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Org Biomol Chem
; 17(7): 1787-1790, 2019 02 13.
Article
in English
| MEDLINE
| ID: mdl-30483696
ABSTRACT
Herein we describe the direct enantioselective Lewis base/Pd catalysed α-allylation of pyrrole acetic acid esters. This provides high isolated yields of highly enantioenriched products and exhibits broad reaction scope with respect to both reaction partners. The products can be readily elaborated in a manner which points towards potential applications in target directed synthesis.