ABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Subarachnoid Hemorrhage/complications , Oculomotor Nerve Diseases/etiology , Diplopia/etiologyABSTRACT
Objetivos. Describir las características neurorradiológicas de una serie de astrocitomas corticales de alto grado de malignidad en su fase inicial de desarrollo y su patrón de crecimiento durante un corto período de tiempo. Material y métodos. Estudio observacional retrospectivo de los hallazgos neurorradiológicos de 6 pacientes que, tras una primera crisis epiléptica, mostraron lesiones focales corticales supratentoriales que fueron seguidas clínico-radiológicamente durante un corto período de tiempo, tras el cual se estableció el diagnóstico de astrocitoma de alto grado de malignidad, Resultados. En los estudios de resonancia magnética (RM) de todos los pacientes se constató una pequeña lesión cortical hiperintensa en secuencias T2 con realce leve o moderado con la administración de contraste (en 5 de ellos). En los 6 pacientes se llevó a cabo un seguimiento radiológico en los 6 primeros meses tras el examen inicial (media: 79 días), que reveló un marcado crecimiento de las lesiones. Tras esta segunda RM, los pacientes fueron sometidos a cirugía citorreductora, y se estableció el diagnóstico histológico de astrocitomas de alto grado (glioblastoma en 5 pacientes y oligoastrocitoma anaplásico en uno). Conclusión. Los astrocitomas de alto grado de malignidad de origen cortical supratentorial en estadios iniciales pueden presentarse en los estudios neurorradiológicos de forma atípica. La presencia de una lesión cortical con realce leve o moderado tras la administración de contraste en un paciente que ha presentado una primera crisis epiléptica debería incluir en su diagnóstico diferencial los astrocitomas de alto grado de malignidad (AU)
Objectives. To describe the neuroradiological characteristics of a series of high grade cortical astrocytomas in the initial phase of development and their pattern of growth during a short time period. Material and methods. This was a retrospective observational study of the neuroradiological findings in six patients diagnosed with high grade astrocytoma. All presented with a new onset epileptic seizure and focal supratentorial cortical lesions. The diagnosis was established after a short period of clinical and radiological follow-up. Results. Magnetic resonance imaging (MRI) detected a small cortical lesion that was hyperintense in T2-weighted sequences in all six patients. This lesion showed slight or moderate enhancement after the administration of a contrast agent in five patients. All six patients underwent follow-up MRI within six months of the initial MRI examination (mean 79 days). Follow-up MRI showed marked growth of the lesions in all cases, and the histological diagnosis of high grade astrocytoma (glioblastoma in five patients and anaplastic oligoastrocytoma in one) was established after surgical debulking. Conclusion. High grade astrocytomas originating in the supratentorial cortex can have an atypical neuroradiological presentation in the early stages. High grade astrocytoma should be included in the differential diagnosis of a cortical lesion that enhances slightly or moderately after the administration of contrast material in a patient with a new onset epileptic seizure (AU)
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Astrocytoma/pathology , Astrocytoma , Glioblastoma , Magnetic Resonance Imaging/trends , Magnetic Resonance Imaging , Early Diagnosis , Retrospective Studies , /methods , Diagnosis, Differential , Magnetic Resonance Spectroscopy/methodsABSTRACT
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Subject(s)
Humans , Male , Female , Glioma/epidemiology , Glioma/prevention & control , Magnetic Resonance Imaging/trends , Prognosis , Glioma/physiopathology , Glioma , AstrocytomaABSTRACT
OBJECTIVES: To describe the neuroradiological characteristics of a series of high grade cortical astrocytomas in the initial phase of development and their pattern of growth during a short time period. MATERIAL AND METHODS: This was a retrospective observational study of the neuroradiological findings in six patients diagnosed with high grade astrocytoma. All presented with a new onset epileptic seizure and focal supratentorial cortical lesions. The diagnosis was established after a short period of clinical and radiological follow-up. RESULTS: Magnetic resonance imaging (MRI) detected a small cortical lesion that was hyperintense in T2-weighted sequences in all six patients. This lesion showed slight or moderate enhancement after the administration of a contrast agent in five patients. All six patients underwent follow-up MRI within six months of the initial MRI examination (mean 79 days). Follow-up MRI showed marked growth of the lesions in all cases, and the histological diagnosis of high grade astrocytoma (glioblastoma in five patients and anaplastic oligoastrocytoma in one) was established after surgical debulking. CONCLUSION: High grade astrocytomas originating in the supratentorial cortex can have an atypical neuroradiological presentation in the early stages. High grade astrocytoma should be included in the differential diagnosis of a cortical lesion that enhances slightly or moderately after the administration of contrast material in a patient with a new onset epileptic seizure.
