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1.
Pediatr Radiol ; 51(11): 2047-2057, 2021 Oct.
Article in English | MEDLINE | ID: mdl-34009406

ABSTRACT

BACKGROUND: There is a paucity of literature describing MRI patterns of high ankle sprains in pediatric patients. Radiologists should understand MRI patterns of these injuries in both adults and children. OBJECTIVE: To describe normal MRI appearance of pediatric syndesmotic ligaments and compare MRI patterns of high ankle sprains in children versus adults. MATERIALS AND METHODS: We reviewed consecutive ankle MRIs performed over 3 years and divided them into three cohorts: a normal pediatric (≤16 years) cohort, and pediatric and adult cohorts with acute/subacute ankle syndesmosis injuries. Our retrospective review assessed interobserver agreement (Cohen kappa coefficient) and normal pediatric syndesmotic anatomy. We compared patterns of high ankle sprains (Fisher exact test) including ligament tears, periosteal stripping, avulsions and fractures. RESULTS: Of the 582 ankle MRIs, we included 25 in the normal pediatric cohort, 20 in the pediatric injury cohort and 23 in the adult injury cohort. The anterior and posterior tibiofibular ligaments all attached to cortex or cartilaginous precursor, while the interosseous ligament/membrane complex attached to the fibrous periosteum in 22/25 (88%) normal pediatric cases. Tibial periosteal stripping at the interosseous ligament/membrane complex attachment occurred in 7/20 (35%) pediatric and 1/23 (4%) adult injury cases (P=0.02). No other statistically significant differences were found. Interobserver agreement ranged from kappa=0.46 to kappa=0.82 (ligament tears), 0.38 to 0.45 (avulsions) and 0.69 to 0.77 (periosteal stripping). CONCLUSION: The normal interosseous ligament/membrane complex typically attaches to fibrous periosteum rather than bony cortex. Tibial periosteal stripping, usually without tibial fracture, is significantly more common among pediatric high ankle sprains. MRI patterns of high ankle sprains are otherwise not significantly different between children and adults.


Subject(s)
Ankle Injuries , Adult , Ankle Injuries/diagnostic imaging , Ankle Joint , Child , Humans , Ligaments, Articular/diagnostic imaging , Magnetic Resonance Imaging , Retrospective Studies
2.
Radiographics ; 41(1): 210-223, 2021.
Article in English | MEDLINE | ID: mdl-33216674

ABSTRACT

Normal skeletal development in the pediatric ankle is dynamic and often produces variable imaging appearances that are subject to misinterpretation. Radiologists must understand the underlying developmental phenomena, such as endochondral and membranous ossification and physeal fusion, and be familiar with their common and uncommon imaging manifestations unique to the pediatric ankle. This is especially true as the use of MRI in the evaluation of musculoskeletal trauma expands among younger populations. The authors focus on MRI evaluation of the skeletally maturing pediatric ankle and present pearls for accurately distinguishing normal findings and imaging pitfalls from true pathologic findings. The normal but often variable imaging findings of preossification, secondary ossification, and multiple ossification centers, as well as the range of bone marrow signal intensities that can be visualized within ossification centers, are described, along with tips to help differentiate these from true pathologic findings such as contusion, fracture, or tumor. The authors also review dynamic periosteal and physeal contributions to bone growth to highlight helpful distinguishing features and avoid misdiagnosis of common subperiosteal and periphyseal abnormalities. For example, the normal trilaminar appearance of the immature cortex and periosteum should not be mistaken for periosteal reaction, traumatic stripping, or subperiosteal hematoma. In addition, the physis can have several confusing but normal appearances, including normal physeal undulations (eg, Kump bump) or focal periphyseal edema, which should not be mistaken for pathologic findings such as physeal fracture, infection, or bar. ©RSNA, 2020.


