Subject(s)
Carcinoma, Hepatocellular/therapy , Chemoembolization, Therapeutic/adverse effects , Liver Abscess/diagnostic imaging , Liver Neoplasms/therapy , Phlebitis/diagnostic imaging , Portal Vein/diagnostic imaging , Aged , Carcinoma, Hepatocellular/diagnostic imaging , Humans , Liver Abscess/chemically induced , Liver Neoplasms/diagnostic imaging , Male , Phlebitis/chemically induced , Tomography, X-Ray ComputedABSTRACT
We present the case of a 79-year-old male who underwent endoscopic retrograde cholangiopancreatography (ERCP) after cholangitis. The papilla was rigid and the biliary tract was dilated with sharpening of the distal bile duct, with no obvious cause. There was no bile flow after sphincterotomy, no stone after sweeping the duct with a balloon and the brush did not expand properly when trying to obtain cytologic material. Finally, a plastic stent was placed and purulent bile flowed. Biopsies of the papilla were taken due to the suspicion of tumor infiltration. The next day, the patient had pain in the right upper quadrant and blood tests highlighted mild anemization.
Subject(s)
Cholangiopancreatography, Endoscopic Retrograde , Liver Diseases , Aged , Cholangiopancreatography, Endoscopic Retrograde/adverse effects , Common Bile Duct , Gastrointestinal Hemorrhage , Hematoma/diagnostic imaging , Hematoma/etiology , Humans , Male , Sphincterotomy, EndoscopicABSTRACT
No disponible
Subject(s)
Humans , Female , Aged , Aspergillosis/diagnostic imaging , Brain Diseases/microbiology , Intestinal Diseases/microbiology , Fatal Outcome , Balloon Enteroscopy , Tomography, X-Ray Computed , Brain Diseases/diagnostic imaging , Intestinal Diseases/diagnostic imaging , Pulmonary Aspergillosis/diagnostic imagingABSTRACT
No disponible
Subject(s)
Humans , Male , Aged , Rhabdomyolysis/chemically induced , Sorafenib/adverse effects , Antineoplastic Agents/adverse effects , Sorafenib/therapeutic use , Fatal Outcome , Antineoplastic Agents/therapeutic use , Carcinoma, Hepatocellular/drug therapyABSTRACT
A 72-year-old female presented with abdominal pain and constipation and intestinal dilation was found. Abdominal computed tomography showed two areas of thickening and stenosis in the proximal jejunum and preterminal ileum, with an unknown etiology. Exploratory laparotomy was proposed but the patient suffered a sudden and progressive decrease in consciousness. Cranial computed tomography showed an ischemic area and a midline shift. Brain biopsies suggested infection by Aspergillus Fumigatus. Despite antifungal drugs, the patient had a progressive clinical deterioration and died. The autopsy concluded a systemic infection due to Aspergillus Fumigatus. Invasive aspergillosis is a serious fungal infection and usually occurs in immunocompromised patients. It mainly affects the lungs, followed by the gastrointestinal tract. The most frequent location in gastrointestinal involvement is the small bowel. Gastrointestinal involvement is more frequent in invasive disease. Although, there are case reports of isolated gastrointestinal aspergillosis, even in immunocompetent patients without risk factors. The prognosis is poor.
Subject(s)
Aspergillosis , Aged , Antifungal Agents/therapeutic use , Aspergillosis/complications , Aspergillosis/diagnostic imaging , Aspergillosis/drug therapy , Female , Humans , Immunocompromised Host , Intestine, SmallABSTRACT
We present a case of rhabdomyolysis related to treatment with sorafenib in a patient with multifocal hepatocellular carcinoma. Rhabdomyolysis is a severe situation and potentially fatal. There are no laboratory data that can predict this condition. Early diagnosis is essential for prognosis. Rhabdomyolysis has been described as an adverse reaction of several drugs but it is not frequently related to sorafenib.
