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1.
Eur J Orthop Surg Traumatol ; 32(8): 1583-1589, 2022 Dec.
Article in English | MEDLINE | ID: mdl-34623469

ABSTRACT

INTRODUCTION: The primary objective of this study was to compare the radiological and clinical results of anterograde and retrograde screwing in subtalar arthrodesis using a single compression screw. The secondary objective was to evaluate the subjective results and consolidation of this procedure. The hypotheses were that isolated screw fixation was sufficient to achieve good consolidation and that there was no difference between the two techniques with a similar rate of bone fusion. METHODS: This is a monocentric, retrospective, radio-clinical study based on 99 patients (101 feet), 58 males and 41 females, with an average age of 64 years. The main aetiology was post-traumatic osteoarthritis, which represented 51% of cases. Two groups were formed: group A (52 feet) consisting of fixed arthrodesis with ascending (retrograde) screwing and group D (49 feet) consisting of fixed arthrodesis with descending (anterograde) screwing. The two groups were statistically comparable in terms of demographic data as well as aetiologies and comorbidities. Arthrodeses which were not fused at 6 months were reassessed at one year and in the event of any radio-clinical doubt regarding consolidation, an additional CT scan was prescribed. Average post-operative follow-up was 11 ± 5 years (2-27 years). RESULTS: Ninety-two arthrodeses (93%) were fused at one year and 9 were considered to be in non-union, 5 (9.8%) in group A, and 4 (8.3%) in group D. We recorded 30 complications, 22 of which were due to a conflict with the screw head, 18 (34.5%) in group A and 4 (8.3%) in group D (p = 0.03). Conflict between the screw head and the heel led to the removal of the screw after consolidation of the arthrodesis. The clinical results were evaluated using Odom's criteria. Nine per cent of patients described their results as excellent, 29% as good, 51% as satisfactory and 11% found the result to be poor. CONCLUSION: The fusion rate for isolated compression screw arthrodesis is good, and there is no difference between anterograde and retrograde screws. However, the discomfort caused by the screw head being insufficiently embedded in the retrograde group led to a non-negligible number of additional surgeries to remove the screw.


Subject(s)
Osteoarthritis , Subtalar Joint , Male , Female , Humans , Middle Aged , Subtalar Joint/diagnostic imaging , Subtalar Joint/surgery , Retrospective Studies , Bone Screws , Arthrodesis/adverse effects , Arthrodesis/methods , Osteoarthritis/etiology , Osteoarthritis/surgery
2.
Eur J Orthop Surg Traumatol ; 32(5): 857-865, 2022 Jul.
Article in English | MEDLINE | ID: mdl-34152474

ABSTRACT

PURPOSE: The aim was to assess the consequences of quadriceps tendon (QT) harvest on knee extensor strength after anterior cruciate ligament reconstruction (ACL-R) compared to hamstring tendon (HT) autograft. Secondary objectives were to evaluate flexor strength recovery and search for correlation between strength status and functional outcome. METHODS: This a retrospective cohort of 44 patients who underwent ACL-R using either QT (25) or HT (19). Median age was 31.1 years. We assessed thigh muscle strength thanks to concentric iso kinetic evaluation (peak torque) at 60°.s-1, 180°.s-1, 240°.s-1 and eccentric at 30°.s-1, 7 months on average after surgery. Muscle strength values were compared to the uninjured leg in order to calculate a percentage of deficit as well as unilateral hamstring/quadriceps (H/Q) ratios. KOOS score was obtained at a mean follow-up of 18 months. RESULTS: Extensor strength deficit (concentric 60°.s-1) was one average 33.1% in the QT group and 28.2% in the HT group (p = 0.42). Difference of flexor strength deficit (concentric 60°.s-1) was close to be significant with 5% and 12% of deficit in the QT and HT group, respectively (p = 0.1), and statistically significant for high angular velocity (14% versus 3% at 240°.s-1, p = 0.04). H/Q ratios were comparable in both groups ranging from 0.62 to 0.78. Quadriceps muscle strength deficit was negatively correlated with the KOOS score (Pearson coefficient = -0.4; p = 0.005). CONCLUSION: QT autograft harvest does not yield significant quadriceps muscle weakness after ACL-R, which appear to be a pejorative factor for functional outcome. LEVEL OF EVIDENCE: IV, Retrospective study.


Subject(s)
Anterior Cruciate Ligament Injuries , Anterior Cruciate Ligament Reconstruction , Hamstring Tendons , Adult , Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Reconstruction/adverse effects , Autografts , Hamstring Tendons/transplantation , Humans , Muscle Strength/physiology , Quadriceps Muscle , Retrospective Studies , Tendons/surgery , Transplantation, Autologous
3.
Int Orthop ; 45(7): 1863-1869, 2021 07.
Article in English | MEDLINE | ID: mdl-33619586