Subject(s)
Ankle , Bone Diseases , Child , Edema , Growth Plate , Humans , Magnetic Resonance Imaging
3.
Radiographics ; 39(1): 136-152, 2019.
Article in English | MEDLINE | ID: mdl-30500305

ABSTRACT

The midtarsal (Chopart) joint complex consists of the talonavicular and calcaneocuboid joints and their stabilizing ligaments. Detailed assessment of this complex at MRI can be challenging owing to frequent anatomic variation and the small size of the structures involved. Nevertheless, a wide spectrum of pathologic conditions affect the joint complex, and its imaging evaluation deserves more thorough consideration. This review focuses on MRI evaluation of normal ligamentous anatomy and common variations about the Chopart joint, presenting practical imaging tips and potential diagnostic pitfalls. Imaging findings across a spectrum of traumatic Chopart joint injuries are also reviewed, from midtarsal sprains to Chopart fracture-dislocations. Midtarsal sprains-commonly associated with ankle inversion injuries-are emphasized, along with their often predictable radiographic and MRI injury patterns. Online DICOM image stacks are available for this article. ©RSNA, 2018.


Subject(s)
Fractures, Bone/diagnostic imaging , Magnetic Resonance Imaging/methods , Sprains and Strains/diagnostic imaging , Tarsal Joints/anatomy & histology , Tarsal Joints/injuries , Biomechanical Phenomena , Female , Humans , Male , Osteoarthritis/diagnostic imaging , Tarsal Joints/diagnostic imaging , Tomography, X-Ray Computed
4.
AJR Am J Roentgenol ; 211(2): 416-425, 2018 08.
Article in English | MEDLINE | ID: mdl-29927330

ABSTRACT

OBJECTIVE: The objective of this article is to review the normal anatomy and posttraumatic findings of the Chopart joint complex. Key imaging features of the normal ligaments and patterns of ligamentous and osseous injuries are discussed. CONCLUSION: Traumatic midtarsal injuries, particularly midtarsal sprain, are often overlooked clinically and on imaging but are relatively common and typically are associated with inversion ankle injuries. Radiologists should be familiar with Chopart joint anatomy and the imaging features of midtarsal injuries because early diagnosis may help optimize clinical management.


Subject(s)
Ankle Injuries/diagnostic imaging , Ligaments, Articular/anatomy & histology , Ligaments, Articular/injuries , Sprains and Strains/diagnostic imaging , Tarsal Joints/anatomy & histology , Tarsal Joints/injuries , Humans
5.
AJR Am J Roentgenol ; 210(5): 1123-1130, 2018 May.
Article in English | MEDLINE | ID: mdl-29570372

ABSTRACT

OBJECTIVE: Injuries at the calcaneocuboid and talonavicular joint have been described as two distinct, unrelated entities in the radiology literature. Our purpose was to assess the coexistence of these injuries using radiography and MRI and to correlate our findings with radiologic and clinical diagnoses. MATERIALS AND METHODS: Twenty-one patients with injury at the anterior calcaneal process on radiographs or MR images were retrospectively assessed for concomitant injury at the talonavicular joint. Radiologic and clinical diagnoses and treatment were documented. McNemar and kappa statistics were calculated; p values < 0.05 were considered statistically significant. RESULTS: Radiographic and MRI rates of detection of injuries across the Chopart joint were statistically different. Calcaneocuboid avulsion fractures were evident on 48% of radiographs and 100% of MR images (p = 0.001). Talonavicular joint injuries were evident on 38% of radiographs and 76% of MR images (p = 0.008). Concomitant injury at both joints was evident on 14% of radiographs and 76% of MR images (p < 0.0001). Interrater agreement was 0.488-0.637 and 0.286-0.364 for talonavicular and 0.144-0.538 and 0.976-1 for calcaneocuboid injuries on radiography and MRI, respectively. Sixty percent of calcaneocuboid fractures were prospectively missed on radiography (none on MRI), whereas 38% and 25% of talonavicular findings were missed on radiography and MRI, respectively. Sixty percent of injuries were clinically misdiagnosed as ankle sprains. Chopart joint injury was never mentioned in prospective clinical or imaging diagnoses. CONCLUSION: Calcaneocuboid and talonavicular injuries commonly coexist. Radiographs underestimate severity of injury; MR images show more subtle abnormalities. Lack of mention of Chopart joint injury clinically and on imaging reports underlies the need for greater familiarity with this entity.


