1.
J Pharm Sci
; 67(11): 1553-7, 1978 Nov.
Article
in English
| MEDLINE
| ID: mdl-712591
ABSTRACT
A simple radioimmunoassay was developed for the determination of oxfendazole in plasma. Oxfendazole N-1(3)-valerate was coupled to polylysine via a carbodiimide reaction, and antiserum was developed in rabbits after inoculation with oxfendazole--polylysine conjugate. The assay was developed so that oxfendazole could be measured directly in a 0.1-ml aliquot of diluted or undiluted plasma. With the developed procedure, 200 pg of oxfendazole/ml of plasma can be determined quantitatively. Cross-reactivity was determined for closely related compounds and metabolites. The method was used to determine plasma concentration--time profiles in dogs and calves.
Subject(s)
Antinematodal Agents/blood , Benzimidazoles/blood , Carbamates/blood , Animals , Antibody Specificity , Cattle , Dogs , Horses , Methods , Plasma/analysis , Radioimmunoassay
2.
Chem Pharm Bull (Tokyo)
; 20(7): 1457-66, 1972 Jul.
Article
in English
| MEDLINE
| ID: mdl-4640447
Subject(s)
Anti-Inflammatory Agents/metabolism , Propionates/metabolism , Administration, Oral , Animals , Anti-Inflammatory Agents/administration & dosage , Capsules , Dogs , Humans , Injections, Intravenous , Methyl Ethers/metabolism , Naphthalenes/administration & dosage , Naphthalenes/metabolism , Propionates/administration & dosage , Suspensions , Tablets
3.
Bull Parenter Drug Assoc
; 26(3): 114-28, 1972.
Article
in English
| MEDLINE
| ID: mdl-5035116
Subject(s)
Adsorption , Powders , Benzalkonium Compounds , Glass , Prednisone , Surface Properties , Suspensions , Technology, Pharmaceutical
4.
Vet Med Small Anim Clin
; 65(6): 597-600, 1970 Jun.
Article
in English
| MEDLINE
| ID: mdl-5201336
5.
J Pharm Sci
; 58(5): 582-5, 1969 May.
Article
in English
| MEDLINE
| ID: mdl-4240330
