ABSTRACT
Naegleria fowleri is a free-living amebic organism that causes acute meningoencephalitis and brain death in young people. Though this infection is limited to the central nervous system, organ donation is usually ruled out because of the infectious nature of the donor's death. Based on the realization that this organism is limited to the brain, we successfully transplanted organs from a 12-year-old male donor dying of N. fowleri infection. Kidneys, pancreas, a lung and liver were used with no evidence of posttransplant infectious complications. This unusual cause of brain death does not preclude successful organ donation.
Subject(s)
Amebiasis/complications , Meningoencephalitis/parasitology , Naegleria fowleri , Organ Transplantation , Animals , Central Nervous System Protozoal Infections/parasitology , Child , Humans , Male , Tissue DonorsABSTRACT
The need for transplantable cadaveric organs for outweighs the supply. Improvements in the relatively new field of transplantation have dramatically improved success rates. Legislation at the state and federal levels has removed many legal roadblocks to donation. The network for the recovery and distribution of organs is well-developed and effective. OPOs, whose sole responsibility is the recovery and distribution of transplantable organs, can guide the medical staff through the process with minimal disruption of hospital routine. The recognition and referral of all potential organ donors is the responsibility of all health care professionals and helps alleviate the current shortage of transplantable organs. When simple and caring techniques are used, family consent rates for donation can approach 75%. Health care professionals remain the key to closing the imposing gap between a patient's need for transplantation and those suitable for donation.
