Effects of different nutrition interventions on sarcopenia criteria in older people: A study protocol for a systematic review of systematic reviews with meta-analysis.

BACKGROUND: Sarcopenia, a subject of extensive research, has led to numerous clinical trials and systematic reviews (SR). These reviews aid healthcare professionals by summarizing results and conducting meta-analyses, enhancing reliability. However, the abundance of reviews complicates decision-making on sarcopenia management. To address this, SR of SR have emerged, consolidating data from various sources into comprehensive documents. OBJECTIVE: To assess the isolated impact of dietary interventions on sarcopenia's diagnostic criteria for older individuals. METHODS: A study protocol for a SR of SR, following Cochrane and PRISMA recommendations. The search strategy includes the MeSH 'sarcopenia' and its subheadings; 'aged' and its subheadings; 'nutrition' and its subheadings; and filter 'systematic review', performed at main databases. Selected studies must include older adults, submitted to nutritional interventions compared to control groups. Quantitative analyses will use inverse variance statistic method (random effects); the effect measures mean difference. Heterogeneity measured with Q-Test. RESULTS: The results of this SR of SR may provide valuable information about the sarcopenia treatment, deepening the knowledge about. CONCLUSION: This protocol is reproducible, requires low cost and personnel, and may allow a higher understanding on sarcopenia treatment and management on older people.

Influencia de los revestimientos dentales en la adaptación marginal e interna de las cofias metálicas. Estudio in vitro / Influence of dental investments on the marginal and internal adaptation of metal copings. In vitro study

Objetivo. Evaluar la influencia de diferentes marcas de revestimientos dentales en la adaptación marginal e interna de las cofias metálicas. Método. La investigación fue in vitro, analítico, experimental y transversal; para ello, se confeccionaron 48 cofias metálicas, las cuales fueron cementadas en dientes humanos previamente tallados, luego las cofias fueron cortadas mesio-distalmente para evaluar su adaptación. La adaptación fue evaluada usando un estereomicroscopio Leica DM6000M. Para determinar si hay diferencia en la adaptación marginal e interna se empleó el análisis de varianza, la prueba de comparación múltiple y la prueba de Duncan. Adicionalmente, la prueba de Fisher, se utilizó para evaluar la adaptación total. Resultados. La mejor adaptación marginal e interna de las cofias metálicas lo presenta el revestimiento Fórmula 1 (Whipmix), seguido del Castorit súper C (Dentaurum) y Bellasun (Bego). Conclusión. Los revestimientos dentales no mostraron influencia en la adaptación marginal; sin embargo, si mostraron influencia en la adaptación interna.

Objective. To evaluate the influence of different brands of dental investments on the marginal and internal adaptation of metal copings. Method. The research was in vitro, analytical, experimental and transversal. For this, 48 metal copings were made, which were cemented on previously carved human teeth, then the copings were cut mesio-distally to evaluate their adaptation. The adaptation was evaluated using a Leica DM6000M stereomicroscope. To determine if there is a difference between marginal and internal adaptation; the analysis of variance, the multiple comparison test and the Duncan test were used. Furthermore, Fisher's exact test was used to evaluate the total adaptation. Results. The best marginal and internal adaptation of metal copings is presented by the Formula 1 coating (Whipmix), followed by Castorit super C (Dentaurum) and Bellasun (Bego). Conclusion. Dental investments did not show influence on marginal adaptation; however, they did show influence on internal adaptation.

Análisis In vitro de yesos dentales de alta resistencia y baja expansión disponibles en Perú / In vitro analysis of high resistance and low expansion dental plasters available in Peru

Objetivo. Comparar la dureza, estabilidad dimensional y resistencia a la compresión de los yesos dentales de alta resistencia y baja expansión disponibles en el Perú. Métodos. Se realizó un estudio descriptivo, observacional y transversal. Se confeccionaron muestras de forma cilíndrica (8) y rectangular (8), de siete yesos dentales de alta resistencia y baja expansión. Se evaluó la dureza utilizando el Durómetro Universal Identec, la estabilidad dimensional con un calibrador digital y la resistencia a compresión con la Máquina de Ensayo Universal. Para determinar si hay diferencia en cada una de estas propiedades se empleó el análisis de varianza, la prueba F y la prueba de Duncan. Además, se empleó la prueba de comparación de medias, t de Student, para evaluar si difieren con los valores de la ADA (Asociación Dental Americana). Resultados. La dureza, estabilidad dimen-sional y resistencia a la compresión promedio de los yesos dentales presentó diferencias significativas (p<0.05) entre cada uno con los promedios estándares establecidos por la ADA. Conclusiones. En relación resistencia a la compresión el 100% de los yesos analizados cumplen con los parámetros establecidos por la ADA, en relación estabilidad dimensional solo el 28.6% y el 100% no alcanzan los estándares de dureza promedio establecidos por la ADA.

Objective. To compare the hardness, dimensional stability, and compressive strength of high-strength, low-expansion dental plasters available in Peru, according to ADA criteria. Methods. A descriptive, observational and cross-sectional study was developed. A selection of 8 cylindrical-shaped samples and 8 rectangular- shaped ones, from seven high-resistance, low-expansion dental plasters were fabricated. The hardness was evaluated using the Identec Universal Durometer. Dimensional stability was evaluated with a digital caliper and compressive strength was evaluated with the Instron Universal Testing Machine. To determine if there is a difference in each of these properties, the analysis of variance, F test, and the Duncan's test were used. In addition, to assess whether these values differ from those of the ADA, the mean comparison test, student's t table, were used. Results. The hardness, dimensional stability and average compressive strength of the high-strength, low-expansion dental plasters showed that there are significant di-fferences (p<0.05) between each of the dental plasters and with the standard averages established by the American Dental Association. (ADA). Conclusions. 100% of the high-strength, low-expansion dental casts meet the parameters established by the ADA in terms of their compressive strength, only 28.6% of these comply with the ADA in terms of dimensional stability and that 100% of these do not meet the average hardness standards established by the ADA.