Subject(s)
Calcaneus/diagnostic imaging , Calcaneus/injuries , Fractures, Bone/diagnostic imaging , Tarsal Joints/diagnostic imaging , Tarsal Joints/injuries , Adult , Aged , Aged, 80 and over , Female , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Retrospective Studies
6.
AJR Am J Roentgenol ; 210(2): 386-395, 2018 Feb.
Article in English | MEDLINE | ID: mdl-29112474

ABSTRACT

OBJECTIVE: This study determined the frequency and MRI appearance of osseous and ligamentous injuries in midtarsal (Chopart) sprains and their association with ankle sprains after acute ankle injuries. Prospective diagnosis of and interobserver agreement regarding midtarsal injury among musculoskeletal radiologists were also assessed. SUBJECTS AND METHODS: Two cohorts with ankle MRI were identified via a digital PACS search: patients who had undergone MRI within 8 weeks after ankle injury and control subjects who had not sustained ankle trauma. Studies were retrospectively reviewed in consensus as well as independently, assessing ligamentous and osseous injury to the Chopart joint (calcaneocuboid and talonavicular joints) and associated lateral collateral and deltoid ligamentous injury. Interobserver agreement was calculated, and prospective radiology reports were reviewed to determine the musculoskeletal radiologist's familiarity with Chopart joint injury. RESULTS: MR images of control subjects (n = 16) and patients with ankle injury (n = 47) were reviewed. The normal dorsal calcaneocuboid and calcaneocuboid component of bifurcate ligaments were variably visualized; the remaining normal ligaments were always seen. Eleven patients (23%) had midtarsal ligamentous and osseous injury consistent with midtarsal sprain (eight acute or subacute, one probable, and two old). Six (75%) of eight acute or subacute cases had coexisting lateral collateral ligament injury. Eighty-nine percent of osseous injuries were reported prospectively, but 83% of ligamentous injuries were missed. Substantial interobserver agreement was achieved regarding diagnosis of midtarsal sprain. CONCLUSION: Midtarsal sprains are commonly associated with acute ankle injury and with ankle sprains. Presently, midtarsal sprains may be underrecognized by radiologists; thus, greater familiarity with the MRI spectrum of ligamentous and osseous injuries at the Chopart joint is important for accurate diagnosis and clinical management.


Subject(s)
Ankle Injuries/diagnostic imaging , Magnetic Resonance Imaging/methods , Sprains and Strains/diagnostic imaging , Adult , Case-Control Studies , Female , Humans , Male , Retrospective Studies
7.
J Am Coll Radiol ; 14(5S): S189-S202, 2017 May.
Article in English | MEDLINE | ID: mdl-28473075

ABSTRACT

Osteoporosis is a considerable public health risk, with 50% of women and 20% of men >50 years of age experiencing fracture, with mortality rates of 20% within the first year. Dual x-ray absorptiometry (DXA) is the primary diagnostic modality by which to screen women >65 years of age and men >70 years of age for osteoporosis. In postmenopausal women <65 years of age with additional risk factors for fracture, DXA is recommended. Some patients with bone mineral density above the threshold for treatment may qualify for treatment on the basis of vertebral body fractures detected through a vertebral fracture assessment scan, a lateral spine equivalent generated from a commercial DXA machine. Quantitative CT is useful in patients with advanced degenerative bony changes in their spines. New technologies such as trabecular bone score represent an emerging role for qualitative assessment of bone in clinical practice. It is critical that both radiologists and referring providers consider osteoporosis in their patients, thereby reducing substantial morbidity, mortality, and cost to the health care system. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.