ABSTRACT

PURPOSE: The aims of this study were (1) to collect prospectively all tibial plateau fractures admitted to our department, over two ski seasons, and to classify them according to the Schatzker and AO classifications; (2) to assess if these classifications are accurate enough to include all types of fractures; and (3) to compare theses fractures with the series found in the literature, which included very few or no skiing accidents. METHODS: During the 2016-2017 and 2017-2018 ski seasons, we prospectively included 116 tibial plateau fractures caused by downhill skiing accidents. All patients underwent standard X-rays and 2D and 3D CT scans. The fractures were classified according to the AO and Schatzker revisited classifications. RESULTS: The full series consisted of 56 males (48%) and 60 females (52%), aged 49 ± 16 years (18-77). There were 60 type B (52%) and 56 type C fractures (48%) for AO classification and 45.5% types I, II and III and 54.5% types IV, V and VI for Schatzker classification. Thirty-five frontal fractures (30%) were not differentiated under the AO classification and, likewise, associated tibial spine fractures (28.5%) were not differentiated in the Schatzker classification. We were also unable to classify anterior tibial tuberosity fractures (14.5%) and fibula head fractures (8%). The anatomo-pathological types were not so different from road traffic accidents. CONCLUSION: Contrary to our hypothesis, the anatomical-pathological damage in tibial plateau fractures resulting from downhill skiing accidents was barely any different from those found in road traffic accidents. However, despite progress in classifications with the emergence of 3D CT scans, it is still not always possible to categorise all fractures within a given classification.


Subject(s)
Tibial Fractures , Female , Hospitalization , Humans , Knee Joint , Male , Radiography , Tibia , Tibial Fractures/diagnostic imaging , Tibial Fractures/epidemiology
4.
Int Orthop ; 44(1): 179-185, 2020 01.
Article in English | MEDLINE | ID: mdl-31673741

ABSTRACT

PURPOSE: The aim of this study was to compare clinical and laximetric results in chronic, isolated posterior cruciate ligament (PCL) rupture repairs, using either a hamstring graft or an artificial ligament (ligament advanced reinforcement system (LARS®)). METHODS: Sixteen patients presenting with an isolated unilateral PCL rupture were included in this retrospective study. Initially, eight underwent a PCL reconstruction using a hamstring tendon autograft (hamstring group), and over a later period, eight further patients underwent a reconstruction using an artificial ligament with a new procedure. RESULTS: Fifteen patients were male and one female, with an average age of 29.3 years. All patients were operated on within an average time of 18 months post-injury. Pre-operative posterior laxity was equivalent (p = 0.309), 18.25 mm on average for the hamstring group and 18.75 mm for the LARS group. With an average follow-up of 24 months, residual posterior laxity was significantly improved, decreasing from 18.25 to 7.37 mm for the hamstring group (p < 0.05) with a median at 7.5 mm and from 18.75 to 5.25 mm for the LARS group (p < 0.05) with a median at 5 mm. The improvement in laxity for the hamstring group was 60% and 71.5% for the LARS group. The LARS group compares favourably (p = 0.003 and 0.01). Tegner activity level improved significantly following ligamentoplasty, with no difference between the two groups (p = 0.4). Likewise, there was no significant difference in the Lysholm and IKDC scores between the two groups (p = 0.4). CONCLUSION: The initial hypothesis of this study was proven correct. Nevertheless, a longer term study is necessary to assess the consequences of residual laxity in hamstring grafts and the long-term behaviour and tolerance of the LARS artificial ligament.


Subject(s)
Hamstring Tendons/transplantation , Joint Instability/surgery , Knee Injuries/surgery , Ligaments/transplantation , Posterior Cruciate Ligament Reconstruction/methods , Posterior Cruciate Ligament/surgery , Adolescent , Adult , Chronic Disease , Female , Follow-Up Studies , Humans , Joint Instability/etiology , Male , Middle Aged , Posterior Cruciate Ligament/injuries , Prostheses and Implants , Retrospective Studies , Transplantation, Autologous , Young Adult
5.
Eur J Orthop Surg Traumatol ; 29(6): 1271-1276, 2019 Aug.
Article in English | MEDLINE | ID: mdl-30903377

ABSTRACT

INTRODUCTION: The aim of this study was to assess the differential laxity after reconstruction of the anterior cruciate ligament (ACL) by the TLS® technique using a single tendon, the semitendinosus in four-strand graft, compared with the hamstring technique which uses both the gracilis and semitendinosus. We hypothesised that this surgical technique would provide post-surgical differential laxity measurements at least as good as those of the hamstring technique. MATERIALS AND METHODS: We carried out a prospective monocentric study on patients undergoing unilateral anterior cruciate ligament repair between December 2014 and June 2016. All patients were followed up for at least 12 months. The series compares 61 patients operated on using the TLS® technique by the same surgeon, with 33 patients operated on using the hamstring technique by a second surgeon. The main objective of the study was to compare the post-operative differential laxity, measured using the KT1000, between the two techniques. RESULTS: There was no significant difference in the patients' epidemiological characteristics and pre-operative scores between the two groups. Average pre-operative differential laxity was 6.5 mm ± 2.1 (min 3; max 12) in the TLS group and 6.4 mm ± 2.0 (min 0; max 11) in the hamstring group, with no statistically significant difference. The average post-operative difference in laxity was - 0.1 mm ± 1.9 (min - 5; max 4) in the TLS group and 0.3 mm ± 2.0 (min - 7; max 5) in the hamstring group. Again, no significant difference was observed between groups. DISCUSSION: This study demonstrates a level of post-operative differential laxity control using TLS comparable with that of the ACL reconstruction technique using a hamstring graft with preserved tibial insertion. LEVEL OF EVIDENCE: II, prospective cohort study.