Atuação do fisioterapeuta no serviço de emergência de um hospital de pronto socorro referência em trauma / The role of physical therapists in the emergency room of a trauma hospital

Emergências hospitalares são portas de entrada para pacientes graves com potencial risco de morte. Em um hospital referência em trauma, a função do fisioterapeuta dentro da equipe multiprofissional ainda tem necessidade de ser bem estabelecida. Objetivo: Discorrer sobre a atuação do fisioterapeuta no serviço de emergência de um hospital de pronto socorro referência em trauma e apresentar o perfil do paciente atendido. Método: Trata-se de uma pesquisa observacional descritiva, de caráter transversal retrospectiva a partir da análise dos atendimentos fisioterapêuticos registrados em prontuários de pacientes hospitalizados. Resultados: As causas mais frequentes de internação dos pacientes atendidos pela equipe de fisioterapia foram quedas (51,7%), acidentes de trânsito (14,9%), cardiovasculares (9,2%), agressões (9,1%), outros (8,3%) e respiratórias (6,8%). Quedas da própria altura com fratura de fêmur associadas representaram 26,4% da amostra. Nestes pacientes as condutas mais utilizadas pelos fisioterapeutas foram orientações, exercícios respiratórios, exercícios no leito e ajustes de posicionamento. O fisioterapeuta teve atuação com pacientes com pneumotórax, hemotórax ou hemopneumotórax submetidos à drenagem torácica, por meio de exercícios respiratórios expansivos, saída do leito e deambulação precoce. Observou-se também atuação com os pacientes em ventilação mecânica invasiva e não invasiva na sala vermelha. Conclusão: O fisioterapeuta, fazendo parte da equipe multiprofissional, apresenta importante atuação nas salas de emergência de um hospital de trauma, tal como o atendimento a pacientes submetidos a ventilação mecânica invasiva e não invasiva, uso de técnicas de fisioterapia respiratória para expansão pulmonar e remoção de secreções bem como a utilização de técnicas de cinesioterapia para manutenção e ganho de força muscular e funcionalidade.

Hospital emergencies are gateways to critically ill patients with potential risk of death. In a trauma referral hospital, the physical therapists role within the multiprofessional team must still be well established. Objective: To discuss the role of the physical therapist in the emergency department of a reference trauma hospital and to present the profile of the patients admitted to hospitalization. Method: This is a descriptive, observational, cross-sectional study that analyzes physiotherapy and records of hospitalized patients. Results: The most frequent causes of hospitalization of patients treated by the physiotherapy team were falls (51.7%), traffic accidents (14.9%), cardiovascular diseases (9.2%), assaults (9.1%), and respiratory (6.8%). Falls from standing height with associated femur fractures represented 26.4% of the records. With these patients, the procedures most used by physical therapists were orientations, breathing exercises, bedside exercises, and positioning adjustments. With lung-expanding breathing exercises, bedside exercises, and early walking, the physical therapist treated patients with pneumothorax, hemothorax, or hemopneumothorax who underwent thoracic drainage. Physical therapists also treated patients under invasive and non-invasive mechanical ventilation in the red ward. Conclusion: The physical therapist, as part of the multiprofessional team, has an essential role in the emergency rooms of a trauma hospital, such as care for patients undergoing invasive and non-invasive mechanical ventilation, use of respiratory physiotherapy techniques for lung expansion and removal of secretions, as well as the use of kinesiotherapy techniques to maintain and gain muscle strength and functionality.

Evaluating pollution-related damage and restoration success in urban forests with participatory monitoring and digital tools.

Peri-urban forest monitoring requires indicators of vegetation damage. An example is the sacred fir (Abies religiosa) forests surrounding Mexico City, which have been heavily exposed to tropospheric ozone, a harmful pollutant, for over 4 decades. We developed a participatory monitoring system with which local community members and scientists generated data on ozone tree damage. Santa Rosa Xochiac rangers (13) used the digital tool KoboToolBox to record ozone damage to trees, tree height, tree ages, tree condition, tree position, and whether the tree had been planted. Thirty-five percent of the trees (n = 1765) had ozone damage. Younger trees had a lower percentage of foliage damaged by ozone than older trees (p < 0.0001), and asymptomatic trees tended to be younger (p < 0.0001). Symptomatic trees were taller than asymptomatic trees of the same age (R2 c  = 0.43, R2 m  = 0.27). Involving local communities facilitated forest monitoring and using digital technology improved data quality. This participatory system can be used to monitor forest condition change over time and thus aids restoration efforts driven by government or local communities' interests, facilitating local decision-making.

