ABSTRACT
BACKGROUND: A growing need exists to ensure safe and skilled oncology nursing care for an increasing number of patients enrolled in phases 1 and 1/2 clinical trials and to provide detailed adherence to protocol administration. This can be best accomplished in a dedicated area for patients in early phase clinical trials. OBJECTIVES: Nursing standards and practice within a newly established translational research unit at an academic medical center were developed. METHODS: A portion of an existing outpatient infusion room composed of 13 beds and a sub-waiting room with 2 chairs was designated for placement of patients enrolled in early phase clinical trials. The functional and safety requirements needed to successfully care for these patients while meeting the demands of the trial protocol drove the creation of this dedicated unit. FINDINGS: Development of dedicated space provided opportunities to define the role of the nurse and hardwire patient and staff safety practices that assisted in reducing study deviations.
Subject(s)
Clinical Trials as Topic/standards , Guideline Adherence , Oncology Nursing/standards , Patient Participation , Treatment Adherence and Compliance , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Translational Research, BiomedicalABSTRACT
BACKGROUND: The lack of knowledge and standardization of safety practices related to prescribing, dispensing, administering, and monitoring oral agents for cancer (OACs) has created significant safety challenges for patients and healthcare providers. Problems identified with the use of OACs include possible medication errors, increased potential for toxicity, unintentional exposure of hazardous medications to healthcare providers and informal caregivers, and possible pollution of the environment. OBJECTIVES: The purpose of this review is to provide information about the current state of knowledge and recommendations in the literature regarding safety concerns with OACs and strategies for risk reduction. METHODS: Articles published from 2003-2014 were retrieved using PubMed, CINAHL®, and the Cochrane Library. FINDINGS: As the number of OACs continues to increase, existing standards related to medication errors and safety will require ongoing revision to lessen the risks and hazards for patients, caregivers, and healthcare providers.