Subject(s)
Anterior Cruciate Ligament Reconstruction , Bone Screws/adverse effects , Hamstring Tendons/transplantation , Joint Instability , Postoperative Complications , Tendon Transfer , Adult , Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Reconstruction/adverse effects , Anterior Cruciate Ligament Reconstruction/instrumentation , Anterior Cruciate Ligament Reconstruction/methods , Comparative Effectiveness Research , Female , Humans , Joint Instability/diagnosis , Joint Instability/etiology , Knee Joint/diagnostic imaging , Knee Joint/surgery , Magnetic Resonance Imaging/methods , Male , Middle Aged , Outcome and Process Assessment, Health Care , Postoperative Complications/diagnosis , Postoperative Complications/etiology , Tendon Transfer/adverse effects , Tendon Transfer/methods
6.
Orthop Traumatol Surg Res ; 104(4): 491-496, 2018 06.
Article in English | MEDLINE | ID: mdl-29653241

ABSTRACT

In complex fractures of the proximal tibial metaphysis and epiphysis, possible adverse outcomes after internal fixation include not only joint surface incongruity, but also lower limb malalignment requiring revision surgery. Navigation has been proven effective for the intraoperative control of lower limb alignment during osteotomy and knee arthroplasty. In complex traumatic fractures, temporary fixation by a locking screw plate allows sensor positioning followed by navigation maneuvers to adjust lower limb alignment. If malalignment is found, the construct can be modified economically by altering the diaphyseal fixation without modifying the metaphyseal screws. The objective of this study was to describe the use of navigation in three patients who required internal fixation of tibial-plateau fractures.


Subject(s)
Bone Malalignment/prevention & control , Fracture Fixation, Internal/methods , Intra-Articular Fractures/surgery , Tibial Fractures/surgery , Bone Malalignment/etiology , Bone Plates , Bone Screws , Diaphyses/surgery , Epiphyses/injuries , Epiphyses/surgery , Female , Fracture Fixation, Internal/adverse effects , Humans , Reoperation , Young Adult
8.
Orthop Traumatol Surg Res ; 103(5): 663-668, 2017 09.
Article in English | MEDLINE | ID: mdl-28629944

ABSTRACT

INTRODUCTION: Dislocation after total hip arthroplasty (THA) is a leading reason for surgical revision. The risk factors for dislocation are controversial, particularly those related to the patient and to the surgical procedure itself. The differences in opinion on the impact of these factors stem from the fact they are often evaluated using retrospective studies or in limited patient populations. This led us to carry out a prospective case-control study on a large population to determine: 1) the risk factors for dislocation after THA, 2) the features of these dislocations, and 3) the contribution of patient-related factors and surgery-related factors. HYPOTHESIS: Risk factors for dislocation related to the patient and procedure can be identified using a large case-control study. PATIENTS AND METHODS: A multicenter, prospective case-control study was performed between January 1 and December 31, 2013. Four patients with stable THAs were matched to each patient with a dislocated THA. This led to 566 primary THA cases being included: 128 unstable, 438 stable. The primary matching factors were sex, age, initial diagnosis, surgical approach, implantation date and type of implants (bearing size, standard or dual-mobility cup). RESULTS: The patients with unstable THAs were 67±12 [37-73]years old on average; there were 61 women (48%) and 67 men (52%). Hip osteoarthritis (OA) was the main reason for the THA procedure in 71% (91/128) of the unstable group. The dislocation was posterior in 84 cases and anterior in 44 cases. The dislocation occurred within 3 months of the primary surgery in 48 cases (38%), 3 to 12 months after in 23 cases (18%), 1 to 5years after in 20 cases (16%), 5 to 10years after in 17 cases (13%) and more than 10years later in 20 cases. The dislocation recurred within 6 months of the initial dislocation in 23 of the 128 cases (18%). The risk factors for instability were a high ASA score with an odds ratio (OR) of 1.93 (95% CI: 1.4-2.6), neurological disability (cognitive, motor or psychiatric disorders) with an OR of 3.9 (95% CI: 2.15-7.1), history of spinal disease (lumbar stenosis, spinal fusion, discectomy, scoliosis and injury sequelae) with an OR of 1.89 (95% CI: 1.0-3.6), unrepaired joint capsule (all approaches) with an OR of 4.1 (95% CI: 2.3-7.37), unrepaired joint capsule (posterior approach) with an OR of 6.0 (95% CI: 2.2-15.9), and cup inclination outside Lewinnek's safe zone (30°-50°) with OR of 2.4 (95% CI: 1.4-4.0). DISCUSSION: This large comparative study isolated important patient-related factors for dislocation that surgeons must be aware of. We also found evidence that implanting the cup in 30° to 50° inclination has a major impact on preventing dislocation. LEVEL OF EVIDENCE: Level III; case-control study.


Subject(s)
Arthroplasty, Replacement, Hip/adverse effects , Arthroplasty, Replacement, Hip/methods , Hip Dislocation/epidemiology , Joint Instability/epidemiology , Adult , Aged , Aged, 80 and over , Case-Control Studies , Female , Health Status , Hip Dislocation/etiology , Hip Prosthesis/adverse effects , Humans , Joint Capsule/surgery , Joint Instability/etiology , Male , Mental Disorders/epidemiology , Middle Aged , Nervous System Diseases/epidemiology , Osteoarthritis, Hip/surgery , Prospective Studies , Risk Factors , Spinal Diseases/epidemiology , Time Factors
9.
Orthop Traumatol Surg Res ; 103(1): 3-7, 2017 02.
Article in English | MEDLINE | ID: mdl-27919767

