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Can Med Assoc J ; 106(11): 1175-9, 1972 Jun 10.
Article in English | MEDLINE | ID: mdl-5034698

ABSTRACT

During the summer of 1971, the first laboratory-proved cases of acute encephalitis in man due to any of the known arboviruses occurred in the south-central region of British Columbia. Five human cases of encephalitis with two deaths were diagnosed; three of these patients, including one of the fatalities, were proven in the laboratory to have contracted western equine encephalitis.During 1968 and 1969, a human serum survey undertaken in approximately 2000 life-long residents of the province discovered low levels of hemagglutinin-inhibiting and/or complement-fixing as well as neutralizing antibodies for western equine encephalitis, St. Louis encephalitis, Powassan encephalitis, California encephalitis and Colorado tick fever. Evidence of recent sub-clinical infection was detected in some cases.


Subject(s)
Arbovirus Infections/epidemiology , Encephalomyelitis, Equine/epidemiology , Adolescent , Adult , Animals , Arboviruses/immunology , Brain/microbiology , British Columbia , Child , Colorado Tick Fever/epidemiology , Colorado Tick Fever/immunology , Complement Fixation Tests , Encephalitis Virus, St. Louis/immunology , Encephalitis Virus, Western Equine/immunology , Encephalitis Virus, Western Equine/isolation & purification , Encephalitis, Arbovirus/epidemiology , Encephalitis, Arbovirus/immunology , Encephalomyelitis, Equine/immunology , Female , Hemagglutination Inhibition Tests , Horses , Humans , Male , Neutralization Tests
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