Subject(s)
Absorptiometry, Photon/methods , Bone Density , Osteoporosis/diagnostic imaging , Aged , Female , Femur/diagnostic imaging , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Osteoporosis/complications , Risk Factors , Spinal Fractures/diagnostic imaging , Tomography, X-Ray Computed , Ultrasonography
8.
J Am Coll Radiol ; 14(5S): S293-S306, 2017 May.
Article in English | MEDLINE | ID: mdl-28473086

ABSTRACT

Stress fractures, including both fatigue and insufficiency types, are frequently encountered in clinical practice as a source of pain in both athletes and patients with predisposing conditions. Radiography is the imaging modality of choice for baseline diagnosis. MRI has greatly improved our ability to diagnose radiographically occult stress fractures. Tc-99m bone scan and CT may also be useful as diagnostic tools. Although fatigue and insufficiency fractures can be self-limited and go onto healing even without diagnosis, there is usually value in initiating prompt therapeutic measures as incomplete stress fractures have the potential of progressing to completion and requiring more invasive treatment or delay in return to activity. This is particularly important in the setting of stress fractures of the femoral neck. Accuracy in the identification of these injuries is also relevant because the differential diagnosis includes entities that would otherwise be treated significantly different (ie, osteoid osteoma, osteomyelitis, and metastasis). The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer-reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.


Subject(s)
Fractures, Stress/diagnostic imaging , Sacrum/injuries , Fractures, Bone , Humans , Magnetic Resonance Imaging , Radiology , Radiopharmaceuticals , Sacrum/diagnostic imaging , Societies, Medical , Technetium , Tomography, X-Ray Computed/methods , Ultrasonography , United States
9.
J Am Coll Radiol ; 14(5S): S81-S89, 2017 May.
Article in English | MEDLINE | ID: mdl-28473097

ABSTRACT

Evaluation for suspected inflammatory arthritis as a cause for chronic extremity joint pain often relies on imaging. This review first discusses the characteristic osseous and soft tissue abnormalities seen with inflammatory arthritis and how they may be imaged. It is essential that imaging results are interpreted in the context of clinical and serologic results to add specificity as there is significant overlap of imaging findings among the various types of arthritis. This review provides recommendations for imaging evaluation of specific types of inflammatory arthritis, including rheumatoid arthritis, seronegative spondyloarthropathy, gout, calcium pyrophosphate dihydrate disease (or pseudogout), and erosive osteoarthritis. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer-reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.


Subject(s)
Arthralgia/diagnostic imaging , Arthritis/diagnostic imaging , Chronic Pain/diagnostic imaging , Extremities/diagnostic imaging , Arthralgia/etiology , Arthritis/complications , Chronic Pain/etiology , Humans , Radiology , Societies, Medical , United States
10.
J Am Coll Radiol ; 14(5S): S90-S102, 2017 May.
Article in English | MEDLINE | ID: mdl-28473098

ABSTRACT

Chronic hip pain is a common clinical problem whose cause is often elucidated by imaging. The ACR Appropriateness Criteria for chronic hip pain define best practices of image ordering. Clinical scenarios are followed by the imaging choices and their appropriateness. The information is in ordered tables with an accompanying narrative explanation to guide physicians to order the right test. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer-reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.


Subject(s)
Arthralgia/diagnostic imaging , Chronic Pain/diagnostic imaging , Hip Joint/diagnostic imaging , Arthralgia/etiology , Chronic Pain/etiology , Diagnostic Imaging/methods , Humans , Radiology , Societies, Medical , United States
11.
J Am Coll Radiol ; 13(11): 1324-1336, 2016 Nov.
Article in English | MEDLINE | ID: mdl-27814833