ABSTRACT

BACKGROUND: Arthroplasty is now widely used to treat intra-capsular proximal femoral fractures (PFFs) in older patients, even when there is little or no displacement. However, whether arthroplasty is associated with lower mortality and complication rates in non-displaced or mildly displaced PFFs is unknown. The objectives of this prospective study were: (1) to evaluate early mortality rates with the two treatment methods, (2) to identify risk factors for complications, (3) and to identify predictors of functional decline. HYPOTHESIS: Arthroplasty and internal fixation produce similar outcomes in non-displaced fractures of patients older than 80 years with PFFs. MATERIAL AND METHODS: This multicentre prospective study included consecutive patients older than 80 years who were managed for intra-capsular PFFs at eight centres in 2014. Biometric data and geriatric assessment scores (Parker Mobility Score, Katz Index of Independence, and Mini-Nutritional Assessment [MNA] score) were collected before and 6 months after surgery. Independent risk factors were sought by multivariate analysis. We included 418 females and 124 males with a mean age of 87±4years. The distribution of Garden stages was stage I, n=56; stage II, n=33; stage III, n=130; and stage IV, n=323. Arthroplasty was performed in 494 patients and internal fixation in 48 patients with non-displaced intra-capsular PFFs. RESULTS: Mortality after 6 months was 16.4% overall, with no significant difference between the two groups. By multivariate analysis, two factors were significantly associated with higher mortality, namely, male gender (odds ratio [OR], 3.24; 95% confidence interval [95% CI], 2.0-5.84; P<0.0001) and high ASA score (OR, 1.56; 95% CI, 1.07-2.26; P=0.019). Two factors were independently associated with lower mortality, with 75% predictive value, namely, high haematocrit (OR, 0.8; 95% CI, 0.7-0.9; P=0.001) and better Parker score (OR, 0.5; 95% CI, 0.3-0.8; P=0.01). The cut-off values associated with a significant risk increase were 2 for the Parker score (OR, 1.8; 95% CI, 1.1-2.3; P=0.001) and 37% for the haematocrit (OR, 3.3; 95% CI, 1.9-5.5; P=0.02). Complications occurred in 5.5% of patients. Surgical site infections were seen in 1.4% of patients, all of whom had had arthroplasty. Blood loss was significantly greater with arthroplasty (311±197mL versus 201±165mL, P<0.0002). Dependency worsened in 39% of patients, and 31% of patients lost self-sufficiency. A higher preoperative Parker score was associated with a lower risk of high postoperative dependency (OR, 0.86; 95% CI, 0.76-0.97; P=0.014). DISCUSSION: Neither treatment method was associated with decreased mortality or better function after intra-capsular PFFs in patients older than 80 years. Early mortality rates were consistent with previous reports. Among the risk factors identified in this study, age, preoperative self-sufficiency, and gender are not amenable to modification, in contrast to haematocrit and blood loss. CONCLUSION: Internal fixation remains warranted in patients older than 80 years with non-displaced intra-capsular PFFs. LEVEL OF EVIDENCE: III, prospective case-control study.


Subject(s)
Arthroplasty, Replacement, Hip/mortality , Femoral Neck Fractures/surgery , Fracture Fixation, Internal/mortality , Aged, 80 and over , Arthroplasty, Replacement, Hip/adverse effects , Blood Loss, Surgical , Case-Control Studies , Female , Femoral Neck Fractures/blood , Follow-Up Studies , Fracture Fixation, Internal/adverse effects , Geriatric Assessment , Hematocrit , Humans , Male , Multivariate Analysis , Prospective Studies , Risk Factors , Sex Factors , Surgical Wound Infection/etiology
10.
Bone Joint J ; 98-B(12): 1620-1624, 2016 Dec.
Article in English | MEDLINE | ID: mdl-27909123

ABSTRACT

AIMS: The role of high tibial osteotomy (HTO) is being questioned by the use of unicompartmental knee arthroplasty (UKA) in the treatment of medial compartment femorotibial osteoarthritis. Our aim was to compare the outcomes of revision HTO or UKA to a total knee arthroplasty (TKA) using computer-assisted surgery in matched groups of patients. PATIENTS AND METHODS: We conducted a retrospective study to compare the clinical and radiological outcome of patients who underwent revision of a HTO to a TKA (group 1) with those who underwent revision of a medial UKA to a TKA (group 2). All revision procedures were performed using computer-assisted surgery. We extracted these groups of patients from our database. They were matched by age, gender, body mass index, follow-up and pre-operative functional score. The outcomes included the Knee Society Scores (KSS), radiological outcomes and the rate of further revision. RESULTS: There were 20 knees in 20 patients in each group. The mean follow-up was 4.1 years (2 to 18.7). The mean total KSS at last follow-up was 185.7 (standard deviation (sd) 5) in group 1 compared with 176.5 (sd 11) for group 2 (p = 0.003). The mean hip-knee-ankle angle was 180.2° (sd 3.2°) in group 1 and 179.0° (sd 2.2°) in group 2. No revision was required. CONCLUSION: We found that good functional and radiological outcomes followed revision of both HTO and UKA to TKA. Revision of HTO showed significantly better functional outcomes. These results need to be further investigated by a prospective randomised controlled trial involving a larger group of patients. Cite this article: Bone Joint J 2016;98-B:1620-4.


