Sensitisation to Pollen Allergens in Children and Adolescents of Different Ancestry Born and Living in the Same Area.

Background: Allergy can start at early ages, with genetic and environmental factors contributing to its development. Aim: The study aimed to describe the pattern of sensitisation and allergy in children and adolescents of Spanish versus Moroccan ancestry but born in the same rural area of Spain. Methods: Participants were children and adolescents (3-19 years) of Spanish or Moroccan descent, born in Blanca, Murcia (Spain). A detailed questionnaire was completed, and skin prick tests were performed to assess reactions to the most prevalent pollen allergens (O. europaea, P. pratense, S. kali, C. arizonica, P. acerifolia, A. vulgaris and P. judaica) plus molecular components Ole e 1 and Ole e 7. The association with ancestry was verified by studying participants' parents. Results: The study included 693 participants: 48% were aged 3-9 years and 52%, 10-19 years; 80% were of Spanish descent and 20% of Moroccan descent. Sensitisation to Olea europaea, Phleum pratense, Salsola kali and Cupressus arizonica were slightly higher in the Spanish group. The only significant differences were observed in sensitisation to Ole e 1 (p=0.02). Rhinitis, conjunctivitis, and rhinitis plus asthma were significantly higher in the Spanish group (p=0.03, p=0.02, p=0.007, respectively). The sensitisation pattern differed between Spanish and Moroccan parents, and between Moroccan parents and their children, but not between Spanish parents and their children. Conclusion: Both environment and ancestry may influence sensitisation and symptoms. Although the environment seems to have a stronger influence, other factors may contribute to the differences in prevalence and in the clinical entities in people of Spanish versus Moroccan descent.

Acetyl Salicylic Acid Challenge in Children with Hypersensitivity Reactions to Nonsteroidal Anti-Inflammatory Drugs Differentiates Between Cross-Intolerant and Selective Responders.

BACKGROUND: Hypersensitivity reactions to nonsteroidal anti-inflammatory drugs (NSAIDs) in children are becoming a great concern. Most studies have focused on adults, with noted discrepancies observed in the classification of hypersensitivity reactions to NSAIDs in children when compared with adults. OBJECTIVE: To phenotype a group of children with hypersensitivity reactions to NSAIDs, including paracetamol, and analyze the degree of agreement with the entities reported in adults and how they fit the proposed classifications. METHODS: The study comprised 116 children aged 0.5 to 14 years, with a clinical history indicative of hypersensitivity reactions to NSAIDs. They all underwent a single-blind oral provocation test with acetyl salicylic acid, except in those cases when this was the suspected drug, in which case the challenge was done first with ibuprofen. If positive, cross-intolerance was established and if negative, an oral provocation test with the culprit drug was performed to establish a selective response or exclude allergy. RESULTS: Of the 26% diagnosed as hypersensitive to NSAIDs, 83% were cross-intolerant and 17% selective reactors. The highest significant differences between reactors and nonreactors were observed in the time to reaction after drug intake and the clinical entity (P < .0001), followed by drug involved and age (P < .01). CONCLUSIONS: From the total number of cases confirmed with NSAID hypersensitivity, 83% were cross-intolerant. In cross-intolerant reactions, both cutaneous and respiratory manifestations are common. Acetyl salicylic acid challenge as the first approach proved to be safe and useful to establish the diagnosis.

Incidental tricuspid valve fibroelastoma associated with patent foramen ovale in a young female: Straightforward diagnosis but controversial management.

Papillary fibroelastoma is an uncommon primary cardiac tumor, predominantly associated with left-sided valvular endocardium. Affectation of tricuspid valve leaflets is rare, and management in asymptomatic patients remains controversial. We present a 30-year-old female referred for evaluation prior to bariatric surgery. A routine echocardiogram revealed a mobile cardiac mass attached to the tricuspid valve. A patent foramen ovale was also present. Tumor was surgically removed. Histology confirmed the definite diagnosis of a papillary fibroelastoma. In our case, the presence of a patent foramen ovale associated with the right-sided fibroelastoma was decisive in the decision for surgery.

Psychometric properties of the Spanish version of the Flow State Scale.

The purpose of this research was to examine the psychometric properties of a Spanish translation of the Flow State Scale (FSS; Jackson & Marsh, 1996). This instrument is used to assess the Flow State in participants of physical activity, although it can be adapted to other contexts (such as work, educational contexts, etc.). This construct can be considered the optimal psychological state to carry out an activity, being closely related to motivation and personal enjoyment (Csikszentmihalyi, 1997). A sample of 2036 athletes was recruited from diverse sports activities. The results revealed satisfactory validity and internal consistency of the instrument, obtaining a factor model made up of a main factor and nine subscales. The correlations between motivational orientations and the flow state are highlighted. The Spanish translation of this instrument is found to be acceptable, with similar psychometric properties as the original scale, although future research in other contexts is needed to support these outcomes.

Psychometric Properties of the Spanish Version of the Flow State Scale

The purpose of this research was to examine the psychometric properties of a Spanish translation of the Flow State Scale (FSS; Jackson & Marsh, 1996). This instrument is used to assess the Flow State in participants of physical activity, although it can be adapted to other contexts (such as work, educational contexts, etc.). This construct can be considered the optimal psychological state to carry out an activity, being closely related to motivation and personal enjoyment (Csikszentmihalyi, 1997). A sample of 2036 athletes was recruited from diverse sports activities. The results revealed satisfactory validity and internal consistency of the instrument, obtaining a factor model made up of a main factor and nine subscales. The correlations between motivational orientations and the flow state are highlighted. The Spanish translation of this instrument is found to be acceptable, with similar psychometric properties as the original scale, although future research in other contexts is needed to support these outcomes (AU)

El objetivo de esta investigación fue analizar las propiedades psicométricas de una versión adaptada al castellano de la Flow State Scale (FSS; Jackson y Marsh, 1996), instrumento utilizado para valorar el estado de fluidez en practicantes de actividad física, aunque adaptable a otros contextos (trabajo, educación…). Dicho constructo puede ser considerado como el estado psicológico óptimo para realizar una actividad, estando muy relacionado con la motivación y el disfrute personal (Csikszentmihalyi, 1997). Se desarrolló un estudio con 2036 participantes en diferentes actividades deportivas. Los resultados han demostrado que el instrumento posee una validez y consistencia interna aceptables, hallándose un modelo factorial compuesto por un factor principal y nueve factores secundarios. Asimismo, destacan las correlaciones entre las dos orientaciones motivacionales y el estado de fluidez. Se concluye que la adaptación al castellano del instrumento para valorar el estado de fluidez es aceptable, encontrándose propiedades psicométricas similares a las obtenidas en la escala original, aunque se necesitan nuevos trabajos en otros contextos que apoyen estos resultados (AU)