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1.
Gen Dent ; 72(2): 65-68, 2024.
Article in English | MEDLINE | ID: mdl-38411488

ABSTRACT

Implant failures have been associated with a diversity of etiologic processes, predominately arising from bone loss (peri-implantitis) due to inadequate maintenance of oral hygiene or excess luting agents. The aim of this article is to report a novel case of the apparent failure of a dental implant to undergo osseointegration in the presence of submerged pencil graphite. Practitioners are advised to carefully evaluate the clinical and radiographic site of a proposed implant for occult foreign substances. Embedded pencil graphite in the jawbone may promote a foreign body reaction and should be considered in the list of possible contributing factors to dental implant complications.


Subject(s)
Dental Implants , Graphite , Humans , Dental Implants/adverse effects , Graphite/adverse effects , Dental Cements , Oral Hygiene , Postoperative Complications
2.
J Prosthodont ; 32(4): 281-284, 2023 Apr.
Article in English | MEDLINE | ID: mdl-36635441

ABSTRACT

Intrusion is frequently observed as a complication associated with tooth-implant-supported prostheses: the natural tooth that serves as an abutment moves apically and out of occlusion. However, intrusion of teeth proximal to implants has yet to be reported in the literature. In this manuscript, three presentations of tooth intrusion proximal to implants are reported; potential causes of the phenomenon are discussed; and a potential treatment for patients experiencing this condition is presented. Intrusion of teeth surrounded by freestanding implants is a rare phenomenon, a cause of which may be excessively tight proximal contacts that are below the height of contour of adjacent implants. Alleviating these contacts enables the intruded tooth to erupt back and should be considered a viable treatment option.


Subject(s)
Dental Implants , Mouth, Edentulous , Tooth , Humans , Dental Implants/adverse effects , Dental Care , Dental Prosthesis, Implant-Supported/adverse effects , Dental Abutments
3.
Gerodontology ; 40(3): 398-401, 2023 Sep.
Article in English | MEDLINE | ID: mdl-36465036

ABSTRACT

OBJECTIVE: This article reports a case of a longstanding, slowly enlarging intraoral spindle cell lipoma (SCL) that had become increasingly painful during mastication. BACKGROUND: The SCL represents an uncommon variant of the conventional lipoma. There is limited information regarding this lesion in the gerodontologic literature. MATERIALS AND METHODS: A 68-year-old patient underwent an excisional biopsy of a 9-mm slightly yellow papule along the buccal mucosa. RESULTS: The surgical specimen was composed of mature adipocytes with abundant spindle cell populations and was diagnosed as a SCL. CONCLUSIONS: Timely removal of the SCL may reduce the incidence of clinical and surgical complications, particularly in older adults. The management of a SCL is complete excision, and recurrence is rare. Lesions must be carefully distinguished microscopically from its malignant counterpart, the spindle cell liposarcoma.


Subject(s)
Lipoma , Mouth Mucosa , Humans , Aged , Mouth Mucosa/pathology , Diagnosis, Differential , Lipoma/diagnosis , Lipoma/surgery , Lipoma/pathology , Biopsy
4.
Biotechnol Prog ; 36(5): e3027, 2020 09.
Article in English | MEDLINE | ID: mdl-32432828

ABSTRACT

Graphene-based nanomaterials (GBNs) have attracted considerable interest nowadays due to their wide range of applications. However, very little attention has been paid to the application of nanomaterials as potential elicitors for production of valuable metabolites. Herein, aiming to earn insight into effects of nanomaterials on secondary metabolite biosynthesis by medicinal fungi, we evaluated the influence of GBNs on growth and production of ganoderic acid (GA) by Ganoderma lucidum in submerged culture. Graphene oxide (GO), reduced graphene oxide (rGO), and rGO/Fe3 O4 nanocomposite were synthesized successfully and characterized by X-ray diffraction, Fourier transform infrared spectroscopy, and scanning electron microscopy analysis. The prepared nanomaterials were added to the culture of G. lucidum at final concentrations of 50, 100, and 150 mg/L on Day 5. The results showed that the elicitation of G. lucidum with GO and rGO decreased the cell dry weight and GA production slightly, especially in higher concentrations. However, rGO/Fe3 O4 nanocomposite not negatively affected cell growth and improved GA production. G. lucidum growth rate responded to elicitation experiments differently and depended on the type of nanomaterials and their concentrations, but almost all GBNs caused an increase in GA content (mg/100 mg dry weight). Also, field emission scanning electron microscopy morphological study showed that under elicitation, mycelia were more condensed and tightly stacked together. The findings from this study may suggest that GBNs in low concentrations could be applied as elicitors to secondary metabolites production from higher fungus, but further environmental, physiological, and biological studies required.