Evaluación del daño relacionado a la contaminación y del éxito de la restauración de los bosques urbanos con un monitoreo participativo y herramientas digitales Resumen El monitoreo de los bosques periurbanos requiere indicadores de daños en la vegetación. Un ejemplo son los bosques de abeto (Abies religiosa) que rodean la Ciudad de México, pues desde hace más de 4 décadas han estado expuestos al ozono troposférico, un contaminante nocivo. Desarrollamos un sistema de monitoreo participativo con el que miembros de la comunidad local y científicos generaron datos sobre los daños causados por el ozono en los árboles. Los guardabosques de Santa Rosa Xochiac (133) utilizaron la herramienta digital KoboToolBox para registrar los daños causados por el ozono en los árboles, su altura, edad, estado, posición y si eran árboles plantados. El 35% de los árboles (n = 1,765) presentó daños por ozono. Los árboles más jóvenes tenían un menor porcentaje de follaje dañado por el ozono que los árboles más viejos (p<0.0001), y los árboles asintomáticos tendían a ser más jóvenes (p<0.0001). Los árboles sintomáticos eran más altos que los asintomáticos de la misma edad (R2 c = 0.43, R2 m = 0.27). La participación de las comunidades locales facilitó el monitoreo forestal y el uso de tecnología digital mejoró la calidad de los datos. Este sistema participativo puede utilizarse para monitorear los cambios en el estado de los bosques a lo largo del tiempo y contribuir a los esfuerzos de restauración impulsados por el gobierno o las comunidades locales, facilitando la toma de decisiones a nivel local.

Urinary incontinence and quality of life in high-performance swimmers: An observational study.

Each day more women around the world practice high impact physical activities and this may be a risk factor for urinary incontinence (UI) in young. We verified the prevalence of UI and the impact in quality of life (QoL) in high-performance swimmers, through a cross-sectional observational study with 9 high performance swimmers and 9 sedentary women who responded the International Consultation on incontinence Questionnaire - Short Form (ICIQ-SF), participated in a functional evaluation of pelvic floor muscles with bidigital palpation and pad test. We verifed that was present in 78% of high-performance swimmers, and the quality of life was significantly worse (p =.037) when compared to sedentary women. These findings led us to conclude that presence of UI affects the quality of life, even if it is not a factor of abandonment of the sport.

Termoterapia associada com treinamento de flexibilidade não aprimora a amplitude de movimento de joelhos em adultos saudáveis: revisão sistemática de ensaios clínicos randomizados com meta-análise / Thermotherapy associated with flexibility training does not increase the knee range of movement of healthy adults: systematic review and meta-analysis of randomized clinical trials

The stretching with thermotherapies associated have been related in the literature as a way to increase the range of motion (ROM), but still are not consensus about this efficacy and costeffectiveness. The muscle stretching is a useful technique in rehabilitation and in physical activities programs, either to gain or maintain the flexibility, as a recovery of musculoskeletal and joint injuries. Objective: To determine the effects of thermotherapies associated to flexibility training in ROM of knee extension in healthy adults. Method: The search strategy was conducted in main databases, as Cochrane Library, LILACS, PEDro, PUBMED/ Medline, Scopus and Web of Science. The searches were done in 2016, and renewed in 2023, in order to achieve new publications along this time. Were selected only randomized clinical trials that have executed a training of hamstrings stretching, associated or not with one or more thermotherapies in healthy young adults, as long as the outcome was knee extension ROM. Only papers in Portuguese or English were assessed. To evaluate risk of bias was used the Cochrane Collaboration's Risk of Bias Tool, and the methodological quality assessment was rated following the PEDro Scale. Results: Eight articles were included, totalizing 260 participants. The papers showed low methodological quality, and uncertain risk of bias. Only chronic effect of local warming and cryotherapy plus stretching showed a statistically significant difference versus control group. However, the thermotherapy action associated with stretching is still unclear, once the results suggest that even without the thermotherapy there are ROM increases. Conclusion: The stretching is effective in knee extension ROM improvement in healthy adults, with or without thermotherapy. New studies with higher methodological rigor and standardized protocols are needed

Os alongamentos com termoterapias associadas têm sido relatados na literatura como forma de aumentar a amplitude de movimento (ADM), mas ainda não há consenso sobre sua eficácia e custo-efetividade. O alongamento muscular é uma técnica útil na reabilitação e em programas de atividades físicas, tanto para ganho ou manutenção da flexibilidade, quanto para recuperação de lesões musculoesqueléticas e articulares. Objetivo: Determinar os efeitos das termoterapias associadas ao treinamento de flexibilidade na ADM de extensão do joelho em adultos saudáveis. Método: A estratégia de busca foi realizada nas principais bases de dados, como Cochrane Library, LILACS, PEDro, PUBMED/ MedLine, Scopus e Web of Science. As buscas foram realizadas em 2016, e renovadas em 2023, a fim de alcançar novas publicações ao longo deste tempo. Foram selecionados apenas ensaios clínicos randomizados que tenham executado um treinamento de alongamento de isquiotibiais, associado ou não a uma ou mais termoterapias, em adultos jovens saudáveis, desde que o desfecho fosse ADM de extensão de joelho. Apenas artigos em português ou inglês foram avaliados. Para avaliar o risco de viés foi usado o Risk of Bias Tool da Cochrane Collaboration, e a avaliação da qualidade metodológica foi classificada de acordo com a Escala PEDro. Resultados: Foram incluídos oito artigos, totalizando 260 participantes. Os artigos apresentaram baixa qualidade metodológica e risco incerto de viés. Apenas o efeito crônico de aquecimento local e crioterapia associados ao alongamento mostrou uma diferença estatisticamente significativa em relação ao grupo controle. No entanto, a ação da termoterapia associada ao alongamento ainda não está clara, uma vez que os resultados sugerem que mesmo sem a termoterapia há aumento da ADM. Conclusão: O alongamento é eficaz na melhora da ADM de extensão do joelho em adultos saudáveis, com ou sem termoterapia. Novos estudos com maior rigor metodológico e protocolos padronizados são necessários

The effect of different exercise programs on sarcopenia criteria in older people: A systematic review of systematic reviews with meta-analysis.