ABSTRACT

There has been a rapid increase in the number of shoulder arthroplasties, including partial or complete humeral head resurfacing, hemiarthroplasty, total shoulder arthroplasty, and reverse total shoulder arthroplasty, performed in the United States over the past two decades. Imaging can play an important role in diagnosing the complications that can occur in the setting of these shoulder arthroplasties. This review is divided into two parts. The first part provides a general discussion of various imaging modalities, comprising radiography, CT, MRI, ultrasound, and nuclear medicine, and their role in providing useful, treatment-guiding information. The second part focuses on the most appropriate imaging algorithms for shoulder arthroplasty complications such as aseptic loosening, infection, fracture, rotator cuff tendon tear, and nerve injury. The evidence-based ACR Appropriateness Criteria guidelines offered in this report were reached via an extensive analysis of current medical literature from peer-reviewed journals and the application of well-established methodologies (the RAND/UCLA Appropriateness Method and the Grading of Recommendations Assessment, Development, and Evaluation) for rating the appropriateness of imaging and treatment procedures for specific clinical scenarios. Further analysis and review of the guidelines were performed by a multidisciplinary expert panel. In those instances in which there was insufficient or equivocal data for recommending the appropriate imaging algorithm, expert opinion may have supplemented the available evidence.


Subject(s)
Arthroplasty, Replacement, Shoulder , Diagnostic Imaging , Postoperative Complications/diagnostic imaging , Algorithms , Humans , United States
12.
J Am Coll Radiol ; 13(2): 147-55, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26846390

ABSTRACT

Osteonecrosis of the hip (Legg-Calvé-Perthes) is a common disease, with 10,000-20,000 symptomatic cases annually in the United States. The disorder affects both adults and children and is most frequently associated with trauma and corticosteroid usage. The initial imaging evaluation of suspected hip osteonecrosis is done using radiography. MRI is the most sensitive and specific imaging modality for diagnosis of osteonecrosis of the hip. The clinical significance of hip osteonecrosis is dependent on its potential for articular collapse. The likelihood of articular collapse is significantly increased with involvement of greater than 30%-50% of the femoral head area, which is optimally evaluated by MRI, often in the sagittal plane. Contrast-enhanced MRI may be needed to detect early osteonecrosis of the hip in pediatric patients, revealing hypoperfusion. In patients with a contraindication for MRI, use of either CT or bone scintigraphy with SPECT (single-photon emission CT) are alternative radiologic methods of assessment. Imaging helps guide treatment, which may include core decompression, osteotomy, and ultimately, need for joint replacement. The ACR Appropriateness Criteria(®) are evidence-based guidelines for specific clinical conditions that are reviewed every three years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances in which evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment.


Subject(s)
Diagnostic Imaging , Legg-Calve-Perthes Disease/diagnostic imaging , Adult , Child , Humans , Legg-Calve-Perthes Disease/pathology
13.
Skeletal Radiol ; 45(3): 357-65, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26659451

ABSTRACT

OBJECTIVE: To evaluate the position of the peroneus longus (PL) tendon relative to the cuboid tuberosity and cuboid tunnel during ankle dorsiflexion and plantarflexion using ultrasound and MRI. MATERIALS AND METHODS: The study population included two groups: 20 feet of 10 asymptomatic volunteers who underwent prospective dynamic ultrasound and 55 ankles found through retrospective review of routine ankle MRI examinations. The location of the PL tendon at the cuboid tuberosity and cuboid tunnel was designated as completely within the tunnel, indeterminate, or subluxed with respect to ankle dorsiflexion and plantarflexion. RESULTS: On dynamic ultrasound, the PL tendon was perched plantar to the cuboid tuberosity in dorsiflexion, and glided to enter the cuboid tunnel distal to the tuberosity in plantarflexion in all 20 feet. On the MRI evaluation, there was a statistically significant difference (p = 0.0006) in the location of the PL tendon between the ankles scanned in dorsiflexion and plantarflexion. CONCLUSION: Based on our findings on ultrasound and MRI, the PL tendon can glide in and out of the cuboid tunnel along the cuboid tuberosity depending on ankle position. Thus, "subluxation" of the tendon as it curves to enter the cuboid tunnel, which to the best of our knowledge has not yet been described, should be recognized as a normal, position-dependent phenomenon and not be reported as pathology.


