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Khirurgiia (Mosk) ; (3): 13-6, 1990 Mar.
Article in Russian | MEDLINE | ID: mdl-2141657

ABSTRACT

The results of studying ATP-ase activity of the actomyosin complex of the esophageal smooth muscles in functional cardiac obstruction (FCO) are discussed. It was established that in advancement of the diseases the ATP-ase activity of the actomyosin complex of the esophageal muscular coat diminishes steadily. Analysis of surgical treatment of 63 patients with FCO showed that in 12 patients with neglected stages of the disease (stages III and IV) its results were poor due to marked reduction of the esophageal tonus, which was linked with diminished activity of the actomyosin complex of the esophageal muscles in stages III and IV of the disease. The study provides evidence of the importance of determining ATP-ase activity of actomyosin in FCO in choice of the methods of nonoperative treatment and the time of surgical management of this pathological condition.


Subject(s)
Esophageal Achalasia/enzymology , Esophagus/enzymology , Muscle, Smooth/enzymology , Myosins/metabolism , Adult , Combined Modality Therapy , Esophageal Achalasia/therapy , Female , Humans , Male , Middle Aged , Myosins/deficiency
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