Subject(s)
Astrocytoma/diagnosis , Brain Neoplasms/diagnosis , Cerebral Cortex , Magnetic Resonance Imaging , Neuroimaging , Adult , Aged , Female , Humans , Male , Middle Aged , Neuroimaging/methods , Retrospective StudiesABSTRACT
El objetivo de esta comunicación es ilustrar los hallazgos por resonancia magnética y tomografía computarizada del sarcoma fibromixoide de bajo grado de localización intracraneal extraaxial del que solo existen tres casos descritos en la literatura médica previamente. Para ello presentamos el caso de una mujer de 18 años con una historia de hipoacusia, acúfenos, cefalea occipital y paresia facial izquierda de 5 meses de evolución. En la tomografía computarizada se objetivó una gran lesión expansiva homogénea en el ángulo pontocerebeloso izquierdo que erosionaba el peñasco y afectaba al agujero rasgado posterior; en la resonancia magnética se comportaba como una lesión homogénea e isointensa en T1 y heterogénea e hipointensa en T2 en relación con el parénquima cerebral con realce de forma intensa y homogénea con la administración de contraste. El diagnóstico definitivo se estableció con la anatomía patológica y la inmunohistoquímica (AU)
The aim of this report is to show the MRI and CT findings for an extra-axial intracranial low-grade fibromyxoid sarcoma. To our knowledge, only three similar cases have been reported to date. We present the case of an 18-year-old woman who presented with a five-month history of hypoacusia, tinnitus, occipital headache, and left facial paresis. CT showed a large, homogeneous, expansive lesion in the left pontocerebellar angle that was eroding the promontory and affecting the posterior jugular foramen. At MRI, the lesion was homogeneous and isointense with respect to the cerebral parenchyma on T1-weighted sequences and heterogeneous and hypointense on T2-weighted sequences; after the administration of contrast material, it showed intense, homogeneous enhancement. The definitive diagnosis was established by histopathologic and immunohistochemical study (AU)
Subject(s)
Humans , Female , Adult , Liposarcoma, Myxoid , Connective Tissue , Connective Tissue Diseases/pathology , Connective Tissue Diseases , Magnetic Resonance Imaging/methods , Magnetic Resonance Imaging , /methods , Immunohistochemistry/methods , Gadolinium , Cerebellar Cortex/pathology , Diagnosis, Differential , Fibrosarcoma , Cerebellar Cortex , Cerebellar NeoplasmsABSTRACT
The aim of this report is to show the MRI and CT findings for an extra-axial intracranial low-grade fibromyxoid sarcoma. To our knowledge, only three similar cases have been reported to date. We present the case of an 18-year-old woman who presented with a five-month history of hypoacusia, tinnitus, occipital headache, and left facial paresis. CT showed a large, homogeneous, expansive lesion in the left pontocerebellar angle that was eroding the promontory and affecting the posterior jugular foramen. At MRI, the lesion was homogeneous and isointense with respect to the cerebral parenchyma on T1-weighted sequences and heterogeneous and hypointense on T2-weighted sequences; after the administration of contrast material, it showed intense, homogeneous enhancement. The definitive diagnosis was established by histopathologic and immunohistochemical study.
Subject(s)
Cerebellar Neoplasms/diagnosis , Cerebellopontine Angle , Sarcoma/diagnosis , Adolescent , Female , HumansABSTRACT
OBJECTIVE: To determine whether edema can be assessed by MRI using T2-weighted signal intensity of hemispheric white matter in cirrhotic patients. METHODS: Fast-FLAIR and magnetization transfer images were obtained before (24) and after (11) liver transplantation. T2-weighted abnormalities on baseline scans and their time-course changes were analyzed and compared with MT ratios (MTR). RESULTS: Fast-FLAIR baseline images showed faint to substantial, bilateral, symmetric increased signal intensity along the hemispheric white matter in or around the corticospinal tract in 23/24 patients. After liver transplantation the signal abnormalities gradually recovered. This gradual decrease in signal intensity correlated with an increase in MTR values. CONCLUSION: Asymptomatic symmetric high-signal intensity in the hemispheric white matter on fast-FLAIR MR images is present in cirrhosis. Normalization of this finding after successful liver transplantation and its correlation with MTR values suggest that this signal abnormality reflects mild edema.
