduce SARS-CoV-2 viral load in the saliva. Thus, the aim of this review was to synthesize evidence about the efficacy of mouthrinses in reducing the salivary viral load of SARS-CoV-2. 2. Nine randomized controlled trials (RCTs) have investigated the efficacy of different mouthrinses in reducing salivary SARS-CoV-2 loads. Various active ingredients have been tested in these trials: 0.5%,1% and 2% povidone-iodine, 0.2% and 0.12% chlorhexidine (CHX), 0.075% cetylpyridinium chloride (CPC), 0.075% CPC with Zinc lactate, 1% and 1.5% hydrogen peroxide (HP), 1.5% HP + 0.12% CHX and ß-cyclodextrin and citrox. The studies reported an intra-group reduction in the salivary levels of the virus, when compared with the baseline. However, the majority of these trials failed to demonstrate a significant inter-group difference between active groups and the control group relative to the decrease in salivary SARS-CoV-2 loads. Although promising, these results should be confirmed by larger trials.


Subject(s)
Anti-Infective Agents, Local , COVID-19 , Humans , SARS-CoV-2 , Mouthwashes/therapeutic use , COVID-19/prevention & control , Chlorhexidine , Mouth , Hydrogen Peroxide , Cetylpyridinium/therapeutic use , Anti-Infective Agents, Local/therapeutic use
10.
Quintessence Int ; 54(7): 536-547, 2023 Jul 17.
Article in English | MEDLINE | ID: mdl-37013667

ABSTRACT

OBJECTIVE: This pilot, prospective interventional study aimed to analyze the influence of supracrestal tissue height when using the one abutment-one time concept at the time of implant placement, on peri-implant hard and soft tissue remodeling in esthetic areas. The definitive crown was placed 7 days later. METHOD AND MATERIALS: Facial mucosal margin position, mesial and distal papilla levels, and mesial and distal marginal bone loss were assessed after 7 days (placement of the definitive crown), and 1, 2, 3, 6, and 12 months after implant placement. Patients were classified according to the supracrestal tissue height as thin (< 3 mm) and thick (≥ 3 mm). RESULTS: Fifteen patients fulfilled the eligibility criteria and were included in the study. Eight presented a thick supracrestal tissue height and seven a thin supracrestal tissue height. After 12 months, the implant success rate was 100%. The mean recession at the facial mucosal margin position was -0.47 ± 0.57 mm and -0.19 ± 0.41 mm in thin and thick groups, respectively (P = .29). The mean mesial papilla level recession was -0.19 ± 0.06 mm in the thin group and -0.01 ± 0.07 mm in the thick group (P < .01), and the mean distal papilla level recession was -0.15 ± 0.09 mm in the thin group and 0.00 ± 0.15 mm in the thick group (P < .05). The mean bone loss was -0.21 ± 0.18 mm and -0.04 ± 0.14 mm in the thin and thick groups, respectively (P < .05). CONCLUSION: Single maxillary anterior implants with thin supracrestal tissue height (< 3 mm) at the time of implant placement had greater bone loss and papillary recession than implants with a thick soft tissue height (≥ 3 mm), even when using the one abutment-one time concept.


Subject(s)
Dental Implants, Single-Tooth , Dental Implants , Humans , Prospective Studies , Esthetics, Dental , Dental Implantation, Endosseous/methods , Maxilla/surgery , Treatment Outcome
11.
Clin Oral Implants Res ; 34(6): 543-554, 2023 Jun.
Article in English | MEDLINE | ID: mdl-36939434

