Parameter and process significance in mechanistic modeling of cellulose hydrolysis.

A process-based model relevant to landfill and anaerobic digesters was developed, which included a novel approach to biomass transfer between a cellulose-bound biofilm and biomass in the bulk liquid. Model results highlighted the significance of the bacterial colonization of cellulose particles by attachment through contact in solution. Simulations revealed that both enhanced colonization and cellulose degradation are associated with reduced cellulose particle size, increased biomass populations in solution and increased cellulose-binding ability of the biomass. This suggests that transportation of biomass into the system from elsewhere and/or bacterial inoculation of such systems could enhance degradation significantly. A sensitivity analysis of the system parameters revealed the biological rate and yield properties of the hydrolyzing bacteria are most significant with regard to cellulose degradation in the system.

Stability of the Le Fort I maxillary osteotomy after rigid internal fixation.

PURPOSE: The purpose of this study was to evaluate the postsurgical stability of the Le Fort I osteotomy with impaction in which rigid internal fixation was used for stabilization. MATERIALS AND METHODS: Lateral cephalograms of 19 patients were evaluated. Descriptive statistics were compiled that included absolute linear and angular measurements as well as absolute changes in measurements for successive cephalometric radiographs. Comparisons were made from 1) presurgery to immediate postsurgery, 2) immediate postsurgery to splint removal, 3) splint removal to longest follow-up, and 4) immediate postsurgery to longest follow-up. Repeated measures analysis of variance were used to describe significant differences for absolute changes in measurements. RESULTS: All surgical movements were significant except for horizontal position of dental structures, horizontal position of the posterior mandible, and posterior vertical facial height. All significant movement from immediate postsurgery to splint removal was secondary to removal of the occlusal splint. Changes were minimal from splint removal to longest follow-up, with only 3 of 24 measurements showing statistically significant differences. These measurements related to tooth position and were affected by postsurgical orthodontics. The data derived from this study were also compared with those found in similar studies in which fixation was by wire osteosynthesis. CONCLUSIONS: The magnitude of postoperative movement was considerably less with rigid internal fixation than that reported with the use of wire fixation. This is attributed to the increased stabilizing effect of rigid internal fixation.

Testing progressive loading of endosteal implants with the Periotest: a pilot study.

The progressive loading of implants was first suggested by Misch in 1980. A major indicator of successful osseointegration is lack of implant mobility. In a pilot study, 26 implants were placed in eight patients. Fifteen of the implants were progressively loaded before placement of the final restorations. The remaining 11 implants were allowed to heal with healing abutments only and were not loaded until placement of the final restorations. Three measurements were taken for each of the implants at the time of uncovering and at the final restoration appointment using the Periotest. The mean change in Periotest values was -0.27 for the non-loaded group as compared with -1.51 for the progressively loaded group. There was a significantly larger increase (P < 0.001) in implant rigidity for the progressively loaded group. Progressive loading appears to enhance implant rigidity. The Periotest has the potential of being a valuable instrument for the determination of osseointegration.