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Bioorg Med Chem Lett
; 12(12): 1567-70, 2002 Jun 17.
Article
in English
| MEDLINE
| ID: mdl-12039563
ABSTRACT
Inspired by the structure of tannic acid, first- to third-generation dendrimers containing two, four, and eight galloyl moieties were synthesized. Stability, antioxidant activity and collagen cross-linking activity of the natural product and its dendrimer analogues were compared. The experimental results indicate that polygalloyl dendrimers might be used as new lead compounds to improve the long-term healing characteristics of burn wounds.