[Brooke-Spiegler syndrome]. / Syndrome de Brooke-Spiegler.

BACKGROUND: Brooke-Spiegler syndrome is an association of multiple trichoepitheliomas and cylindromas, sometimes accompanied by other adnexal tumors. CASE REPORT: A 44-year-old woman with trichoepitheliomas involving the naso-genal and mental areas associated with cylindromas and spiradenomas on the forehead and pretragal regions creating a turban effect. Other complete or diassociated syndromes were found in family members. No neoplastic tumor was identified. DISCUSSION: Brooke-Spiegler syndrome is an hereditary disease with autosomal dominant transmission. Both benign and malignant neoplasias can be associated. The concomitant existence of different tumors could be helpful in understanding the pathophysiology. There is some debate about the exact origin of the trichoepitheliomas, cylindromas and spiradenomas. Several single-cause theories have been put forward but remain to be confirmed as the genetic anomalies identified for trichoepitheliomas and cylindromas map to different sites. Patients with Brooke-Spiegler syndrome should be explored for malignant neoplasia. A family study is indicated.

[Idiopathic eruptive macular pigmentation following pityriasis rosea. Presentation of two cases (author's transl)]. / "Pigmentation éruptive maculeuse idiopathique" au décours d'un pityriasis rosé de Gibert. Présentation de 2 observations.

We describe two cases of acquired hyperpigmented macular eruption following pityriasis rosea. This condition is characterized by an eruption of discrete grayish macules on the trunk. On the back, the lesion are oval and their long axis follows the cutaneous liners. Similar features have been described by Runtova. The clinical type of this pigmented eruption is quite comparable to the cases recently described by Degos, Civatte and Belaïch under the title of "idiopathic eruptive macular pigmentation". Sometimes the "idiopathic" character of this pigmented eruption may be lacking, when a retrospective diagnosis of lichen planus or pityriasis rosea can be made. We think that the pigmentogenes pityriasis rosea should be included in the group of atypical pityriasis rosea. A survey of the literature allows to recognize some identical cases formerly reported under various titles. All these cases should be grouped together under the title of pigmentogenes pityriasis rosea.

[Acne-like eruption induced by pseudo-xanthoma elasticum (author's transl)]. / Lésions acnéiformes induites par le pseudo-xanthome élastique.

Pseudoxanthoma elasticum can induce acne-like eruption. The lesions are located on the latero-cervical parts and consist of comedones, cysts and inflammatory nodules. Histologically, there are no transepithelial eliminations or follicultitis, but a very important granulomatosus tissue with epithelioid cells and a giganto-cellular reaction with elastotic fibres phagocytosis. These findings are different from the cases with association of P.X.E. and elastosis perforans, but they are closely related to it. We think that these features are of a very great interest for the dermatological practice.

[Dermatomyositis with spinulosis (Wong type dermatomyositis). Histologic study. Attempt at pathogenic interpretation]. / Dermatomyosite avec spinulosisme (dermatomyosite type Wong). Etude histologique. Essai d'interprétation pathogénique

The authors present a case of dermatomyositis with generalised spinulosis of pilose pityriasis rubra (lichen ruber acuminatus) type, giving a highly characteristic appearance of linear verruciform spinulosis of the back of the hands. They describe the histological lesions and feel that this spinulosis is probably due to marked degenerative smooth muscle myositis of the erector pili muscles. They recall the earlier cases of O'Leary and Christianson and above all those of Wong. The case reported is the first in a child.