OBJECTIVE: To compare the results of different modalities of physical exercises on the sarcopenia diagnostic criteria in older people. METHODS: Systematic review of systematic reviews. Search strategy included older people and sarcopenia MeSh, performed at mainly databases. Selected studies include older adults, submitted to physical training (Intervention Group: IG) compared to control groups (CG). Quantitative analyses with the inverse variance statistic method (random effects). The effect measures mean difference. Heterogeneity measured with Q-Test. RESULTS: 494 systematic reviews found. After screening, 5 were included (48 papers. n=3,877). Mean age: 74.02±6.1. 73.44% female. Mean interventions duration: 17.38 weeks (average: 2.56 weekly sessions). AMSTAR and PRISMA showed high methodological quality. Meta-analyses compared results of resistance training interventions (RTA) with other than resistance (Non-resistance Training interventions: NRTA). Handgrip strength, skeletal muscle mass (SMM) and gait speed showed statistically significant differences (SSD) favorable to IG. In chair stand test, RTA showed SSD favorable to the IG, and NRTA to CG. The timed-up-and-go do not showed SSD. DISCUSSION: The SMM and strength showed better results in RTA, although the confidence intervals (CI) overlap. Both valences can be trained with similar volume and training intensity, which can modify muscle volume and strength. Physical performance obtained better results in NRTA, even with CI overlap. For severely sarcopenic, training including more than one valence may be best. In sarcopenia diagnosis most studies do not take into account the consensuses of standardization, making hard the larger groups analysis. CONCLUSION: Being part of any training program can be beneficial for sarcopenia in older people, with resistance training better for strength and SMM, and mixed modalities for physical performance.

Conocimientos de padres y aceptabilidad para que sus hijos reciban la vacuna contra la COVID-19 / Parental knowledge and Approval for their Children to Receive COVID-19 Vaccine

Introducción: El análisis del riesgo-beneficio de la vacuna contra la COVID-19 en niños resulta desafiante por los efectos relativos de esta vacuna. Por ende, la decisión de vacunar a los niños recae en los padres. Objetivo: Evaluar la asociación entre los conocimientos de los padres y la aceptabilidad para que sus hijos recibían la vacuna contra la COVID-19. Métodos: Estudio observacional de diseño transversal y analítico con una población de 270 padres de alumnos de una institución educativa primaria de Lima, realizado en el período 2021-2022. Se utilizó un cuestionario para medir los conocimientos de la vacuna contra la COVID-19, una pregunta para evaluar la aceptabilidad de los padres de esta vacuna para sus hijos y una ficha de datos para medir las características de los padres. En el análisis estadístico se consideró una regresión logística binaria y multivariada. Resultados: El 79,63 por ciento de los padres aceptó la vacuna contra la COVID-19 para sus hijos y el 69,26 por ciento conocía de esta vacuna. Además, se demostró que el conocimiento se asoció con la aceptabilidad de la vacuna contra COVID-19 (PRa:1,22; IC:1,08-1,37; p = 0,001). Conclusiones: La mayoría de los padres poseía conocimientos sobre la vacuna contra la COVID-19 y gran parte de ellos aceptaron que sus hijos se vacunaran. Además, los padres que manifestaron más conocimientos sobre la COVID-19 aceptaron que sus hijos se vacunaran. Se recomienda que el personal de salud promueva información segura para que los padres tomen decisiones adecuadas(AU)

Introduction: Risk-benefit analysis of the COVID-19 vaccine in children is challenging because of the relative effects of this vaccine. Therefore, the decision to vaccinate children rests with the parents. Aim: To assess the association between parental knowledge and acceptability for their children to receive the COVID-19 vaccine. Methods: Observational study of cross-sectional and analytical design with a population of 270 parents of students from a primary school in Lima, conducted in the period 2021-2022. A questionnaire was used to measure knowledge of the COVID-19 vaccine, a question to assess parental acceptability of this vaccine for their children and a data sheet to measure parental characteristics. Binary and multivariate logistic regression was considered in the statistical analysis. Results: 79.63 percent of parents accepted the COVID-19 vaccine for their children and 69.26 percent were aware of this vaccine. Furthermore, knowledge was shown to be associated with acceptability of COVID-19 vaccine (PRa:1.22, CI:1.08-1.37, p = 0.001). Conclusions: The majority of parents were knowledgeable about the COVID-19 vaccine and a large proportion of them accepted their children to be vaccinated. In addition, parents who were more knowledgeable about COVID-19 were more willing to have their children vaccinated. It is recommended that health personnel promote safe information for parents to make proper decisions(AU)

There is no correlation between stages of nafld assessed by liver biopsy and the diagnostic criteria for sarcopenia in active populations: a cross-sectional study / Não há correlação entre os estágios da dhgna avaliados por biópsia hepática e os critérios diagnósticos para sarcopenia em populações ativas: um estudo transversal / No existe correlación entre las etapas de ehgna evaluadas mediante biopsia hepática y los criterios diagnósticos de sarcopenia en poblaciones activas: un estudio transversal