Subject(s)
Arthroplasty, Replacement, Knee/methods , Osteoarthritis, Knee/surgery , Osteotomy/methods , Surgery, Computer-Assisted/methods , Aged , Arthroplasty, Replacement, Knee/adverse effects , Female , Follow-Up Studies , Humans , Knee Joint/diagnostic imaging , Knee Joint/physiopathology , Male , Middle Aged , Osteotomy/adverse effects , Radiography , Recovery of Function , Reoperation/adverse effects , Reoperation/methods , Retrospective Studies , Severity of Illness Index , Surgery, Computer-Assisted/adverse effects , Tibia/surgery , Treatment Outcome
11.
Knee Surg Sports Traumatol Arthrosc ; 24(11): 3387-3395, 2016 Nov.
Article in English | MEDLINE | ID: mdl-27585448

ABSTRACT

PURPOSE: The goal of this article is to present our experience on navigation for osteotomies around the knee and especially osteotomies for coronal deformities. The first computer-assisted osteotomy was performed in March 2001 and since that time more than 1000 osteotomies have been performed in our department. METHODS: All the osteotomies were performed with the Orthopilot® device (B-Braun-Aesculap, Tuttlingen, Germany). The main indication was for genu varum deformities but several cases were operated for genu valgum. The surgical procedure as well as the indications and the rationale for each osteotomy (high tibial osteotomy-HTO, double-level osteotomy-DLO, femoral osteotomy-FO) are addressed in the article. RESULTS: The results are focused on several papers published by the authors since more than 10 years. Regarding HTO for genu varum, the preoperative goal (HKA angle: 184° ± 2°) was reached in 96 % of cases and the difference was statistically significant compared to the non-navigated series (71 %: p < 0.05). Regarding DLO for genu varum, the preoperative goal was reached in 92.7 % for the HKA angle and in 88.1 % for the medial proximal tibial mechanical angle (MPTMA). Regarding genu valgum deformity, the preoperative goal was achieved in 86.2 % of cases for the HKA angle and 100 % of cases for the MPTMA. CONCLUSION: According to these results, one can say that, regardless the type of osteotomy, the procedure is reliable, reproducible and accurate. Since 15 years, all the osteotomies around the knee are navigated in our department. Provided that one uses a reproducible radiograph protocol, navigation allows to perform double-level osteotomies, both for genu varum and genu valgum, with optimal accuracy in order to avoid oblique joint line, which will be difficult to revise to TKA. LEVEL OF EVIDENCE: IV.


Subject(s)
Osteoarthritis, Knee/surgery , Osteotomy/methods , Surgery, Computer-Assisted , Adolescent , Adult , Female , Femur/surgery , Fractures, Bone , Genu Valgum/surgery , Genu Varum , Germany , Humans , Knee Joint/surgery , Male , Middle Aged , Radiography , Surgery, Computer-Assisted/methods , Tibia/surgery , Young Adult
12.
Orthop Traumatol Surg Res ; 102(5): 589-93, 2016 09.
Article in English | MEDLINE | ID: mdl-27424096

ABSTRACT

BACKGROUND: Our objective was to evaluate the long-term functional and radiological outcomes of tension band wiring with a single K-wire for acute Rockwood types IV and V acromio-clavicular dislocation (ACD). METHODS: Single-centre cross-sectional non-randomised observational cohort study of 25 shoulders treated surgically between January 2002 and December 2004, in 25 patients, 23 males and 2 females, with a mean age of 35±11years (24-46). The evaluation criteria were the absolute and weighted Constant scores, QuickDASH score, subjective shoulder value (SSV), visual analogue scale (VAS) pain score at rest and during activities, and radiographic features in clinically symptomatic patients. RESULTS: Mean values were as follows: follow-up, 150±17months (133-167); absolute Constant score, 88±17 (71-105); weighted Constant score, 92.5±12.5 (80-105); QuickDASH, 15.5±7 (8.5-22.5); SSV, 88±17% (71-105); VAS pain score at rest, 0.2±0.7 (0-0.9); and VAS pain score while active, 1.4±2.3 (0-3.7). The weighted Constant score was less than 70% in only 8% of patients. Of the 17 patients for whom radiographs were obtained, 8 had acromio-clavicular osteoarthritis. Mean coraco-clavicular distance was 12.3±4.3mm (8-16.6) and mean acromio-clavicular distance was 5±5mm (0-10). The recurrence rate was 8%. CONCLUSION: Tension band wiring with a single K-wire for acute acromio-clavicular dislocation reliably provides good long-term functional outcomes. Recurrences are uncommon and few patients experience symptoms (8%). LEVEL OF EVIDENCE: IV, retrospective study.


Subject(s)
Acromioclavicular Joint/surgery , Bone Wires , Joint Dislocations/surgery , Orthopedic Procedures/methods , Acromioclavicular Joint/diagnostic imaging , Adult , Cross-Sectional Studies , Female , Humans , Joint Dislocations/diagnostic imaging , Male , Middle Aged , Orthopedic Procedures/instrumentation , Radiography , Recovery of Function , Retrospective Studies , Treatment Outcome
13.
Osteoarthritis Cartilage ; 23(11): 1972-80, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26521743

