ABSTRACT
Combined influence of detsius, sodium nitrate, total x-irradiation, and radon inhalations on rat skin was investigated. Preliminary irradiation of rats in a dose 100 R and 4-hour radon inhalation in concentration 8.1 x 10(7) Bq/m3 did not amplify detsius and sodium nitrate effects in LD50 doses. Detsius intake in 10- and 50-fold doses 5 times a week induced focal alopecia in a week. A conclusion is made on the necessity of prohibiting detsius use in practical agriculture.
Subject(s)
Alopecia/etiology , Insecticides/toxicity , Pyrethrins/toxicity , Radiation Injuries, Experimental/etiology , Skin/drug effects , Skin/radiation effects , Animals , Carcinogens/toxicity , Dose-Response Relationship, Drug , Insecticides/pharmacology , Male , Nitrates/toxicity , Nitriles , Pyrethrins/pharmacology , Radiation Dosage , Radon/toxicity , Rats , Time FactorsSubject(s)
Hair/drug effects , Insecticides/toxicity , Pyrethrins/toxicity , Skin/drug effects , Animals , Hair/pathology , Hair Diseases/chemically induced , Hair Diseases/pathology , Male , Nitriles , Rats , Skin/pathology , Skin Diseases/chemically induced , Skin Diseases/pathology , Sodium Nitrite/toxicityABSTRACT
In 1981-1987, 595 outpatient cases of cancer of various sites underwent radiotherapy at the Regional Oncological Dispensary, Chelyabinsk, which saved 317181.25 rubles. The effectiveness of treatment proved similar to that in inpatients. However, the outpatients were characterized by better psycho-social status.
Subject(s)
Neoplasms/radiotherapy , Costs and Cost Analysis , Humans , Inpatients , Neoplasms/economics , Neoplasms/psychology , Outpatients , Socioeconomic FactorsSubject(s)
Air Pollutants/toxicity , Butanols/toxicity , Animals , Maximum Allowable Concentration , Mice , Rats , Time FactorsABSTRACT
Experiments were conducted on male albino rats for 5 months; the activity of the liver aspartic and alaninaminotransferases underwent cyclic synchronized variations. Chronic 24-hour inhalation of vinylacetate in a concentration of 2.4 mg/m3 caused a transformation of the rhythms of these variations with the preservation of synchronization in the changes of the activity of the enzymes under study. With a greater concentration of vinylacetate (13.2 and 68 mg/m3) inducing chronic intoxication, desynchronization of transaminase variations was seen in the liver. A posssibility of correlation analysis use for determining the extent of synchronization in the activity of the enzymatic systems for the purpose of estimation of the toxic effect of the poisons is discussed.
