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Monoclonal antibody successes in the clinic.
Reichert, Janice M; Rosensweig, Clark J; Faden, Laura B; Dewitz, Matthew C.
Nat Biotechnol ; 23(9): 1073-8, 2005 Sep.
Article in English | MEDLINE | ID: mdl-16151394

ABSTRACT

Most monoclonal antibodies in clinical trials are owned by small biotech companies. But with blockbuster-sized revenues and approval rates higher than those for small-molecule drugs, that all may be set to change.


Subject(s)
Antibodies, Monoclonal/therapeutic use , Immunotherapy/methods , Animals , Antibodies, Monoclonal/chemistry , Biotechnology/methods , Biotechnology/trends , Chemistry, Pharmaceutical/trends , Clinical Trials as Topic , Drug Approval , Drug Industry/trends , Humans , Hybridomas/metabolism , Neoplasms/therapy , United States , United States Food and Drug Administration
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