ABSTRACT
Objective To evaluate the value of ambulatory blood pressure monitoring in evaluating hypertension status and the efficacy of antihypertensive medication in hypertension patients.Methods We retrospectively collected data from 236 elderly hypertensive patients at our hospital from July 2016 to June 2017 and analyzed the blood pressure characteristics of patients under 24 h ambulatory blood pressure monitoring and the effects of different types of antihypertensive medication.Results Of 236 patients with high blood pressure,80.1％ had both higher systolic blood pressure and higher diastolic blood pressure;about 90.0％ had blood pressure load greater than 40.0％;blood pressure in 57.6％ of patients reached its peak both in the morning and in the afternoon;a majority (58.9％)showed a non dipper circadian pattern.After antihypertensive drug treatment,the blood pressure indicators significantly improved(P ＜0.05).Common antihypertensive drugs included calcium antagonists,angiotensin converting enzyme inhibitors (ACEI),angiotensin receptor blockers (ARB),diuretics,beta blockers,and combination drugs.Conclusions 24 h ambulatory blood pressure monitoring can provide comprehensive blood pressure data,help achieve accurate assessment of blood pressure status,and may be used in the evaluation of antihypertensive drug treatment.
ABSTRACT
Objective To investigate the effects of Gegenqinlian Decoction on the IL-1β level in the patients with chronic periodontitis.Methods Seventy patients with chronic periodontitis were divided into the observation group and control group,35 cases in each group.The control group was given the periodontal basic treatment.On the basis of the control group,the observation group was given Gegenqinlian Decoction.The probing depth,attachment level and bacterial plaque index level before and after treatment were compared between the two groups.The levels of IL-1β and IL-6 in serum and gingival crevicular fluid were measured before and after treatment in the two groups.Results The total effective rate in the observation group was 94.29%,which was significantly higher than 71.43% in the control group,the difference was statistically significant (χ2=6.437,P<0.05).After treatment,the probing depth,attachment level and bacterial plaque index in the two groups were significantly decreased (P<0.05),but which in the observation group were significantly lower than those in the control group,the difference was statistically significant (P<0.05).The levels of IL-1β and IL-6 in serum and gingival crevicular fluid after treatment in the two groups were decreased significantly (P<0.05),but which in the observation group were significantly lower than those in the control group,the difference was statistically significant (P<0.05).Conclusion Gegenqinlian decoction can significantly reduce the IL-1β level in the patients with chronic periodontitis,reduces inflammation reaction and improves the therapeutic effect.
