[Depressive schizoaffective disorder (typology and manifest episodes)].

A group of patients (n=48) with a manifestation of depressive schizoaffective disorder (SAD) (F25.1 ICD-10) was studied. The considerable frequency (79.2%) of pre-manifest affective disorders, which preceded the development of psychosis in overwhelming majority of cases (81.6%), was found. In accordance with the modality of the affect, pre-manifest affective disorders were attributed to depression (60.5%), bipolar affective disorder (31.6%), with dual phases, or, more rarely, with continuous course, and hypomania (7.9%). The considerable frequency (47.9%) of hypomania, bipolar disorder, mixed depression, alternating variants of mixed disorders was found at the active stage of current depressive SAD, in the end of the attack or in the next post-psychotic period without concomitant positive symptoms. Depending on the number of psychopathological syndromes, authors singled out mono- and polymorphic structures of a manifestation of depressive SAD. A number of significant clinical features inherent to the polymorphic clinical structure of depressive SAD, including those with mixed affective disorders, was noted compared to the monomorphic structure of the attack.

[Connective tissue dysplasia: the main gastrointestinal manifestations].

Gastrointestinal tract as one of the collagen organ systems, will inevitably become involved in the pathological process in connective tissue dysplasia. In order to optimize diagnosis and treatment tactics of practitioner choice needs to know the major gastrointestinal manifestations of connective tissue dysplasia and to distinguish between concepts: visceral manifestations of connective tissue dysplasia (syndromes of digestive diseases associated with connective tissue dysplasia), maldevelopments and diseases of the digestive system associated with connective tissue dysplasia. The authors have developed and presented a classification of major gastrointestinal syndromes in connective tissue dysplasia.