ABSTRACT

OBJECTIVE: The aim of this study was to systematically analyze the influence of smoking on the incidence of peri-implantitis. MATERIALS AND METHODS: The search was performed in the National Library of Medicine (MEDLINE-PubMed), SCOPUS, EMBASE, and ISI Web of Science databases (finished on November 30, 2022). Systematic review and meta-analysis were conducted according to PRISMA statement. Prospective cohort studies that evaluate the incidence of peri-implantitis in smokers and non-smokers were included. Two authors independently searched for eligible studies, screened titles, and abstracts, did the full-text analysis, extracted data, and performed the risk-of-bias assessment. The results were summarized through random-effects meta-analyses. The GRADE method was used to determine the certainty of evidence. RESULTS: A total of 7 studies with 702 patients and 1959 implants were included for analysis. The meta-analysis revealed a significant difference between smokers and non-smokers for the risk of peri-implantitis in the implant-based (p < .0001) and patient-based analysis (p = .003). A strong association between smoking and the risk for peri-implantitis was verified at the implant level (RR: 2.04, 95% CI: 1.46-1.85) and the patient level (RR: 2.79, 95% CI: 1.42-5.50). CONCLUSIONS: Moderate certainty evidence suggests that smoking is associated with peri-implantitis compared to non-smoking at the patient and implant levels.


Subject(s)
Dental Implants , Peri-Implantitis , Humans , Peri-Implantitis/epidemiology , Peri-Implantitis/etiology , Dental Implants/adverse effects , Incidence , Prospective Studies , Databases, Factual
12.
Braz Oral Res ; 37: e001, 2023.
Article in English | MEDLINE | ID: mdl-36629587

ABSTRACT

The purpose of this study was to compare the outcomes of a modified gingival graft technique, in which the released flap is positioned and sutured over the graft, with the conventional free gingival graft (FGG) procedure, when both are used for gingival augmentation. A 12-month, multicenter parallel randomized controlled trial was conducted. Subjects with buccal RT2 gingival recessions and keratinized tissue width (KTW) < 2 mm in at least one mandibular incisor were randomized to control group (n = 20; conventional FGG) or test group (n = 20; modified FGG; flap sutured over FGG using sling sutures). The primary outcome (KTW) was measured at baseline and after 3, 6 and 12 months, as was keratinized tissue thickness (KTT). Postoperative pain (POP) and analgesic intake were also recorded. Both techniques promoted a significant increase in KTW and KTT when compared to baseline (p < 0.05) with no significant differences between groups (KTW change of 6.1±1.5 mm and 5.4±1.6 mm, for control and test, respectively; p=0.16). However, test group patients reported less POP after 7 days and used less analgesic medication than control group patients (p < 0.05). We concluded that the modified FGG was comparable to conventional FGG in augmenting keratinized tissue width and thickness at mandibular incisors, but resulted in less patient morbidity.


Subject(s)
Gingiva , Gingival Recession , Humans , Treatment Outcome , Gingiva/transplantation , Gingival Recession/surgery , Surgical Flaps/surgery , Dental Care
13.
Article in English | MEDLINE | ID: mdl-36661880

ABSTRACT

This prospective longitudinal study evaluated the peri-implant soft tissue remodeling, marginal bone levels, and implant success rate of immediately placed single implants-which received a definitive zirconia abutment and provisional restoration at implant placement-in the maxillary esthetic zone. The final crown was delivered 7 days later. Patients (n = 26) presenting a single extraction-indicated lateral or central incisor with adequate bone volume were eligible for this study. Mesial and distal papilla levels (MPL and DPL, respectively), facial gingival level (FGL), and mesial and distal marginal bone levels (MMBL and DMBL, respectively) were assessed after 7 days and at 1, 2, 3, 6, and 12 months. Patients were classified according to gingival phenotype: thin (≤ 2 mm) or thick (> 2 mm). After 1 year, the implant success rate was 100%. Mean soft tissue recession was -0.04 ± 0.15 mm (MPL), -0.09 ± 0.02 mm (DPL), and -0.13 ± 0.18 mm (FGL). Mean bone remodeling at 1 year was 0.12 ± 0.17 mm (MMBL) and 0.13 ± 0.18 mm (DMBL). The marginal interproximal bone was above the implant platform in 100% of sites. Patients with thick phenotype showed significantly less papillary recession than thin-phenotype patients. Minimal peri-implant hard and soft tissue changes were observed at the 1-year follow-up.