Subject(s)
Magnetic Resonance Imaging/methods , Tarsal Bones/diagnostic imaging , Tendinopathy/diagnostic imaging , Tendon Injuries/diagnostic imaging , Tendons/diagnostic imaging , Ultrasonography/methods , Adolescent , Adult , Aged , Child , Diagnosis, Differential , Female , Humans , Male , Middle Aged , Reproducibility of Results , Sensitivity and Specificity , Young Adult
14.
Radiographics ; 35(4): 1108-22, 2015.
Article in English | MEDLINE | ID: mdl-26172355

ABSTRACT

A growing number of magnetic resonance (MR) imaging studies of the shoulder are being performed as a result of greater and earlier participation of children and adolescents in competitive sports such as softball and baseball. However, scant information is available regarding the MR imaging features of the normal sequential development of the shoulder. The authors discuss the radiographic and MR imaging appearances of the normal musculoskeletal maturation patterns of the shoulder, with emphasis on (a) development of secondary ossification centers of the glenoid (including the subcoracoid and peripheral glenoid ossification centers); (b) development of preossification and secondary ossification centers of the humeral head and the variable appearance and number of the secondary ossification centers of the distal acromion, with emphasis on the formation of the os acromiale; (c) development of the growth plates, glenoid bone plates, glenoid bare area, and proximal humeral metaphyseal stripe; and (d) marrow signal alterations in the distal humerus, acromion, and clavicle. In addition, the authors discuss various imaging interpretation pitfalls inherent to the normal skeletal maturation of the shoulder, examining clues that may help distinguish normal development from true disease (eg, osteochondral lesions, labral tears, abscesses, fractures, infection, tendon disease, acromioclavicular widening, and os acromiale). Familiarity with the timing, location, and appearance of maturation patterns in the pediatric shoulder is crucial for correct image interpretation.


Subject(s)
Acromioclavicular Joint/anatomy & histology , Acromioclavicular Joint/growth & development , Humerus/anatomy & histology , Humerus/growth & development , Scapula/anatomy & histology , Scapula/growth & development , Adolescent , Child , Child, Preschool , Diagnostic Errors/prevention & control , Female , Humans , Infant , Infant, Newborn , Magnetic Resonance Imaging/methods , Male , Pediatrics/methods , Reproducibility of Results , Sensitivity and Specificity , Tomography, X-Ray Computed/methods
16.
Skeletal Radiol ; 43(4): 419-21, 2014 Apr.
Article in English | MEDLINE | ID: mdl-24449399

ABSTRACT

From June 28th to 29th, 2013, the Argentinian ISS Outreach Program took place in collaboration with the Centro de Diagnóstico Dr. Enrique Rossi in the city of Buenos Aires. A total of 690 participants attended. In the following report, we analyze the actual radiologic situation in this South American country. Outreach programs in a country such as Argentina are extremely valuable, as they provide a great opportunity for physicians that cannot travel overseas an attend international meetings such as RSNA, International Skeletal Society, or ARRS.


Subject(s)
Biomedical Research/organization & administration , Community-Institutional Relations , Internship and Residency/organization & administration , Orthopedics/organization & administration , Radiology/organization & administration , Societies, Medical/organization & administration , Argentina
17.
AJR Am J Roentgenol ; 200(5): 1077-88, 2013 May.
Article in English | MEDLINE | ID: mdl-23617493

