ABSTRACT
It is presented the case of a fifty years old women, diagnosed 3 years ago with systemic lupus erythematosus, under therapy with prednisone and cyclophosphamid therapy. She was admitted in our hospital for right decompensated heart disease and the presence of an apical right ventricular mass occluding part of the right ventricular cavity. The endomyocardial biopsy was made to clearify the nature of this mass. After processing the specimen, the histological study evidenciated an organizing apical thrombotic mass formed in a large right ventricular cavity in conditions of pulmonary hypertention. There are presented data concerning the adverse effects of the systemic lupus erythematosus drug therapy, as well. In these circumstances, we demonstrated histologically, that both conditions could alter the heart morphology.
Subject(s)
Adrenal Cortex Hormones/adverse effects , Endomyocardial Fibrosis/chemically induced , Lupus Erythematosus, Systemic/drug therapy , Biopsy , Endocardium/pathology , Endomyocardial Fibrosis/pathology , Female , Humans , Lupus Erythematosus, Systemic/pathology , Middle AgedABSTRACT
The authors examined 65 children with closed head trauma of varying severity and 68 children with other acute neurological diseases. A new method of the diagnosis and assessment of the severity of closed craniocerebral injury, namely, crystallographic examination of the patients' cerebrospinal fluid, was used in the study. The method helped to establish the clinical forms of closed head trauma and to determine its severity and the presence of complications.
