The results of the corrective rehabilitation program on the gait of amateur athletes with long-term consequences of brain injury.

OBJECTIVE: Aim: To study the results of the quality of life, the state of vestibular disorders and the nature of walking of amateur athletes with the consequences of a combat craniocerebral injury after rehabilitation treatment according to a correctional program. PATIENTS AND METHODS: Materials and Methods: The study was conducted on the basis of the Ukrainian Scientific Research Institute of Prosthetics in Kharkov. Under observation were 38 men aged 25-42 years with long-term consequences of a closed craniocerebral injury in the late long-term period. In all patients, complications after TBI were persistent headache, decreased muscle strength in the lower extremities, impaired coordination and balance, and walking patterns. All patients were involved in amateur sports before injury. The following research methods were used during the examination: visual analogue pain scale (VAS), Lovett manual muscle test, Bohannon test, ≪Timed Up and Go test≫. RESULTS: Results: All patients were randomly divided into two groups. Patients Gr.1 (n=20) were trained according to the developed program, which included training according to the PNF method, kinesiotherapy, classes on the C-mill sensory treadmill and the Hunova computer device, segmental reflex massage. Patients Gr. 2 (n=18) underwent a course of physical rehabilitation according to the generally accepted methodology of the Ministry of Health of Ukraine. After working with patients according to the developed correction and rehabilitation program, the following dynamics were observed: the quality of life on the VAS scale in Gr.1 patients had a statistically significant difference (p<0.05) compared to the primary indicator. The dynamics of the Lovett manual muscle test indicated an increase in the muscle strength of the extensor and flexor muscle groups of the lower extremities, the dynamics of the balance indicator in the standing position behind Bohann in all Gr.1 patients and acquired statistical significance (p<0,05). According to the test "Timed Up and Go" patients Gr.1 approached the standard value (p<0,05). In all patients of Gr. 2, the studied characteristics had a positive trend (p>0,05). CONCLUSION: Conclusions: Individual selection of physical exercises, development of correctional and rehabilitation programs, multidisciplinary approach has a positive impact on changes in the functional state of amateur athletes, quality of life and contributes to the return to an active social life.

IMPLEMENTATION OF THE POLISH-UKRAINIAN PROJECT "SELF-DIAGNOSIS OF BREAST CANCER IN YOUNG UKRAINIAN WOMEN" WITHIN THE FRAMEWORK OF THE RITA PROGRAM - CHANGES IN THE REGION AT THE KHARKIV STATE ACADEMY OF PHYSICAL CULTURE.

OBJECTIVE: The aim: To prove the effectiveness and necessity of implementation of the Polish-Ukrainian project"Self-diagnosis of breast cancer in young Ukrainian women within the framework of the RITA program-changes in the region(on the example of the Kharkiv State Academy of PhysicalCulture). PATIENTS AND METHODS: Materials and methods: 200 people took part in the study: 100 students and 100 lecturers and employees of the Kharkov State Academy of Physical Culture, attended lectures on epidemiology and prevention, risk factors and clinical features of breast cancer; took part in practical exercises on visual methods of breast cancer screening and the formation of self-examination skills. Each participant in the project was tested at the beginning and at the end of training, the tests included 20 questions about risk factors and clinical signs of breast cancer and an algorithm for its self-examination. Each question to which the correct answer was given was scored 1 point (the maximum number of points for one test was 20 points). RESULTS: Results: During the testing, it was found that the awareness of applicants and employees of the Kharkiv State Academy of Physical Culture regarding risk factors and clinical features of breast cancer, as well as the self-examination procedure, increased by 68% and 67%, respectively. CONCLUSION: Conclusions: The study confirms that the transfer of Polish experience to the project "Self-diagnosis of breast cancer in young Ukrainian women" contributes to the formation of a culture of disease prevention through self-observation and self-examination of young Ukrainian women, which can save human lives, since raising public awareness and gaining practical knowledge will certainly change the fate of many people.

EFFICACY OF RECREATIONAL PHYSICAL ACTIVITY FOR PERIMENOPAUSAL WOMEN WITH HYPERTENSION ONSET.