Objective: To demonstrate the correlations of the diagnostic criteria for sarcopenia and the levels of Non-alcoholic Fat Liver Disease (NAFLD) assessed by liver biopsy in a physically active population. Methods: Cross-sectional study. Individuals aged >18 years, with NAFLD confirmed by liver biopsy, physically active. Sarcopenia assessment followed EWGSOP2: muscle strength by handgrip, Skeletal Muscle Mass by Bioimpedance, and physical performance by usual gait speed. Statistical Analysis: To test differences between groups in continuous variables, Student's T or Mann-Whitney U Test for independent samples. Pearson and Spearman tests were used for correlations. A 5% significance was considered (p<0.05). Results: 52 patients with NAFLD included, consisting of 35 women and 15 men. There was no difference in age or anthropometric variables. Were found difference statically significant in platelets (higher in women), basal insulin, HOMA-IR and Quick (higher in men). In sarcopenia, the handgrip strength showed difference in favors of men. There was no statistically significant correlation between the sarcopenia and NAFLD levels. Discussion: sarcopenia has been reported as an independent risk factor for NAFLD and its progressions. The physical exercise is one of the most recommended and more effective treatment for both conditions, so is expected that a non-sedentary individual can reduce both indicators. However, there is no consensus about the best method. Also, the both conditions share heterogeneity in diagnosis, prognosis, reason for develop and risk factors across the literature. Conclusion: For populations where most individuals are physically active, it is not possible to find correlation between sarcopenia diagnostic criteria and the stages of NAFLD.

Objetivo: Demonstrar as correlações dos critérios diagnósticos de sarcopenia e dos níveis de doença hepática gordurosa não alcoólica (DHGNA) avaliados por biópsia hepática em uma população fisicamente ativa. Métodos: Estudo transversal. Indivíduos com idade >18 anos, com DHGNA confirmada por biópsia hepática, fisicamente ativos. A avaliação da sarcopenia seguiu o EWGSOP2: força muscular por preensão manual, massa muscular esquelética por bioimpedância e performance física por velocidade usual de marcha. Análise Estatística: Para testar diferenças entre grupos nas variáveis contínuas, teste T de Student ou Teste U de Mann-Whitney para amostras independentes. Os testes de Pearson e Spearman foram utilizados para correlações. Foi considerada significância de 5% (p<0,05). Resultados: Foram incluídos 52 pacientes com DHGNA, sendo 35 mulheres e 15 homens. Não houve diferença na idade ou nas variáveis antropométricas. Foram encontradas diferenças estatisticamente significativas em plaquetas (maior em mulheres), insulina basal, HOMA-IR e Quick (maior em homens). Na sarcopenia, a força de preensão manual apresentou diferença em favor dos homens. Não houve correlação estatisticamente significativa entre os níveis de sarcopenia e DHGNA. Discussão: a sarcopenia tem sido relatada como fator de risco independente para DHGNA e suas progressões. O exercício físico é um dos tratamentos mais recomendados e mais eficazes para ambas as condições, pelo que se espera que um indivíduo não sedentário consiga reduzir ambos os indicadores. No entanto, não há consenso sobre o melhor método. Além disso, ambas as condições compartilham heterogeneidade no diagnóstico, prognóstico, razão de desenvolvimento e fatores de risco em toda a literatura. Conclusão: Para populações onde a maioria dos indivíduos é fisicamente ativo, não é possível encontrar correlação entre os critérios diagnósticos de sarcopenia e os estágios da DHGNA.

Objetivo: demostrar las correlaciones de los criterios diagnósticos de sarcopenia y los niveles de enfermedad del hígado graso no alcohólico (EHGNA) evaluados mediante biopsia hepática en una población físicamente activa. Métodos: Estudio transversal. Individuos mayores de 18 años, con EHGNA confirmada mediante biopsia hepática, físicamente activos. La evaluación de la sarcopenia siguió el EWGSOP2: fuerza muscular mediante agarre manual, masa muscular esquelética mediante bioimpedancia y rendimiento físico mediante velocidad de marcha habitual. Análisis estadístico: Para probar diferencias entre grupos en variables continuas, prueba T de Student o U de Mann-Whitney para muestras independientes. Para las correlaciones se utilizaron las pruebas de Pearson y Spearman. Se consideró una significancia del 5% (p<0,05). Resultados: Se incluyeron 52 pacientes con EHGNA, 35 mujeres y 15 hombres. No hubo diferencia en la edad ni en variables antropométricas. Se encontraron diferencias estadísticamente significativas en plaquetas (mayor en mujeres), insulina basal, HOMA- IR y Quick (mayor en hombres). En la sarcopenia, la fuerza de prensión manual mostró diferencia a favor de los hombres. No hubo correlación estadísticamente significativa entre la sarcopenia y los niveles de NAFLD. Discusión: la sarcopenia ha sido reportada como un factor de riesgo independiente para NAFLD y sus progresiones. El ejercicio físico es uno de los tratamientos más recomendados y efectivos para ambas afecciones, por lo que se espera que una persona no sedentaria pueda reducir ambos indicadores. Sin embargo, no hay consenso sobre cuál es el mejor método. Además, ambas afecciones comparten heterogeneidad en el diagnóstico, pronóstico, motivo de desarrollo y factores de riesgo en la literatura. Conclusión: Para poblaciones donde la mayoría de las personas son físicamente activas, no es posible encontrar correlación entre los criterios de diagnóstico de sarcopenia y las etapas de NAFLD.