Subject(s)
Dental Implants, Single-Tooth , Dental Implants , Immediate Dental Implant Loading , Treatment Outcome , Longitudinal Studies , Esthetics, Dental , Maxilla/surgery
14.
Braz. oral res. (Online) ; 37: e001, 2023. tab, graf
Article in English | LILACS-Express | LILACS, BBO - Dentistry | ID: biblio-1420955

ABSTRACT

Abstract The purpose of this study was to compare the outcomes of a modified gingival graft technique, in which the released flap is positioned and sutured over the graft, with the conventional free gingival graft (FGG) procedure, when both are used for gingival augmentation. A 12-month, multicenter parallel randomized controlled trial was conducted. Subjects with buccal RT2 gingival recessions and keratinized tissue width (KTW) < 2 mm in at least one mandibular incisor were randomized to control group (n = 20; conventional FGG) or test group (n = 20; modified FGG; flap sutured over FGG using sling sutures). The primary outcome (KTW) was measured at baseline and after 3, 6 and 12 months, as was keratinized tissue thickness (KTT). Postoperative pain (POP) and analgesic intake were also recorded. Both techniques promoted a significant increase in KTW and KTT when compared to baseline (p < 0.05) with no significant differences between groups (KTW change of 6.1±1.5 mm and 5.4±1.6 mm, for control and test, respectively; p=0.16). However, test group patients reported less POP after 7 days and used less analgesic medication than control group patients (p < 0.05). We concluded that the modified FGG was comparable to conventional FGG in augmenting keratinized tissue width and thickness at mandibular incisors, but resulted in less patient morbidity.

15.
Braz. oral res. (Online) ; 37: e038, 2023. tab
Article in English | LILACS-Express | LILACS, BBO - Dentistry | ID: biblio-1430041

ABSTRACT

Abstract Accumulated evidence has shown that the oral cavity may be an important reservoir for SARS-CoV-2. Some authors have suggested that the use of mouthrinses could reduce SARS-CoV-2 viral load in the saliva. Thus, the aim of this review was to synthesize evidence about the efficacy of mouthrinses in reducing the salivary viral load of SARS-CoV-2. 2. Nine randomized controlled trials (RCTs) have investigated the efficacy of different mouthrinses in reducing salivary SARS-CoV-2 loads. Various active ingredients have been tested in these trials: 0.5%,1% and 2% povidone-iodine, 0.2% and 0.12% chlorhexidine (CHX), 0.075% cetylpyridinium chloride (CPC), 0.075% CPC with Zinc lactate, 1% and 1.5% hydrogen peroxide (HP), 1.5% HP + 0.12% CHX and ß-cyclodextrin and citrox. The studies reported an intra-group reduction in the salivary levels of the virus, when compared with the baseline. However, the majority of these trials failed to demonstrate a significant inter-group difference between active groups and the control group relative to the decrease in salivary SARS-CoV-2 loads. Although promising, these results should be confirmed by larger trials.

16.
Braz. oral res. (Online) ; 37: e124, 2023. tab, graf
Article in English | LILACS-Express | LILACS, BBO - Dentistry | ID: biblio-1528129

ABSTRACT

Abstract The Internet is a growing source of knowledge and can provide information about oral health. This ecological study aimed to characterize the interests in toothpaste among Google users from different countries. Our hypothesis was that there would be an increase in Google users' interest in information about toothpaste. This retrospective longitudinal ecological study analyzed the toothpaste-related interest of Google users from 10 countries between January 2004 and December 2020. The monthly variation in relative search volume (RSV) and the main related queries were determined using Google Trends. Autoregressive integrated moving average (ARIMA) forecasting models were built to establish the predictive RSV values for toothpaste for an additional 12 months. Autocorrelation plots and the generalized additive model (GAM) were used to diagnose trends and seasonality in RSV curves. Additionally, the influence of social isolation related to the outbreak of COVID-19 was analyzed. Although not detected by autocorrelation function (ACF) and partial autocorrelation function (PACF) analyses, the heuristic analysis showed an increase in the interest in toothpaste-related information in all countries, with a stable trend observed in the 12-month forecasts, except for the increases in the United Kingdom and South Africa. Also, GAM analyses demonstrated a non-significant monthly or quarterly seasonal influence on data. In addition, social isolation during the COVID-19 pandemic did not influence the online information-seeking behavior of Google Search users linked to this topic. We confirmed the hypothesis that the interest of Google Search users in information about toothpaste increased in all of the 10 assessed countries.

