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1.
Eur J Orthop Surg Traumatol ; 28(8): 1537-1542, 2018 Dec.
Article in English | MEDLINE | ID: mdl-30003340

ABSTRACT

Internal fixation with volar locking plates has revolutionized the treatment of distal radius fractures. Manufacturers have introduced plate designs that closely follow the anatomy of the distal radius. However, use of volar plates has also led to the emergence of new types of complications. While the use of monoaxial or polyaxial locking screws and of minimally invasive techniques (arthroscopy, preservation of pronator quadratus) increases the cost of the surgical procedure, it results in a tangible benefit for patients, allowing them to move their wrist almost immediately after surgery and to quickly regain their autonomy. We reviewed the literature to analyze the level of proof.


Subject(s)
Bone Plates , Fracture Fixation, Internal/instrumentation , Radius Fractures/surgery , Fracture Fixation, Internal/adverse effects , Humans , Postoperative Complications/etiology , Prosthesis Design
2.
Placenta ; 59: 116-123, 2017 Nov.
Article in English | MEDLINE | ID: mdl-28673520

ABSTRACT

Previous clinical studies have shown the efficacy of a two-stage surgical procedure - the induced membrane (IM) technique - for reconstruction of large bone defects or bone non-union. The first stage involves radical debridement and insertion of a cement spacer into the bone defect. The second stage, performed weeks to months later, consists of removing the spacer while leaving the foreign body membrane induced by the cement in place, and then filling the cavity with bone autograft. The IM has been shown to (1) act as a protective physical barrier by preventing bone autograft resorption and (2) act as a bioreactor by promoting healing through revascularisation and growth factor secretion, and by concentrating mesenchymal stem cells (MSC) with osteogenic properties. New solutions to reduce this surgical procedure to a single step are being explored, for example by using an IM-like bioactive and protective barrier inserted into the bone defect at the same time as bone graft.


Subject(s)
Amnion/physiology , Amnion/transplantation , Bone Regeneration , Bone Transplantation , Foreign-Body Reaction , Amnion/anatomy & histology , Animals , Cementoplasty , Humans
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