Prevalence of chronic venous pathology in healthcare workers and the role of upright standing.

BACKGROUND: Chronic venous disease (CVD) affects around 25% of adult population in developed countries and it often represent a health problem for different kind of workers, in particular for who spend much of the working time in upright standing. METHODS: The study was carried out on a population of 173 nonmedical workers of a midsize hospital in Italy (91 nurse, 31 support staff workers and 51 employees). The study protocol was taken from a previous study of our group and included a clinical examination and a questionnaire. RESULTS: From the analysis of data it emerged a particular importance of upright standing as major risk factor for CVD. The prevalence of venous pathology seems to be greater among nurses and auxiliaries than the administrative staff and, as expected, it was significantly higher among female workers than in males. CONCLUSIONS: The results obtained show that the clinical-diagnostic protocol described can be used by doctors for screening venous pathology at workplaces.

No Correlation between Blood Benzene Levels and Luteinizing Hormone Plasma Values in Outdoor Workers.

OBJECTIVE: The purpose of the study is to evaluate whether low-dose exposure to benzene, an environmental pollutant to which male and female traffic policemen are daily exposed to could cause alterations in plasma luteinizing hormone (LH) levels. METHODS: From an initial sample of 1594 workers, we only selected 95 workers of whom study we knew the values of late-shift benzene and LH hormone. All subjects underwent biological monitoring (final blood benzene evaluation) and luteinizing hormone dosing. Excluding subjects with the main confounding factors, the final sample included 76 workers. The normal distribution of the variables was evaluated using the Kolmogorov - Smirnov test, followed by the logarithmic transformation of the LH and benzene values. The comparison among means was performed by using the t-test for the independent samples. The ANOVA test was performed for variables with more than 2 modes (ages and seniority) and Pearson correlation index between variables in the total sample and after subdivision as to sex, job, sports activity and smoking. The results were considered significant when p values were less than 0.05. RESULTS/CONCLUSION: The study did not show a correlation between benzene levels and LH plasma levels in outdoor workers.

Peripheral blood counts in workers exposed to synthetic fibres.

Acrylonitrile is an intermediary with possible adverse health effects in the synthesis of organic products, such as acrylic fibres. This investigation was undertaken to determine the possible changes in the peripheral blood counts in workers of a polyacrylic fibres plant. The study involved 218 workers exposed to acrylonitrile at low doses and a control group of 200 unexposed workers. The chosen subjects underwent blood tests in order to check their haematological parameters. There were no statistically significant differences between the two groups in terms of the red blood cells, haemoglobin and total number of leukocytes. An increase in the neutrophils associated with a reduction of lymphocytes, both statistically significant, was observed. The authors hypothesized that the neutrophils are influenced by the exposure to acrylonitrile at low doses.

Prolactin levels in workers exposed to chemical, physical and psycho-social urban stressors.

The aim of this study was to evaluate whether traffic police officers exposed to chemical, physical and psycho-social stressors, are at risk for alterations in plasma levels of prolactin (PRL) compared to a control group. Plasma PRL levels were evaluated in 92 male and 51 female, non-smoker, traffic police officers exposed to urban stressors and in 92 male and 51 female controls, matched by sex, age and working life (mean, SD and distribution), after excluding workers with the principal extra-occupational confounding factors. Mean PRL levels were significantly higher than controls in non-smoker, male and female traffic police officers (respectively, p=0.000 and p=0.013). The number of non-smoker, male and female traffic police officers with PRL values outside the upper normal limit for our laboratory was higher than, but not significantly different from controls. Mean PRL levels were not significantly higher than controls in smoker, male and female traffic police officers. The number of smoker, male and female traffic police officers with PRL values outside the normal limit for our laboratory was not significantly different from controls. The results suggest that exposure to urban chemical and physical stressors, interacting with psychosocial factors, may have an influence on PRL levels in traffic police officers. The level of plasma PRL might be a useful early biological marker for workers exposed to urban stressors.

Occupational exposure to urban pollutants and plasma insulin.

OBJECTIVE: The aim of this study was to investigate whether traffic police of a big city who are exposed to urban pollutants are at risk to alterations in plasma insulin concentrations compared with controls. METHODS: The class of workers examined in this study were employees of the municipal police in Rome, Italy. The study was carried out during the period March-April 2001. Traffic police were matched with a control group, where gender, age, working life and drinking habit were noted. A total of 246 traffic police (128 men and 118 women) with outdoor activity and exposure to urban pollutants and 242 subjects (128 men and 114 women) with indoor activity were included in the study. RESULTS: The levels of plasma insulin were significantly lower in traffic police compared to the control group of both gender. CONCLUSION: Plasma insulin level was altered in traffic police who are exposed to chemical and physical stressors.