ABSTRACT

OBJECTIVE: The purpose of this article is to review the clinical and imaging features as well as the potential complications of hip dysplasia in the young adult. Hip dysplasia is an important cause of secondary osteoarthrosis, which accounts for a significant proportion of patients requiring total hip arthroplasty. The radiographic diagnosis of mild hip dysplasia in the young adult may be subtle and is primarily based on the detection of deficient coverage of the femoral head by the acetabulum. CONCLUSION: Cross-sectional imaging, including CT and MRI, afford improved detection and characterization by providing morphologic information about acetabular deficiency. MRI also allows evaluation of potential associated injuries to the articular cartilage, the labrum, and the ligamentum teres. Familiarity with the radiographic and cross-sectional imaging findings of mild hip dysplasia in the young adult may allow a timely diagnosis and implementation of treatment strategies, which may prevent or delay the development of early osteoarthritis.


Subject(s)
Hip Dislocation, Congenital/diagnosis , Hip Joint/diagnostic imaging , Hip Joint/pathology , Image Enhancement/methods , Magnetic Resonance Imaging/methods , Tomography, X-Ray Computed/methods , Adult , Female , Humans , Male , Young Adult
18.
Endocr Pract ; 19(3): 456-61, 2013.
Article in English | MEDLINE | ID: mdl-23337139

ABSTRACT

OBJECTIVE: To elucidate the effects of prolonged bisphosphonate (BP) exposure on the development of atypical fragility fractures, and to define the associated risk factors. METHODS: Approval was obtained from the institutional review board, and a retrospective chart analysis was performed on 51 patients who had been on BPs for at least 3 years and had complete subtrochanteric or diaphyseal femoral fracture(s) between January 2005 and April 2011. All relevant data were available for 25 patients (mean age, 67.52 years). All fractures included in the study were low- or no-energy. Relevant clinical and demographic data were collected regarding age, gender, ethnicity, height, weight, and comorbid medical conditions. Imaging and laboratory data collected on all patients included: calcium, alkaline phosphatase, 25-hydroxyvitamin D (25-OHD), intact parathyroid hormone, serum c-telopeptide, and urine n-telopeptide levels, bone mineral density, radiography, and magnetic resonance imaging. RESULTS: Most of the patients in this study were Caucasian, were on alendronate, had bilateral findings, and almost half had prodromal symptoms. The 25-OHD level was suboptimal (<30 ng/mL) in 45.8% of the patients. Mean BP duration was 9.84 years, and mean bone density was in the osteopenic, not osteoporotic, range. CONCLUSION: Characteristics of patients with atypical BP-related fracture include relatively young age, long duration of BP use, suboptimal 25-OHD level, and bone density in the nonosteoporotic range. All of these may be significant risk factors for insufficiency fracture development.


Subject(s)
Diphosphonates/adverse effects , Femoral Fractures/chemically induced , Aged , Bone Density Conservation Agents/adverse effects , Bone Density Conservation Agents/therapeutic use , Diphosphonates/therapeutic use , Female , Femoral Fractures/blood , Humans , Male , Middle Aged , Retrospective Studies , Vitamin D/analogs & derivatives , Vitamin D/blood
19.
J Orthop Trauma ; 27(6): 331-5, 2013 Jun.
Article in English | MEDLINE | ID: mdl-22986315