ABSTRACT

OBJECTIVES: Osteoarthritis (OA) is characterized by a progressive alteration of the biochemical properties of the articular cartilage. Inflammation plays a major role in OA, particularly through the cytokine Interleukine-1ß, promoting reactive oxygen species (ROS) generation and matrix metalloproteinases (MMP) synthesis by the chondrocytes, orchestrating matrix proteolysis. NADPH oxidases (NOX) are membrane enzymes dedicated to the production of ROS. Role of oxidative stress is well established in OA; however, contribution of NOX in this process is still poorly documented. In this study, we addressed the role of NOX in primary human articular chondrocytes (HAC) upon inflammatory conditions--namely IL-1ß and OA. DESIGN: HAC were collected from patients undergoing hip surgery. Chondrocytes were treated with IL-1ß and NOX inhibitors Diphenylene Iodonium, GKT136901, Tiron and Heme oxygenase-1 before MMP expression and NOX activity assessment. Finally, NOX4 expression was compared between OA and non OA parts of hip cartilage (n = 14). RESULTS: This study establishes for the first time in human that NOX4 is the main NOX isoform expressed in chondrocytes. We found a significant upregulation of NOX4 mRNA in OA chondrocytes. Expression of NOX4/p22(phox) as well as ROS production is enhanced by IL-1ß. On the other hand, the use of NOX4 inhibitors decreased IL-1ß-induced collagenase synthesis by chondrocytes. Moreover, our study support the existence of a redox dependant loop sustaining pro-catabolic pathways induced by IL-1ß. CONCLUSIONS: This study points out NOX4 as a new putative target in OA and suggests that NOX-targeted therapies could be of interest for the causal treatment of the pathology.


Subject(s)
Gene Expression Regulation , Interleukin-1beta/genetics , Matrix Metalloproteinases, Secreted/metabolism , NADPH Oxidases/genetics , Osteoarthritis, Hip/genetics , Oxazoles/metabolism , Up-Regulation , Aged , Aged, 80 and over , Cartilage, Articular/metabolism , Cartilage, Articular/pathology , Cells, Cultured , Chondrocytes/metabolism , Chondrocytes/pathology , DNA/genetics , Female , Haptens , Humans , Immunohistochemistry , Interleukin-1beta/biosynthesis , Male , Microscopy, Confocal , Middle Aged , NADPH Oxidase 4 , NADPH Oxidases/biosynthesis , Osteoarthritis, Hip/metabolism , Osteoarthritis, Hip/pathology , Real-Time Polymerase Chain Reaction , Transcriptional Activation
14.
Orthop Traumatol Surg Res ; 101(4): 437-41, 2015 Jun.
Article in English | MEDLINE | ID: mdl-25899667

ABSTRACT

BACKGROUND: Large-diameter metal-on-metal hip prostheses are no longer used, but their outcomes after more than 5 years are unknown. We conducted a retrospective study with a 6.8-year mean follow-up to assess clinical outcomes after Durom™ cup implantation, including the dislocation rate, comparatively to the reference metal-on-polyethylene bearing. We determined the rate of failure ascribable to Durom™ cup use. We also looked for a sharp drop in the implant survival curve during the follow-up period and for factors associated with adverse reactions to metal debris (ARMDs). HYPOTHESIS: We hypothesised that clinical outcomes after Durom™ cup implantation were similar to those seen with a metal-on-polyethylene bearing, except for a lower rate of dislocation. PATIENTS AND METHODS: We included 177 consecutive THA procedures that were performed between 2005 and 2008 in 165 patients with a mean age of 57.6 ± 9.4 years (range, 31-76 years) and involved the implantation of a Durom™ cup, a femoral head greater than 36mm in diameter, and a PF(®) femoral stem (Zimmer, Etupes, France). The mini-posterior approach was used, with 2mm of acetabular overreaming in 82% of cases, a short femoral neck in 75% of cases, and a mean cup inclination of 34 ± 5° (range, 21-50°). RESULTS: Outcomes were assessed for 156 THA procedures in 146 patients after a mean follow-up of 6 years 8 months. The mean Postel-Merle d'Aubigné score improved from 9.7 ± 2.7 (range, 4-14) to 17.4 ± 1.7 (range, 15-18) and the mean Harris hip score from 45.2 ± 15.3 (range, 9-83) to 96.3 ± 7 (75-100). No episodes of dislocation were recorded. We identified 7 failures ascribable to the Durom™ cup including 6 due to ARMD and 1 to aseptic loosening. Implant survival after a mean of 80months was 95.5% (95% CI, 93.1-99.2), with no sharp drop in the survival curve. CONCLUSION: The Durom™ cup eliminates the risk of hip dislocation and produces similar functional outcomes to those seen with metal-on-polyethylene bearings after a mean follow-up of 80 months. Nevertheless, given the difficulty in predicting ARMD and hypersensitivity reactions, the Durom™ cup has been discarded and patients carrying it are monitored closely.