Subject(s)
Carcinoma, Hepatocellular , Liver Neoplasms , Rhabdomyolysis , Carcinoma, Hepatocellular/drug therapy , Humans , Liver Neoplasms/drug therapy , Prognosis , Rhabdomyolysis/chemically induced , Sorafenib/adverse effectsABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Esophageal Diseases/pathology , Esophagus/pathology , Necrosis , Parenteral Nutrition/methods , Omeprazole/administration & dosage , Hematemesis/complications , Gastroscopy/methods , Esophageal Mucosa/diagnostic imaging , Esophageal Diseases/diet therapy , Esophagitis/physiopathologyABSTRACT
No disponible
Subject(s)
Humans , Female , Adolescent , Hypertension, Portal/etiology , Klippel-Trenaunay-Weber Syndrome/complications , Portal Vein/abnormalities , Esophageal and Gastric Varices/diagnostic imagingABSTRACT
Female of 17 years-old with Klippel-Trenaunay syndrome: port-wine stain, overgrowth of bone and soft tissue in limbs, dental malposition and intellectual disability. Moreover, severe portal hypertension due to portal vein malformation. The Klippel-Trenaunay syndrome includes venous and capillary malformations in the skin, hypertrophy of bones and soft tissue in a limb and, in some patients, lymphatic malformations. Structural abnormalities of the deep venous system can also occur in addition to the key clinical features, although there are few case reports with portal hypertension due to portal vein malformation published.
Subject(s)
Hypertension, Portal/etiology , Klippel-Trenaunay-Weber Syndrome/complications , Portal Vein/abnormalities , Adolescent , Female , Humans , Hypertension, Portal/diagnostic imagingSubject(s)
Esophagitis/diagnostic imaging , Esophagoscopy , Gastrointestinal Hemorrhage/diagnostic imaging , Alcoholism/complications , Colonic Pseudo-Obstruction/complications , Esophagitis/complications , Esophagitis/therapy , Food, Formulated , Gastrointestinal Hemorrhage/etiology , Gastrointestinal Hemorrhage/therapy , Humans , Male , Middle Aged , Necrosis , Omeprazole/therapeutic use , Parenteral Nutrition , Sepsis/complications , Smoking/adverse effects , Urinary Tract Infections/complicationsABSTRACT
No disponible
Subject(s)
Humans , Female , Middle Aged , Pemphigoid, Benign Mucous Membrane/diagnostic imaging , Deglutition Disorders/etiology , Esophagitis/diagnostic imaging , Pemphigoid, Benign Mucous Membrane/complications , Diagnosis, Differential , Gastroscopy/methods , Prednisone/administration & dosage , Clobetasol/administration & dosage , Lidocaine/administration & dosage , Endoscopy, Digestive System/methods , Esophagitis/drug therapyABSTRACT
No disponible
Subject(s)
Humans , Female , Aged , Adrenal Cortex Hormones/adverse effects , Aspergillosis/diagnosis , Polymerase Chain Reaction , Adrenal Cortex Hormones/therapeutic use , Celiac Disease/complications , Immunocompetence , Intracranial Hemorrhages/complications , Intracranial Hemorrhages/diagnostic imaging , Lung Diseases, Fungal/diagnosis , Macrophages/drug effects , Aspergillosis/microbiology , Brain Edema/diagnostic imaging , Brain Edema/etiologySubject(s)
Esophageal Diseases/pathology , Pemphigoid, Benign Mucous Membrane/pathology , Anti-Inflammatory Agents/therapeutic use , Deglutition Disorders/etiology , Esophageal Diseases/complications , Esophageal Diseases/drug therapy , Female , Gastroscopy , Humans , Immunosuppressive Agents/therapeutic use , Middle Aged , Pemphigoid, Benign Mucous Membrane/complications , Pemphigoid, Benign Mucous Membrane/drug therapy , Stomatitis, Aphthous/complications , Ulcer/etiologyABSTRACT
