[Use of human anti-Pseudomonas immunoglobulins in treatment of children with burns]. / Zastosowanie ludzkiej immunoglobuliny przeciwko Pseudomonas w leczeniu oparzonych dzieci.

This studies included 15 children with burns involving 10-55% of the whole body surface, treated at the two surgical departments in Poland. All patients have been given 0.5 mL of a 15% solution of anti-Pseudomonas immunoglobulin in a deep i.m. injections for 3 consecutive days. Immunoglobulin has generally been well tolerated, except short fever attacks. Human anti-Pseudomonas immunoglobulin prepared in the institute of Haematology and Transfusion in Warsaw prevented infections with P. aeruginosa in 12 burned children. There have been no cases of bacteremia produced by P. aeruginosa in 15 treated children with burns. The obtained results indicate efficacy of such therapy in burned children.

[Studies of the possibility of preservation of leukocyte concentrates]. / Badania nad mozliwoscia przechowywania koncentratów leukocytarnych.

The authors tried to explain whether granulocytes obtained by sedimentation on dextran can be stored, under what conditions, and for how long time. For this purpose leukocyte concentrated were stored at 4-6 degrees C and 20-24 degrees C for up to 48 hours, and the count and percent proportions of leucocytes, granulocyte viability, their phagocytic index, chemotactic ability and ATP content were determined. The investigations demonstrated a progressing decrease of the biological viability of granulocytes after 24 hours, and a further decrease after 48 hours. Particularly pronounced and early changes were noted in the chemotactic activity and ATP content. A beneficial effect was noted of higher storage temperature (20-24 degrees C) on the maintenance of chemotactic activity. The other parameters were not temperature-dependent. It seems that under such conditions leucocyte concentrates should be transfused preferably immediately after their preparation.