Subject(s)
Acetabulum/surgery , Arthroplasty, Replacement, Hip/instrumentation , Femur/surgery , Hip Dislocation/surgery , Hip Prosthesis/statistics & numerical data , Polyethylenes , Acetabulum/diagnostic imaging , Adult , Aged , Female , Femur/diagnostic imaging , Follow-Up Studies , France , Hip Dislocation/diagnostic imaging , Humans , Male , Middle Aged , Prosthesis Design , Radiography , Retrospective Studies , Time Factors
15.
Orthop Traumatol Surg Res ; 101(3): 307-11, 2015 May.
Article in English | MEDLINE | ID: mdl-25771528

ABSTRACT

INTRODUCTION: Acute patellar tendon rupture is easy to diagnose but is still often overlooked. The aim of this study was to assess early and late results of surgical treatment of acute patellar tendon rupture. Our hypothesis was that functional outcome is satisfactory. METHODS: A retrospective study included 38 knees in 37 patients (4 female, 33 male). Mean age was 42.6 ± 9.9 years (range, 23-81 years). Lesions comprised 15 tendon body ruptures, 20 avulsions from the tip of the patella and 3 avulsions from the anterior tibial tuberosity. Tendon repair was protected in more than 95% of cases by a reinforcement frame: hamstring (21 cases), synthetic ligament (12 cases) or metallic wire (3 cases). Results were evaluated in 2 steps: on patient files at a mean follow-up of 7.1 months (range, 3-24 months) to assess complications and early functional and radiological results; and by phone at a mean follow-up of 9.3 years (range, 19-229 months) in order to assess long-term functional outcome on Lysholm score and patient satisfaction. RESULTS: Thirty-one knees were assessed at a mean 7.1 months. Mean knee flexion was 128.5° ± 7.5° (range, 85°-150°), extension -1° (range, -15° to 0°) and Caton-Deschamps index 0.96 (range, 0.57-1.29). Twenty-three knees were further assessed at a mean 9.3 years. Mean Lysholm score was 93.7 points (range, 61-100). Ninety-six percent of patients were satisfied or very satisfied with the result. All had returned to their previous job, and 20 had returned to sports activities, including 8 at pretrauma level. CONCLUSION: Patellar tendon rupture has good prognosis if diagnosis and surgical treatment is early.


Subject(s)
Patellar Ligament/injuries , Patellar Ligament/surgery , Tendon Injuries/surgery , Adult , Aged , Aged, 80 and over , Female , Follow-Up Studies , Humans , Knee Joint/physiopathology , Lysholm Knee Score , Male , Middle Aged , Patella/surgery , Patient Satisfaction , Range of Motion, Articular , Retrospective Studies , Rupture/surgery , Time Factors , Young Adult
16.
Orthop Traumatol Surg Res ; 100(2): 213-6, 2014 Apr.
Article in English | MEDLINE | ID: mdl-24529850

ABSTRACT

INTRODUCTION: Quadriceps tendon ruptures are rare and mainly affect patients over 40 years of age who have a systemic disease. The aim of this study was to evaluate the functional and radiological outcomes following surgical repair of acute quadriceps tendon ruptures. METHODS: This retrospective study included 68 knees in 65 patients (three women, 62 men), having an average age of 55.2 ± 13.9 years. The Lysholm and Tegner scores, patient satisfaction, range of motion and X-rays were evaluated. RESULTS: Fifty knees were evaluated with a mean follow-up of 76±67 months (12-253 months). The average Lysholm score was 93.7±10 (range 56-100, median 99) and 49 of 50 knees (98%) had good or very good subjective results. The average Tegner score was 3.4±1.6 (range 1-9, median 4). At the last follow-up, the average active flexion was 133°±10.8° (range 110°-150°, median 130°). Minor or moderate patellofemoral osteoarthritis was found in 24% of knees, but this was attributed to the surgery or initial injury in only 8% of cases. For 97% of active patients, the surgical repair allowed them to return to work in their pre-injury occupations. CONCLUSION: Quadriceps tendon ruptures have a good prognosis if they are diagnosed quickly. Treatment consists of surgery and postoperative immobilization for at least 6 weeks. An intensive rehabilitation protocol is also needed to recover good knee function. LEVEL OF EVIDENCE: Level IV. Retrospective study.


Subject(s)
Knee Injuries/surgery , Tendon Injuries/surgery , Adolescent , Adult , Aged , Aged, 80 and over , Casts, Surgical , Female , Follow-Up Studies , Humans , Lysholm Knee Score , Male , Middle Aged , Patient Satisfaction , Range of Motion, Articular , Retrospective Studies , Return to Work , Rupture/surgery , Time-to-Treatment , Young Adult
17.
Eur J Orthop Surg Traumatol ; 23(6): 719-23, 2013 Aug.
Article in English | MEDLINE | ID: mdl-23412174

ABSTRACT

Sternoclavicular lesions may sometimes require surgery. Many techniques have been described and they appear to be very demanding. We describe a simple technique using two screws and a strong suture (Arthrex Inc. Naples. FL 34108 USA). Level of evidence; Level IV, Case Series, Treatment Study.


Subject(s)
Joint Dislocations/surgery , Orthopedic Procedures/methods , Sternoclavicular Joint/injuries , Adolescent , Adult , Bone Screws , Humans , Male , Sternoclavicular Joint/surgery , Suture Techniques
18.
Orthop Traumatol Surg Res ; 99(1 Suppl): S67-76, 2013 Feb.
Article in English | MEDLINE | ID: mdl-23352566

ABSTRACT

Rupture of the extensor apparatus of the knee in adults is infrequent and dominated by patellar fracture, which in our experience is six times as frequent as quadriceps or patellar tendon tear. Patellar fracture poses few diagnostic problems and treatment is now well codified. Tension-band osteosynthesis is generally used, involving two longitudinal K-wires and wire in a figure-of-eight pattern looped over the anterior patella; sometimes, for more complex fractures, cerclage wiring is added to the tension band. Non-union is rare and generally well tolerated. Quadriceps tendon tear mainly affects patients over 40 years of age, in a context of systemic disease. Diagnosis is easily suggested by inability to actively extend the knee, but is unfortunately still often overlooked in emergency. In most cases, early surgical management is needed to reinsert the tendon at the proximal pole of the patella by bone suture. For chronic lesions, it is often necessary to lengthen the quadriceps tendon by V-Y plasty or the Codivilla technique. Patellar tendon tear, on the other hand, typically occurs in patients under 40 years of age, often involved in sports. Diagnosis is again clinically straightforward, but again may be missed in emergency, especially in case of incomplete tear. Surgery is mandatory in all cases. The procedure depends on the type of lesion: either end-to-end suture or transosseous reinsertion. In most cases repair is protected by tendon augmentation. Old lesions often require tendon graft or a tendon-bone-tendon-bone graft taken from the opposite side.


