1.
Genomics
; 13(3): 622-9, 1992 Jul.
Article
in English
| MEDLINE
| ID: mdl-1639389
ABSTRACT
One hundred highly informative simple sequence repeat (SSR) polymorphisms have been isolated and mapped to specific human chromosomes by somatic cell hybrid analysis. These markers include 97 (CA)n, 2 (AGAT)n, and a single (AACT)n repeat. All the SSRs have heterozygosities greater than 0.50 and can be amplified using identical PCR conditions. At least one SSR was detected on every chromosome, except for chromosomes 22 and Y. The frequency of (CA)n repeats on each chromosome was proportional to the relative chromosomal length, except for chromosome 15, on which a substantial excess of markers was identified.
Subject(s)
Polymorphism, Genetic , Repetitive Sequences, Nucleic Acid , Base Sequence , Chromosome Mapping , DNA/genetics , Genetic Markers , Heterozygote , Humans , Molecular Sequence Data , Polymerase Chain Reaction
2.
J Chromatogr
; 488(2): 456-62, 1989 Mar 24.
Article
in English
| MEDLINE
| ID: mdl-2745634