Lingual Malignant Peripheral Nerve Sheath Tumor in a Chinese Pug Dog.

A 9-year-old spayed/female Chinese Pug dog presented for evaluation of a mass located on the rostral aspect of the tongue. An incisional biopsy was acquired, submitted, and interpreted as a possible granular cell tumor based on hematoxylin and eosin, and periodic acid Schiff histopathologic staining characteristics. The diagnosis was supported by immunohistochemical evaluation that was positive for S-100, vimentin, and neuron-specific enolase. Based on the absence of mitotic figures in the incisional biopsy, a partial glossectomy was performed with gross margins of at least 1-cm. The excisional biopsy revealed significant features of malignancy, with neoplastic cells in close association with peripheral nerves, consistent with malignant peripheral nerve sheath tumor. Tumor-free margins were obtained, and the glossectomy had expected healing with no recurrence apparent 6-months following surgery.

Surgical removal of an abscess associated with Fusarium solani from a Kemp's ridley sea turtle (Lepidochelys kempii).

A cold-stunned Kemp's ridley sea turtle, Lepidochelys kempii, developed an abscess associated with Fusarium solani, Vibrio alginolyticus, and a Shewenalla species after receiving a bite wound to the front flipper during rehabilitation. The lesion failed to respond to medical therapy and was treated successfully with surgery. Histopathology of the excised tissue demonstrated septic heterophilic inflammation with necrosis and granulation tissue, fungal elements, and bacteria, despite appropriate antimicrobial therapy. Variably thick bands of dense collagenous tissue partially surrounded affected areas which might have limited drug penetration into the tissue. Postoperative healing and eventual releases were uneventful. This is the first report of surgical treatment of cutaneous Fusarium infection in a sea turtle and supports surgery as an effective treatment for a fungal abscess in a reptile.

Isolation and sequence-based identification of Oxyporus corticola from a dog with generalized lymphadenopathy.

The present case report describes isolation of the fungus Oxyporus corticola from multiple lymphocutaneous tissues of a Beagle dog. Until recently, this fungus had not been reported in the human or veterinary medical literature as a cause of animal disease. A single previous report also involved infection in a German Shepherd Dog, a breed with reported increased susceptibility to disseminated fungal infection and dysfunctional immune response. Isolates were non-sporulating and required molecular identification methods for prompt differentiation from other fungal pathogens. Risk factors for infection with O. corticola are unknown.