Comparison of diagnosis frequency between versions of the European Consensus on Sarcopenia: a cross-sectional study / Comparação da frequência de diagnóstico entre as versões do Consenso Europeu sobre Sarcopenia: um estudo transversal

OBJECTIVE: To compare sarcopenia diagnosis according to 2 versions of the European Consensus on Sarcopenia (EWGSOP and EWGSOP2) in a sample of older adults. METHOD: This cross-sectional study included 82 community-dwelling older people from Porto Alegre, Brazil. The patients were assessed by trained professionals and were classified according to the criteria of the 2 versions of the consensus to show the differences between the classification models. RESULTS: The participants performed the Timed Up and Go test in < 7.21 seconds. On average, their performance on the 6-meter walk test was above the predicted value. Only 3 patients had a gait speed < 0.8 m/s. Handgrip strength was, on average, the predicted percentage. In the Short Physical Performance Battery, the scores of a few were intermediate but most were high. According to EWGSOP criteria, 92.18% were non-sarcopenic and 7.81% had severe sarcopenia, while according to EWGSOP2 criteria, 98.43% were non-sarcopenic, 1.56% were sarcopenic, and none had severe sarcopenia. The rate of sarcopenia diagnosis, which was 8.53% according to EWGSOP criteria, reduced to 3.65% according to EWGSOP2 criteria and the new cut-off points (p = 0.034). CONCLUSION: Although our sample was small, the reduction was significant, indicating that the change in criteria, even with lower cut-off points, reduced the probability of early diagnosis

OBJETIVO: Comparar a aplicação dos critérios e orientações das duas versões do Consenso Europeu sobre Sarcopenia (EWGSOP e EWGSOP2) para o diagnóstico e classificação, numa amostra de idosos residentes na comunidade. METODOLOGIA: Estudo transversal, com 82 idosos residentes na comunidade da cidade de Porto Alegre. Os pacientes foram avaliados por profissionais treinados e classificados segundo os critérios dos dois consensos para mostrar as diferenças entre os dois modelos de classificação.RESULTADOS: Em testes físicos como o timed up and go, a amostra realizou o teste em menos de 7,21 segundos. Em média, os idosos conseguiram caminhar no teste de caminhada de 6 metros mais do que a percentagem prevista para esse público. Apenas três pacientes apresentaram velocidade de caminhada inferior a 0,8 m/s. Na avaliação de força, os idosos conseguiram atingir, em média, o percentual previsto. No Short Physical Performance Battery, poucos tiveram desempenho intermediário. A maioria teve desempenho alto. Quando avaliados pelo EWGSOP, 92,18% eram não sarcopênicos, enquanto 7,81% eram sarcopênicos severos; e, quando avaliados pelo EWGSOP2, 98,43% eram não sarcopênicos, 1,56% sarcopênico e nenhum sarcopênico severo. A aplicação dos critérios EWGSOP2 e novos pontos de corte reduziram a capacidade de diagnóstico de sarcopenia na amostra de 8,53 para 3,65% (p = 0,034).CONCLUSÃO: Embora a amostra seja pequena, a redução é significativa e expressa que a mudança de critério, mesmo utilizando pontos de corte mais baixos para a amostra em análise, trouxe impacto no sentido de não diagnosticar precocemente

Biomechanics of anterior endocrowns with different designs and depths: Study of finite elements.

Background: To date, there is no clear consensus in the literature on which endocrown design and depth is the most effective treatment option for restoring endodontically treated maxillary central incisors. Aim: To determine the stress distribution of the anterior endocrowns by means of finite element analysis. Material and Methods: Nine 3D finite element models (groups A - I) were made, each one representing a restoration system of endodontically treated upper central incisors. The models were endocrowns with and without ferrules at 0, 1, 3, and 5 mm depth and a post-core stump control group. A static load of 100N of force was applied to the palatal face at 45º from the long axis of the tooth. The Von Mise values and the maximum stress in the crown, dentin and resin cementum were evaluated separately. Results: The maximum stress distribution was C < B < A < D < H < F < E < G < I and the Von Mises stresses were in the upper 1/3 of the retainer of endocrowns A, B, C and D. ; in the vestibular neck in endocrowns E and F; in the final 1/3 of the retainer in the endocrown G; in the middle 1/3 of the retainer in the H endocrown; and at the level of the vestibular neck of the crown in model I. Conclusions: The smallest distribution of maximum and Von Mises stresses was observed in model C. Key words:Finite element analysis, Biomechanics, upper central incisor, endodontically treated teeth, dental restoration.

Knee Isokinetic Profiles and Reference Values of Professional Female Soccer Players.

Few studies have previously evaluated isokinetic parameters in female soccer players in comparison to those in males. The aim of this study was to describe normative quadriceps (Q) and hamstring (H) muscle strength values in professional female soccer players and to examine differences between dominant leg (DL) and nondominant leg (NDL). A standardized test protocol of concentric knee extension and flexion test protocol was conducted using the dynamometer isokinetic system (IsoMEd 2000). All the participants were healthy female professional soccer players from Spanish first and second division teams. Players were assessed for peak torque (PT) and maximum work (MW) values at 60°/s, 180°/s, and 240°/s. The mean difference was 7.17 (p-value = 0.0036), 4.4 (p-value = 0.0386), and 4.25 Nm (p-value = 0.0241) at speed 60°, 180°, and 240°/s, respectively. No statistically significant differences were detected for H-Q values between DL and NDL. This difference was 6.44 (p-value = 0.0449), and 5.87 J (p-value = 0.0266) at speed 60°, and 180°/s. The present study can be a tool that health professionals working with female professional soccer players in their care can use to assess and monitor a particular player.

Blood Pressure and Heart Rate Responses to an Isokinetic Testing Protocol in Professional Soccer Players.