Subject(s)
Fractures, Bone/complications , Patella/injuries , Patellar Ligament/injuries , Tendon Injuries/etiology , Adult , Fractures, Bone/diagnosis , Fractures, Bone/surgery , Humans , Orthopedic Procedures/methods , Quadriceps Muscle , Tendon Injuries/diagnosis , Tendon Injuries/surgery
19.
Orthop Traumatol Surg Res ; 98(6): 684-9, 2012 Oct.
Article in English | MEDLINE | ID: mdl-22986015

ABSTRACT

INTRODUCTION: Surgical site infections (SSI) studies rely on an imprecise and debatable definition. The term "wound healing problems" (WHP), not necessarily septic, is also frequently cited. This study had the objectives of determining the frequency of early SSIs in traumatology, these terms eventual correlation, and the factors influencing onset. PATIENTS AND METHODS: A multicenter prospective observational study was conducted in 12 centers. The exclusion criteria were open lesions as well as multiple injuries and multiple fractures (more than two fractures treated surgically). All patients were followed for the first three postoperative months until there was clinical certainty of healing and absence of infection. The presence of any WHP or SSI required a minimum follow-up of 1 year. WHP and SSI risk factors were determined using logistical regression adjusted on the centers. RESULTS: Out of 1617 cases, 103 were complicated by a WHP and 22 by a SSI. The SSIs were mainly secondary to Staphylococcus infections. The factors predisposing the patients to WHP and SSI (p≤0.05) were age; the NNIS, ASA, and Parker scores; alcoholism; antiaggregant use; and the locoregional aspect at the time of injury. The 522 subcutaneous osteosyntheses "near the skin" resulted in 58 WHPs (11%) and 14 SSIs (2.7%); 13 of the 58 WHPs (22%) resulted in one SSI. Out of 707 deep osteosyntheses, 24 (3.4%) presented a WHP and seven (1%) a SSI; Four SSIs originated from a WHP. The 352 fractures of the trochanter were complicated by a WHP in 15 cases (5.5%) and a SSI in one case (0.4%) after interlocked nailing and two WHPs and two SSIs (2.5%) after screw and plate fixation. Of the 388 first-line arthroplasties, only the prostheses implanted for a proximal femur fracture presented complications: 21 WHPs (6%) and one SSI (0.02%). Of the 103 WHPs of the entire series, 18 became SSIs. In absence of WHP, the SSI rate was 0.2%, whereas the probability of a WHP evolving toward a SSI was 100 times higher. The only factor significantly associated with a WHP becoming a SSI was osteosynthesis material exposure. DISCUSSION: This prospective study can be criticized on several points: the deliberately limited inclusion criteria, the short follow-up, and the possible subjectivity of the data collection. The SSI rates reported are for the most part in agreement with the literature. This study is innovative in traumatology given the large number of patients and the notion of WHP that was preferred over superficial infection. It demonstrates the relations between WHP and SSI, in particular for osteosyntheses near the skin. LEVEL OF EVIDENCE: Level III.


Subject(s)
Fracture Fixation/adverse effects , Fractures, Bone/surgery , Surgical Wound Infection/etiology , Trauma Centers/statistics & numerical data , Adult , Fracture Healing , France/epidemiology , Humans , Incidence , Prospective Studies , Risk Factors , Surgical Wound Infection/diagnosis , Surgical Wound Infection/epidemiology , Time Factors
20.
Orthop Traumatol Surg Res ; 97(8): 886-9, 2011 Dec.
Article in English | MEDLINE | ID: mdl-22048070

ABSTRACT

Management of lower limb fractures in children involves many approaches, spanning from conservative treatment to open reduction and internal fixation. A number of intermediate treatments have also been shown to be effective, notably skeletal traction. However, each of these techniques has its own advantages and disadvantages in terms of complications. In this report, we describe two new cases of chronic osteomyelitis that manifested (many years) after childhood skeletal traction. After analysing these two cases, we proposed measures that can be implemented to avoid such complications, along with a simple, appropriate, reproducible treatment approach.


Subject(s)
External Fixators/adverse effects , Fracture Fixation/adverse effects , Osteomyelitis/etiology , Tibial Fractures/therapy , Adult , Anti-Bacterial Agents/therapeutic use , Biopsy , Chronic Disease , Debridement/methods , Diagnosis, Differential , Follow-Up Studies , Fracture Fixation/methods , Humans , Magnetic Resonance Imaging , Male , Osteomyelitis/diagnosis , Osteomyelitis/therapy , Staphylococcal Infections/diagnosis , Staphylococcal Infections/etiology , Staphylococcal Infections/therapy , Staphylococcus aureus/isolation & purification , Tibial Fractures/diagnosis
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