Subject(s)
Graphite , Nanostructures , Reishi , Triterpenes/metabolism , Ferrosoferric Oxide/chemistry , Ferrosoferric Oxide/pharmacology , Graphite/chemistry , Graphite/pharmacology , Microscopy, Electron, Scanning , Reishi/drug effects , Reishi/growth & development , Reishi/metabolism
5.
Food Chem Toxicol ; 138: 111207, 2020 Apr.
Article in English | MEDLINE | ID: mdl-32074492

ABSTRACT

In this work, the essential oils (EOs) from Litchi chinensis, Clausena anisata, Heracleum sphondylium, Pimpinella anisum, Lippia alba, Crithmum maritimum and Syzygium aromaticum were tested for their contact toxicity against the poultry red mite, Dermanyssus gallinae, a deleterious ectoparasite of aviary systems. In addition, in order to give insights on their mode of action and effectiveness, the vapor phase and residual toxicity tests were also performed. Results showed that amongst all the tested EOs, that of S. aromaticum demonstrated the highest contact toxicity, with a LC50 value of 8.9 µg/mL, followed by C. maritimum and L. chinensis EOs, with LC50 values of 23.7 and 24.7 µg/mL, respectively. L. chinensis and C. anisata EOs showed higher vapor toxicity than the other EOs. L. chinensis and S. aromaticum EOs showed promising toxic effects up to 4 days post-application. Taken together, these results highlighted L. chinensis and S. aromaticum as two promising sources of biopesticides, able to cause severe contact, vapor and residual toxicity in the poultry red mites. Given the wide plant cultivation and uses in foodstuffs, cosmetics, flavour and fragrances, these EOs may be considered cheap and ready-to-use products as valid, eco-friendly alternatives to pesticides currently used in the aviary systems.


Subject(s)
Acaricides/toxicity , Mites/drug effects , Oils, Volatile/pharmacology , Poultry Diseases/prevention & control , Poultry/parasitology , Animals , Cameroon , Clausena , Distillation , Food Safety , Italy , Litchi/chemistry , Plant Extracts/pharmacology , Plant Oils/pharmacology , Syzygium/chemistry
6.
Gerodontology ; 35(3): 276-278, 2018 Sep.
Article in English | MEDLINE | ID: mdl-30465330

ABSTRACT

OBJECTIVE: This article describes an atypical herpes zoster (HZ) infection heralded by prodromic dental pain. BACKGROUND: Trigeminal HZ is associated with any of the three divisions of the trigeminal nerve, and Ramsay Hunt syndrome is a rare variant of HZ infection of the ear, often accompanied with unilateral facial nerve palsy. MATERIALS AND METHODS: An 87-year-old man sought remedy for tooth-like pain. Within a week, he developed cutaneous, intraoral and otic eruptions, hearing loss, and mild facial palsy. RESULTS: After ruling out odontogenic pain, he was diagnosed with trigeminal HZ and Ramsay Hunt syndrome. CONCLUSION: Herpes zoster infection should be included as a possible aetiologic factor with atypical presentations of odontogenic pain. Diagnosis of trigeminal HZ infection and the Ramsay Hunt syndrome may lead to timely intervention with antivirals and improved patient outcomes.


Subject(s)
Herpes Zoster Oticus/complications , Herpes Zoster Oticus/diagnosis , Herpes Zoster/complications , Herpes Zoster/diagnosis , Toothache/etiology , Trigeminal Nerve/virology , Aged, 80 and over , Antiviral Agents/therapeutic use , Herpes Zoster/drug therapy , Herpes Zoster Oticus/drug therapy , Humans , Male , Valacyclovir/therapeutic use
7.
Eng Life Sci ; 18(5): 298-307, 2018 May.
Article in English | MEDLINE | ID: mdl-32624909

ABSTRACT

Recently, bacterial cellulose (BC) based wound dressing have raised significant interests in medical fields. However, to our best knowledge, it is apparent that the BC itself has no antibacterial activity. In this study, we optimized graphene oxide-silver (GO-Ag) nanohybrid synthesis using Response Surface Methodology and impregnate it to BC and carefully investigate their antibacterial activities against both the Gram-negative bacteria Escherichia coli and the Gram-positive bacteria Staphylococcus aureus. We discover that, compared to silver nanoparticles, GO-Ag nanohybrid with an optimal GO suspension's pH and [ G O ] [ A g N O 3 ] ratio is much more effective and shows synergistically enhanced, strong antibacterial activities at rather low dose. The GO-Ag nanohybrid is more toxic to E. coli than that to S. aureus. The antibacterial and mechanical properties of BC/GO-Ag composite are further investigated.

8.
Gen Dent ; 59(6): 504-6, 2011.
Article in English | MEDLINE | ID: mdl-22313923

ABSTRACT

Injudicious use of over-the-counter 3% hydrogen peroxide, a relatively potent oxidative agent, can result in a chemical burn to the oral mucosa. This article describes a patient who rinsed with 3% hydrogen peroxide for periods of more than two minutes as a self-prescribed remedy for oral discomfort following seafood ingestion. Subsequently, the patient experienced pain and extensive chemical burns of the sublingual and buccal mucosa and gingiva. In addition, the buccal mucosa underwent necrosis. Prolonged oral mucosal contact with 3% hydrogen peroxide is ill-advised.


Subject(s)
Burns, Chemical/etiology , Hydrogen Peroxide/adverse effects , Mouth Mucosa/injuries , Mouthwashes/adverse effects , Oxidants/adverse effects , Adult , Anti-Infective Agents, Local/adverse effects , Drug Combinations , Follow-Up Studies , Gingiva/injuries , Humans , Lip/injuries , Male , Mouth Mucosa/pathology , Necrosis , Salicylates/adverse effects , Terpenes/adverse effects , Time Factors , Tongue/injuries
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