The aim of this study was to determine blood pressure (BP) and heart rate (HR) responses triggered during an isokinetic testing protocol in professional soccer players and compare cardiovascular parameters at completion of this isokinetic protocol with those during a treadmill test. Using purposive sampling, 63 professional soccer players were recruited. Cardiovascular responses were measured noninvasively during a bilateral testing protocol of knee flexion and extension. Treadmill ergospirometry following an incremental speed protocol was performed to analyze the same cardiovascular parameters at rest and at completion of this test. There were significant differences in diastolic blood pressure (DBP) and HR according to field position. The parameters presented high homogeneity at both competitive levels. Systolic blood pressure, mean arterial pressure, HR, and rate pressure product at completion of the treadmill test were significantly higher than those at completion of the isokinetic protocol. Intermittent isokinetic testing protocol of the knee triggers normal and safe BP and HR responses in healthy professional soccer players. The HR of the defenders was higher than those of the forwards and midfielders but was independent of the competitive level. The values of cardiovascular parameters at isokinetic protocol completion were lower than those during the treadmill test.

Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing.

Cardiosphere-derived cells (CDCs) generated from human cardiac biopsies have been shown to have disease-modifying bioactivity in clinical trials. Paradoxically, CDCs' cellular origin in the heart remains elusive. We studied the molecular identity of CDCs using single-cell RNA sequencing (sc-RNAseq) in comparison to cardiac non-myocyte and non-hematopoietic cells (cardiac fibroblasts/CFs, smooth muscle cells/SMCs and endothelial cells/ECs). We identified CDCs as a distinct and mitochondria-rich cell type that shared biological similarities with non-myocyte cells but not with cardiac progenitor cells derived from human-induced pluripotent stem cells. CXCL6 emerged as a new specific marker for CDCs. By analysis of sc-RNAseq data from human right atrial biopsies in comparison with CDCs we uncovered transcriptomic similarities between CDCs and CFs. By direct comparison of infant and adult CDC sc-RNAseq data, infant CDCs revealed GO-terms associated with cardiac development. To analyze the beneficial effects of CDCs (pro-angiogenic, anti-fibrotic, anti-apoptotic), we performed functional in vitro assays with CDC-derived extracellular vesicles (EVs). CDC EVs augmented in vitro angiogenesis and did not stimulate scarring. They also reduced the expression of pro-apoptotic Bax in NRCMs. In conclusion, CDCs were disclosed as mitochondria-rich cells with unique properties but also with similarities to right atrial CFs. CDCs displayed highly proliferative, secretory and immunomodulatory properties, characteristics that can also be found in activated or inflammatory cell types. By special culture conditions, CDCs earn some bioactivities, including angiogenic potential, which might modify disease in certain disorders.

A Method for Determination of the Transmission Efficiency of a Silica Optical Fiber Cable Using a Solar Power Tower.

After being adequately captured and concentrated, solar radiation can be conducted by optical fiber bundles/cables and directly used for illumination (lighting) or heating of confined spaces, or indirectly used by converting it in other forms of energy (e.g., for producing electricity). This article reports preliminary tests conducted on a 7-m-long optical fiber bundle/cable with an effective aperture circular area of 14 mm in diameter, specially designed and manufactured by a leading company to transmit up to 1000 Wth of unfiltered concentrated sunlight. The cable was tested in the typical receiver position at the top of a solar concentration central tower. The main purpose was the experimental determination of the transmission efficiency of the cable in function of the incidence angle using selected groups of heliostats belonging to the heliostat field. The testing methodology proved to be capable of evaluating the performance of the cable. The cable withstood the tests without revealing any type of damage. The results obtained showed that the transmissivity of the cable is higher than 50% when the incidence angle of the solar radiation is lower than 14.7°, increasing sharply to circa 95% when the incidence angle is lower than 4.5°.

Sexual dysfunctions in female university students and the correlation with body image: a cross-sectional study.

PURPOSE: This study aims to correlate female sexual dysfunctions and dissatisfaction with female university students' body image. METHODS: 276 female university students completed an online questionnaire, including sociodemographic data, the Female Sexual Function Index, and the Body Shape Questionnaire. RESULTS: 31.1% reported some degree of dissatisfaction with body image, and 39.5% had a risk of female sexual dysfunction. The majority of women with a risk of female sexual dysfunctions (69.4%) had no concerns with shape, and the majority of women without sexual problems (67.7%) had no concerns with shape. Pearson's coefficient underlined no correlation between Body Shape Questionnaire and Female Sexual Function Index domains. CONCLUSION: The body image perception did not seem to affect the sexual function of female university students in our sample. However, it is important to further investigate these variables to improve women's quality of life.

Isokinetic profiles and reference values of professional soccer players / Perfil isocinético y valores de referencia de futbolistas profesionales / Perfis isocinéticos e valores de referência dos jogadores de futebol profissional

ABSTRACT Introduction: Isokinetics is a tool commonly used in professional soccer. There is ongoing debate among researchers as to the isokinetic reference values a player should have. Objectives: To determine the absolute peak torque (PT) and average work of professional soccer players in relation to their positions on the field, and to establish the reference values for these variables. Methods: Purposeful sampling was used to select 289 professional soccer players. The sample included 32 goalkeepers, 100 defenders, 98 midfielders, and 59 strikers. The participants were measured preseason. The players were asked to perform a 10-minute warm-up on an exercise bike, and then to perform 5 repetitions at low speed, 10 at medium speed, and 25 at high speed, with 30 to 40-s of rest between each set of repetitions. The contraction method was concentric-concentric in a dynamometer Isomed 2000. Results: The average age, weight, and height of the players was 21.9 years, 74.3 kilograms, and 1.8 meters, respectively. The goalkeepers presented higher PT at the 3 measured speeds, and the higher average work at 180°/s and 240°/s in relation to defenders and midfielders. The strikers presented higher average work at 240°/s in relation to midfielders, and higher PT in relation to the defenders and midfielders. Absolute values were shown and reference values were established. Conclusions: The goalkeepers and strikers were the players that showed the greatest differences in their favor in relation to the other positions. The peak torque values and average work were described in relation to the player's position on the field. This study resulted in the creation of a tool for health professionals working with professional soccer players, providing reference values for these players in relation to their position on the field that can be used as benchmarks, by health professionals, to optimize soccer players' performance. Level of evidence II, Prospective comparative study.