La sarcoidosis es una enfermedad granulomatosa sistémica de etiología incierta, caracterizada por la formación de granulomas no necrotizantes. La afectación más frecuente es la pulmonar y mediastínica, aunque puede afectar a cualquier órgano. La afectación hepática ocurre en el 50-65% de los casos, pero suele ser subclínica o descubierta en el estudio de una alteración de las enzimas hepáticas. El debut de una sarcoidosis como una tumoración hepática aislada en muy inusual. La biopsia hepática suele ser necesaria para confirmar el diagnóstico y el diagnóstico diferencial debe establecerse con cualquier enfermedad hepática granulomatosa de carácter infeccioso o autoinmune y la exclusión de malignidad. Presentamos un caso clínico de una paciente diagnosticada de sarcoidosis hepática aislada simulando una lesión única hepática metastásica. La biopsia hepática fue diagnóstica
Sarcoidosis is a systemic granulomatous disease with an uncertain etiology, characterized by the production of non-necrotizing granulomas. The most frequent presentation is pulmonary and mediastinal, although it might affect any other organ. Hepatic alterations occur in 50 to 65% of the cases. Nevertheless, it is commonly subclinical or detected during a study of the alteration of liver enzymes. It is very unusual that disease onset occurs as an isolated hepatic tumor. A hepatic biopsy is usually required to confirm the diagnosis. A differential diagnosis must be established via any hepatic granulomatous disease, infectious or autoimmune disease as well as the exclusion of malignancy. We present a clinical case of a female diagnosed with an isolated hepatic sarcoidosis that simulated a unique hepatic metastatic lesion. The hepatic biopsy was diagnostic
Subject(s)
Humans , Female , Aged , Sarcoidosis/complications , Hepatitis/complications , Granuloma/diagnosis , Neoplasm Metastasis/diagnosis , Diagnosis, Differential , Incidental FindingsABSTRACT
Sarcoidosis is a systemic granulomatous disease with an uncertain etiology, characterized by the production of non-necrotizing granulomas. The most frequent presentation is pulmonary and mediastinal, although it might affect any other organ. Hepatic alterations occur in 50 to 65% of the cases. Nevertheless, it is commonly subclinical or detected during a study of the alteration of liver enzymes. It is very unusual that disease onset occurs as an isolated hepatic tumor. A hepatic biopsy is usually required to confirm the diagnosis. A differential diagnosis must be established via any hepatic granulomatous disease, infectious or autoimmune disease as well as the exclusion of malignancy. We present a clinical case of a female diagnosed with an isolated hepatic sarcoidosis that simulated a unique hepatic metastatic lesion. The hepatic biopsy was diagnostic.
Subject(s)
Liver Diseases/diagnosis , Liver Neoplasms/diagnosis , Liver Neoplasms/secondary , Sarcoidosis/diagnosis , Aged , Biopsy , Diagnosis, Differential , Female , Granuloma/diagnosis , Humans , Liver Diseases/diagnostic imaging , Liver Diseases/therapy , Liver Neoplasms/diagnostic imaging , Magnetic Resonance Imaging , Positron Emission Tomography Computed Tomography , Sarcoidosis/diagnostic imaging , Sarcoidosis/therapyABSTRACT
No disponible
Subject(s)
Humans , Male , Aged , Choledochal Cyst/diagnostic imaging , Cholangitis/etiology , Connective Tissue/pathologyABSTRACT
Peribiliary cysts involve cystic dilation of the extramural peribiliary glands in the liver hilum and portal tracts. Most peribiliary cysts are asymptomatic. We present the case of a patient without any prior liver disease who developed obstructive jaundice and a liver abscess due to peribiliary cysts. Peribiliary cysts usually appear in patients with severe chronic liver disease and are asymptomatic, although they sometimes appear in patients without prior liver disease and cause serious complications.