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Cryobiology ; 115: 104886, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38555011

ABSTRACT

Nowadays, the physical nature of supersaturated binary aqueous sugar solutions in the vicinity of the glass transition represents a very important issue due to their biological applications in cryopreservation of cells and tissues, food science and stabilization and storage of nano genetic drugs. We present the construction of the Supplemented Phase Diagram and the non-equilibrium nature of the undersaturated-supersaturated kinetic transition. The description of its thermodynamic nature is achieved through the study of behavior of their viscosity as temperature is lowered and concentration increased. In this work, we find a universal character for the viscosities of several sugar water solutions.


Subject(s)
Cryopreservation , Vitrification , Water , Viscosity , Cryopreservation/methods , Water/chemistry , Sugars/chemistry , Cryoprotective Agents/chemistry , Cryoprotective Agents/pharmacology , Thermodynamics , Phase Transition , Solutions , Sucrose/chemistry , Trehalose/chemistry , Temperature
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