OBJECTIVE: The aim: To examine the effect of the developed wellness program on hemodynamic indices and psychological state of perimenopausal women. PATIENTS AND METHODS: Materials and methods: The study involved 27 women aged 39 to 47 years. Inclusion criteria: recorded perimenopause, climacteric syndrome, history of episodic increase in blood pressure up to 140/85 or 150/90 mmHg. Exclusion criteria: primary hypertension, diabetes mellitus, chronic contagious, systemic, oncology diseases, and mental illnesses. Research procedure comprised tracing of the heart rate, blood pressure registration, and pulse pressure calculation. Robinson index, the coefficient of endurance according to A. Kvas formula were calculated. The assessment of psychological state was made using the Spielberger-Khanin Inventory. RESULTS: Results: Multidisciplinary professionals gave classes upon wellness program at "Women's Health" school. The program included educational conversations, healthy walking, massage, psycho-corrective exercises. The dynamics of the studied parameters was analyzed after 12 weeks. Based on the anthropometric measures findings the tested women showed improvement of 6,76% weight loss; and their body mass index decreased by 6,77%. Initial numbers of Robinson index and the coefficient of endurance were above normal values. After working under the program statistically significant dynamics was observed (р <0,05), although there were still signs of cardiovascular disorders. There were statistically significant positive changes Spielberger-Khanin Inventory on State Anxiety (-9,09%) and Personal Anxiety Scales (-6,96%) (p <0,05). CONCLUSION: Conclusions: Early detection of risk factors and physical activity will help to bring a vast improvement to prognosis and quality of life of perimenopausal women with hypertension onset.

Associations of irs-1 polymorphism with various components of the metabolic syndrome in hypertensive patients

Introduction: The metabolic syndrome is one of the most discussed cross-disciplinary problems of modern medicine. Now there are various definitions and criteria of diagnostics of metabolic syndrome. The abdominal obesity is considered the main component of the metabolic syndrome, as a reflection of visceral obesity which degree is offered to be estimated on an indirect indicator ­ a waist circumference. Alongside with abdominal obesity, a number of classifications distinguish insulin resistance (IR) as a diagnostic criterion of metabolic syndrome. It is proved that IR is one of the pathophysiological mechanisms influencing the development and the course of arterial hypertension (AH), type 2 DM and obesity. There are two components in the development of IR: genetic (hereditary) and acquired. In spite of the fact that IR has the accurate genetic predisposition, exact genetic disorders of its appearance have not been identified yet, thus demonstrating its polygenic nature. The aim: To establish possible associations of the insulin receptor substrate-1 (IRS-1) gene polymorphism with the severity of the metabolic syndrome components in patients with arterial hypertension (AH). Material and methods: 187 patients with AH aged 45-55 years and 30 healthy individuals. Methods: anthropometry, reactive hyperemia, color Doppler mapping, biochemical blood analysis, HOMA-insulin resistance (IR), glucose tolerance test, enzyme immunoassay, molecular genetic method. Results: Among hypertensive patients, 103 had abdominal obesity, 43 - type 2 diabetes, 131 - increased blood triglycerides, 19 - decreased high density lipoproteins, 59 - prediabetes (33 - fasting hyperglycemia and 26 - impaired glucose tolerance), 126 had IR. At the same time, hypertensive patients had the following distribution of IRS-1 genotypes: Gly/Gly - 47.9%, Gly/Arg - 42.2% and Arg/Arg - 10.7%, whereas in healthy individuals the distribution of genotypes was significantly different: Gly/Gly - 86.8% (p <0.01), Gly/ Arg - 9.9% (p <0.01) and Arg/Arg - 3.3% (p <0.05). Hypertensive patients with Arg/Arg and Gly/Arg genotypes had significantly higher HOMA-IR (p <0.01), glucose, insulin and triglycerides levels (p <0.05), than in Gly/Gly genotype. At the same time, body mass index, waist circumference, blood pressure, adiponectin, HDL, interleukin-6, C-reactive protein, degree of endothelium-dependent vasodilation, as well as the frequency of occurrence of impaired glucose tolerance did not significantly differ in IRS-1 genotypes. Conclusions: In hypertensive patients, the genetic polymorphism of IRS-1 gene is associated with such components of the metabolic syndrome as hypertriglyceridemia and fasting hyperglycemia; it is not associated with proinflammatory state, endothelial dysfunction, dysglycemia, an increase in waist circumference and decrease in HDL.