ABSTRACT
AIM: To analyse the correlations between clinical and MRI sacroiliitis activity indices in ankylosing spondylitis (AS). MATERIALS AND METHODS: Sixteen normal volunteers and 52 patients were enrolled. The clinical AS activity indices included the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) score, serum high-sensitivity C-reactive protein, and erythrocyte sedimentation rate. The MRI sacroiliitis activity indices included apparent diffusion coefficient (ADC) values of bone and the Spondyloarthritis Research Consortium of Canada (SPARCC) score. RESULTS: The mean SPARCC score of the control group was 0 and of the AS group was 9.9 ± 9.1 (range 0-36). The mean ADC value of the AS group was statistically significantly higher than that of the control group (49.7 ± 20.2 × 10(-5)mm(2)/s versus 38.9 ± 5.3 × 10(-5)mm(2)/s, p < 0.05). The BASDAI score showed a statistically significant correlation with the SPARCC score (r = 0.685, p < 0.05) and with ADC values (r = 0.329, p < 0.05). ADC values correlated with the SPARCC score (r = 0.390, p < 0.05). CONCLUSION: ADC values and the SPARCC index may be useful activity indices in AS.
