ABSTRACT
OBJECTIVE: Four additional cases of nephrogenic adenoma are described. METHODS: The clinical records of patients with nephrogenic adenoma that had been diagnosed at our hospital from 1994 to 1999 were reviewed. RESULTS: The most frequent localization was the urinary bladder and it was more prevalent in middle-aged men. This condition usually presented as a histological finding in the course of follow-up or treatment of other bladder conditions by TUR or cystectomy. Biopsy is fundamental for diagnosis. CONCLUSIONS: Nephrogenic adenoma is a rare benign metaplastic lesion of the urinary tract that appears to result from chronic irritative stimulus to the urothelium. The treatment of choice is by transurethral resection. Although no case of progression to malignancy have been detected, long-term follow-up by endoscopy and ultrasound is advocated due to its predispositon to recurrence.
Subject(s)
Adenoma/pathology , Urologic Neoplasms/pathology , Female , Humans , Male , Middle AgedABSTRACT
El adenoma pleomorfo es el tumor benigno más común de todas las neoplasias de glándulas salivares, representando el 65 por ciento de todos los tumores de estas localizaciones, afectando sobre todo a la parótida. Puede aparecer también en otras glándulas salivares mayores y menores del tracto aerodigestivo superior.Presentamos dos casos de adenomas localizados en tabique nasal y paladar blando, señalando las características clínicas y diagnósticas de nuestros pacientes, así como la terapéutica aplicada.Exponemos los aspectos más importantes de esta entidad en el momento actual (AU)
Subject(s)
Adult , Female , Male , Middle Aged , Humans , Salivary Glands, Minor/surgery , Salivary Glands, Minor/pathology , Adenoma, Pleomorphic/surgery , Adenoma, Pleomorphic/complications , Adenoma, Pleomorphic/diagnosis , Adenoma, Pleomorphic , Salivary Gland Neoplasms/surgery , Salivary Gland Neoplasms/complications , Salivary Gland Neoplasms/diagnosis , Salivary Gland Neoplasms/etiology , Neoplasm Invasiveness/pathology , Tomography, X-Ray Computed/methods , Tomography, X-Ray Computed , Neoplasm Metastasis , Nasal Septum/surgery , Nasal Septum/pathologyABSTRACT
INTRODUCTION: Presentation of adenocarcinoma of the prostate as an intracranial metastasis is uncommon. This metastasis tends to be seen in the sphenoid bone, and in this case it is difficult to differentiate radiologically from a meningioma. Because this cancer is treatable, the differential diagnosis must be resolved as soon as possible. CLINICAL CASE: A 72 year old man presented with a rapidly progressive left parasellar syndrome. On neuroimaging there was a tumour at the level of the left lesser wing of the sphenoid, which was isodense and iso-intense and also showed homogeneous uptake of contrast material. On angiography the circulation was pathological with homogeneous delayed filling. The initial diagnosis was meningioma of the lesser wing of the sphenoid. Months later the patient complained of bone and respiratory problems. At this time plain chest X-ray was compatible with carcinomatous lymphangitis. Therefore, tumour markers were studied and for the first time the specific prostatic antigen was investigated and found to be raised. Although there were no symptoms of prostatism, per rectum there was a malignant prostatic mass. In spite of complete hormone block, his illness followed an unfavorable course. At necropsy there was adenocarcinoma of the papillary prostate and a metastasis in the left lesser wing of the sphenoid. CONCLUSIONS: In elderly men, detection of a sphenoid tumour, which radiologically may appear to be a meningioma and although prostatism has not been diagnosed, the possibility of prostatic metastasis should be considered. Per rectum examination and specific prostatic antigen determination should be done in these patients.