17.
J Clin Periodontol ; 49(11): 1158-1168, 2022 11.
Article in English | MEDLINE | ID: mdl-35833539

ABSTRACT

AIM: To compare the efficacy of equine-derived collagenated xenogeneic bone blocks (CXBB) and autogenous bone block (ABB) for lateral alveolar ridge augmentation and two-stage implant placement. MATERIALS AND METHODS: Sixty-four patients with tooth gaps up to four teeth and atrophic alveolar ridges with ≤4 mm were randomly assigned to lateral augmentation using CXBB or ABB. Lateral bone thickness (LBT) was measured 2 mm below the alveolar crest at augmentation surgery and 30 weeks later at implant placement. Implant-related outcomes, adverse events, surgery duration, pain sensation, analgesic consumption, and oral health-related quality of life were also assessed. Data were analysed using Fisher's exact, Mann-Whitney, and Wilcoxon signed-rank tests. RESULTS: At 30 weeks, the median change in LBT amounted to 2.90 (CXBB) and 3.00 (ABB), respectively. Secondary endpoints demonstrated similar results for CXBB and ABB in terms of possibility to place an implant, need to perform a secondary bone augmentation at implant placement and rate of complications. Early implant failure was 20% for CXBB and 10% for ABB, with no difference between the groups. Pain scores and post-operative consumption of analgesics were significantly lower in the CXBB group than in the ABB group, especially during the first days post-surgery. CONCLUSIONS: CXBB is non-inferior to ABB for horizontal alveolar ridge augmentation and two-stage implant placement.


Subject(s)
Alveolar Ridge Augmentation , Dental Implantation, Endosseous , Alveolar Process/surgery , Alveolar Ridge Augmentation/methods , Animals , Bone Transplantation/methods , Dental Implantation, Endosseous/methods , Horses , Pain/etiology , Quality of Life
18.
J Clin Periodontol ; 49(11): 1121-1132, 2022 11.
Article in English | MEDLINE | ID: mdl-35851689

ABSTRACT

AIM: To evaluate the frequency of side effects associated with intake of metronidazole (MTZ) + amoxicillin (AMX) in periodontal treatment, and to explore associations between these events and patients' features. MATERIALS AND METHODS: Data of five randomized clinical trials testing MTZ + AMX adjunctive to mechanical therapy were evaluated. Volunteers answered an adverse event questionnaire. RESULTS: Information from 656 subjects was assessed. The frequency of side effects in the antibiotic- and placebo-treated groups ranged from 1.0% to 17.7% and 0.9% to 13.7%, respectively. The events more frequently observed in the antibiotic than in the placebo group were diarrhoea and metallic taste (p < .05). Diabetes significantly raised the odds of a patient reporting discomfort (odds ratio [OR] = 2.6), diarrhoea (OR = 4.0), weakness (OR = 6.0) and excessive sleepiness (OR = 2.9). In systemically healthy volunteers, using antibiotics 3 months post-mechanical treatment (healing phase) (OR = 3.0), being a woman (OR = 3.9) and aged ≤49 (OR = 4.5) significantly increased the chances of reporting adverse events. CONCLUSIONS: The occurrence of side effects during MTZ + AMX treatment ranged from uncommon (1%) to very common (17.7%). The main factors raising the chances of a patient reporting adverse events were diabetes and taking antibiotics in the healing phase, instead of in the active phase of treatment. Patients ≤ 49 years old and females also tend to report more side effects.