RESUMEN Introducción: La evaluación isocinética es una herramienta de uso común en el fútbol profesional. Sigue existiendo debate entre los investigadores sobre los valores isocinéticos de referencia que debe tener un jugador. Objetivos: Determinar el torque máximo (TM) y el trabajo promedio de los futbolistas profesionales en relación a sus posiciones en el campo y establecer los valores de referencia para estas variables. MÉTODOS: Se seleccionó una muestra subjetiva de 289 futbolistas profesionales. Se incluyeron 32 porteros, 100 defensas, 98 centrocampistas y 59 delanteros. Los participantes fueron examinados en la pretemporada. Se solicitó a los participantes que realizaran un calentamiento de 10 minutos en bicicleta estática y luego realizar 5 repeticiones a baja velocidad, 10 a velocidad media y 25 a alta velocidad con 30 a 40 segundos de descanso entre cada serie de repeticiones. El método de contracción fue concéntrico-concéntrico en dinamómetro Isomed 2000. Resultados: La edad, el peso y la altura promedios de los jugadores fue de 21,9 años, 74,3 kilogramos y 1,8 metros, respectivamente. Los porteros presentaron TM más elevado en las 3 velocidades medidas y un mayor trabajo promedio a 180°/s y 240°/s en relación a defensas y centrocampistas. Los delanteros presentaron un mayor trabajo promedio a 240°/s en relación con los centrocampistas y TM más elevado en relación a defensas y centrocampistas. Se mostraron los valores absolutos y se establecieron los valores de referencia. Conclusiones: Los porteros y delanteros fueron los que mostraron mayores diferencias a su favor en relación al resto. Los valores de torque máximo y el trabajo promedio fueron descritos en relación a la posición del jugador en el campo. Los resultados del presente estudio son una herramienta para los profesionales de la salud que trabajan con futbolistas profesionales y proporcionó valores de referencia para estos futbolistas en lo que respecta a su posición que pueden utilizarse como referencia para optimizar el rendimiento. Nivel de evidencia II, Estudio comparativo retrospectivo.

RESUMO Introdução: A isocinética é uma ferramenta comum usada no futebol profissional. Entre os pesquisadores, há um debate contínuo sobre os valores isocinéticos de referência que um jogador deve ter. Objetivos: Determinar o pico de torque (PT) absoluto e o trabalho médio de jogadores de futebol profissional com relação às posições em campo e estabelecer os valores de referência para essas variáveis. MÉTODOS: Foi selecionada uma amostra subjetiva de 289 jogadores de futebol profissional. A amostra incluiu 32 goleiros, 100 zagueiros, 98 meio-campistas e 59 atacantes. Os participantes foram testados na pré-temporada. Os participantes foram solicitados a realizar aquecimento de 10 minutos em bicicleta ergométrica e, a seguir, realizar cinco repetições em baixa velocidade, 10 em velocidade média e 25 em alta velocidade com 30 a 40 segundos de descanso entre cada série de repetições. O método de contração foi concêntrico-concêntrico em um dinamômetro Isomed 2000. Resultados: A média de idade, peso e estatura dos jogadores foi de 21,9 anos, 74,3 quilos e 1,8 metros, respectivamente. Os goleiros apresentaram maior PT nas três velocidades medidas e maior média de trabalho a 180°/s e 240°/s com relação aos zagueiros e meio-campistas. Os atacantes tiveram maior trabalho médio a 240°/s com relação aos meio-campistas e maior PT com relação aos zagueiros e meio-campistas. Os valores absolutos foram mostrados e os valores de referência foram estabelecidos. Conclusões: Os goleiros e atacantes apresentaram as maiores diferenças a seu favor com relação às demais posições. Os valores de pico de torque e trabalho médio foram descritos com relação à posição do jogador em campo. Este estudo resultou na criação de uma ferramenta para profissionais de saúde que atuam com jogadores de futebol profissional e forneceu valores de referência para esses jogadores com relação à posição em campo que podem ser usados como referência para otimizar o desempenho dos jogadores de futebol. Nível de evidência II, Estudo retrospectivo comparativo.

Numerical Simulation of the Hot Rolling Process of Steel Beams.

The complete rolling schedule (25 passes) of steel beams in a mill was simulated to predict the final beam length, geometry of the cross-section, effective stress, effective plastic strain and rolling power for two cases; the first case corresponds to the hot rolling process assuming a constant temperature of 1200 ∘C. The simulation of the second case considered the real beam temperature at each pass to compare the results with in-plant measurements and validate the numerical model. Then, the results of both cases were compared to determine the critical passes of the process with high peaks of required power, coinciding with the reports at the mill. These critical passes share the same conditions, high percentage of reduction in cross-sectional area and low beam temperature. Additionally, a potential reduction of passes in the process was proposed identifying passes with low required power, minimal reduction in area of cross-section and essentially unchanged geometry. Therefore, it is reasonable to state that using the present research methodology, it is possible to have a better control of the process allowing innovation in the production of profiles with more complex geometries and new materials.