ABSTRACT

OBJECTIVE: To describe the outcomes for patients treated at a single institution, who sustained incomplete bisphosphonate-induced femoral fractures. DESIGN: Retrospective review. SETTING: University-based academic medical center. PATIENTS: Thirty-one patients with 43 incomplete fractures met the inclusion criteria. INTERVENTION: Nonoperative management or surgical intervention for fractures with refractory symptoms or progression of fracture lucency on radiographs. MAIN OUTCOME MEASUREMENTS: Radiographic assessments and the Short Musculoskeletal Functional Assessment to gauge functional status. RESULTS: The cohort was all women with an average age of 69.2 (range: 46-92) years and had been treated with bisphosphonate therapy for an average of 9.1 (range: 5-20) years. The average healing time for all incomplete fractures was 9.4 (range: 1.5-36) months. Forty-nine percent of the fractures (21 of 43 fractures) were ultimately treated with surgery for impending complete fracture or failure of nonsurgical management. Of the incomplete fractures treated with surgery, 81% became pain free and 100% were radiographically healed at a mean of 7.1 (range: 1.5-12) months. In contrast, of the nonoperatively treated incomplete fractures, only 64% were pain free at latest follow-up, with only 18% of fractures demonstrating radiographic evidence of healing at an average of 11 (range: 6-24) months. Standardized dysfunction index from the Short Musculoskeletal Functional Assessment was better (19.7) in the surgical group than in the nonsurgical group (19.7 vs. 25.7, P = 0.0017). CONCLUSIONS: A higher percentage of patients treated surgically became asymptomatic and demonstrated radiographic evidence of healing earlier than those treated nonsurgically. Surgical intervention is effective for relief of symptoms when treating incomplete bisphosphonate-related femur fractures, and patients should be counseled to the potential benefits of prophylactic surgery. LEVEL OF EVIDENCE: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Diphosphonates/therapeutic use , Drug-Related Side Effects and Adverse Reactions/epidemiology , Femoral Fractures/epidemiology , Femoral Fractures/surgery , Fracture Fixation, Internal/statistics & numerical data , Postoperative Complications/epidemiology , Recovery of Function , Aged , Bone Density Conservation Agents/therapeutic use , Causality , Comorbidity , Female , Femoral Fractures/diagnosis , Fracture Healing , Humans , Middle Aged , New York/epidemiology , Prevalence , Retrospective Studies , Risk Factors
20.
AJR Am J Roentgenol ; 199(4): 879-83, 2012 Oct.
Article in English | MEDLINE | ID: mdl-22997382

ABSTRACT

OBJECTIVE: The objective of our study was to investigate the association between high fovea capitis (fovea alta) and hip dysplasia in young adults. MATERIALS AND METHODS: In a retrospective study, blinded observers reviewed 82 pelvic radiographic and hip MRI studies of three groups of patients: those with developmental dysplasia of the hip (DDH) (center-edge angle, ≤20°), those with borderline DDH (center-edge angle, 21°-25°), and control patients (center-edge angle, >25°). The center-edge angle and coxa valga (femoral neck-shaft angle, >135°) were assessed on pelvic radiographs, and fovea alta was assessed on MR images (delta angle, ≤10°). The Mann-Whitney and Fisher exact tests were used to correlate fovea alta with DDH and with coxa valga, respectively. Interobserver agreement for center-edge and delta angles and the diagnostic performance of fovea alta as a marker of DDH were calculated. RESULTS: Thirty-one patients with DDH, 23 with borderline DDH, and 28 without DDH were included. Excellent interobserver agreement was found for center-edge angle (concordance correlation coefficient, 0.94) and for delta angle (concordance correlation coefficient, 0.91). Fovea alta had a significant association with DDH (p<0.001) but no association with coxa valga (p>0.57). A significant difference (p<0.001) was found between patients with DDH (3.4°) and those without DDH (21.7°) with respect to mean delta angle measurements. Fovea alta had 69.4% sensitivity, 82.1% specificity, 67.2% positive predictive value, 81.0% negative predictive value, and 75.6% overall accuracy as an indicator of DDH. CONCLUSION: Fovea alta shows promise as a strong MRI marker of DDH.


Subject(s)
Femur Head/pathology , Hip Dislocation, Congenital/diagnosis , Magnetic Resonance Imaging , Acetabulum/diagnostic imaging , Acetabulum/pathology , Adolescent , Adult , Coxa Valga/diagnosis , Coxa Valga/etiology , Dimensional Measurement Accuracy , Female , Femur Head/diagnostic imaging , Hip Dislocation, Congenital/complications , Hip Dislocation, Congenital/diagnostic imaging , Humans , Male , Observer Variation , Osteoarthritis, Hip/etiology , Pelvic Bones/diagnostic imaging , Radiography , Young Adult
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