Subject(s)
Amoxicillin , Chronic Periodontitis , Amoxicillin/adverse effects , Anti-Bacterial Agents/adverse effects , Chronic Periodontitis/therapy , Dental Scaling , Diarrhea/chemically induced , Diarrhea/drug therapy , Double-Blind Method , Female , Humans , Metronidazole/adverse effects , Middle Aged , Randomized Controlled Trials as Topic , Retrospective Studies
19.
Article in English | MEDLINE | ID: mdl-35060975

ABSTRACT

This study aimed to simultaneously assess hard and soft tissues alterations and their proportions after alveolar ridge preservation (ARP). Participants (n = 65) who were previously enrolled in a clinical trial investigating ARP healing were selected. The CBCT DICOM (Digital Imaging and Communications in Medicine) and the cast STL (stereolithographic) files of each subject were imported, segmented, and superimposed. A cross-section view of the superimposed image presented the outlines from each DICOM and STL file. The center of preserved ridge was selected in the superimposed image and used to draw the reference lines to realize the measurements. Horizontal linear measurements determined ridge width (RW) and its respective hard/soft tissue proportion (H:S) at 1, 3, 5, and 7 mm below the buccal bone crest immediately after ARP and at the 4-month follow-up. At 1 mm, the baseline RW was 11.6 mm and reduced to 10 mm after 4 months. The baseline H:S was 65%:35% and was 43%:57% at the 4-month follow-up. Considering only the buccal half of the ridge, baseline H:S was 77%:23%, while after 4 months it shifted to 58%:42%. A similar pattern was observed at 3, 5, and 7 mm but with decreased resorption degree. The present study showed that hard tissue is mostly responsible for RW loss after healing, especially in the first 3 mm below the buccal bone crest. Soft tissue partially compensated for the hard tissue shrinkage, gaining thickness in the analyzed areas.


Subject(s)
Alveolar Bone Loss , Alveolar Ridge Augmentation , Bone Substitutes , Alveolar Bone Loss/diagnostic imaging , Alveolar Bone Loss/prevention & control , Alveolar Process/diagnostic imaging , Alveolar Process/surgery , Bone Substitutes/therapeutic use , Humans , Tooth Extraction , Tooth Socket/diagnostic imaging , Tooth Socket/surgery
20.
J Clin Periodontol ; 49(1): 39-47, 2022 01.
Article in English | MEDLINE | ID: mdl-34708422

ABSTRACT

AIM: To compare tissue changes at implant sites previously treated with two biomaterials for alveolar ridge preservation (ARP) in the aesthetic zone, 1 year after restoration. MATERIALS AND METHODS: Sixty-six participants were treated with ARP using demineralized bovine bone mineral (DBBM) or DBBM +10% of collagen (DBBM-C), both covered with a collagen matrix (CM). Dental implants were placed, and definitive crowns were installed. Silicon impressions were taken before tooth extraction (T0), 2 weeks after crown insertion (T1) and 1 year after restoration (T2). Mid-facial mucosal level change (MLC), soft tissue thickness changes (TT), and marginal bone loss (MBL) were analysed using inter-group comparisons. RESULTS: Fifty-four participants were included in the analysis. The mid-facial level change between T0-T1 and T1-T2 showed no statistical difference between DBBM and DBBM-C. Between T0 and T1 for soft tissue thickness, DBBM performed significantly better at 3 and 5 mm below the mucosal margin. From T1 to T2, no significant differences between groups were found at any level for soft tissue thickness and MBL. CONCLUSION: At the aesthetic zone, advanced recession from tooth extraction to crown placement can be expected at sites treated with ARP regardless of biomaterial used. However, after crown insertion, tissue stability can be predicted.


Subject(s)
Alveolar Bone Loss , Alveolar Ridge Augmentation , Alveolar Bone Loss/prevention & control , Alveolar Process/surgery , Animals , Cattle , Esthetics, Dental , Follow-Up Studies , Humans , Tooth Extraction , Tooth Socket/surgery
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