ABSTRACT
Acute disseminated encephalomyelitis (AEM) and acute transverse myelitis (OPM) are autoimmune demyelinating diseases of the central nervous system. Two clinical observations of AEM and OPM developed after suffering acute coronavirus infection (SARS-CoV-2) are presented. Differential diagnosis was carried out with multiple sclerosis, encephalitis of an infectious nature, compressive myelopathy, and opticomyelitis. Both observations show an almost complete recovery of lost functions. The pathogenetic mechanisms of the development of AEM and OPM in patients with coronavirus infection are discussed. The onset of central nervous system dysimmune lesion in the context of coronavirus infection makes it necessary to monitor the clinical situation with the involvement of a neurologist for timely diagnosis and determination of therapeutic tactics that can reduce the degree of disability of patients.
Subject(s)
COVID-19 , Encephalomyelitis, Acute Disseminated , Myelitis, Transverse , Nervous System Diseases , Humans , COVID-19/complications , COVID-19/diagnosis , Encephalomyelitis, Acute Disseminated/diagnosis , Encephalomyelitis, Acute Disseminated/etiology , Encephalomyelitis, Acute Disseminated/drug therapy , Myelitis, Transverse/diagnosis , Myelitis, Transverse/etiology , Myelitis, Transverse/drug therapy , SARS-CoV-2ABSTRACT
The authors analyse the results of examination and treatment of 25 patients presenting with occlusive and stenotic lesions of lower-limb arteries accompanied by pronounced concomitant pathology and undergoing minimally invasive endovascular interventions. Comprehensive clinical and instrumental methods of examination (ultrasound duplex scanning, roentgen contrast angiography, multispiral computed tomography with intravenous contrasting) made it possible to work out an algorithm of surgical policy. Patency after endovascular transcutaneous balloon angioplasty and/or stenting by the end of the third year of follow up amounted to 64%, with a limb salvage rate of 68% (17 patients).
