ABSTRACT
PURPOSE: In the United States (US), individuals vary widely in their readiness to get vaccinated for COVID-19. The present study developed measures based on the transtheoretical model (TTM) to better understand readiness, decisional balance (DCBL; pros and cons), self-efficacy (SE), as well as other motivators for change such as myths and barriers for COVID-19 vaccination. DESIGN: Cross-sectional measurement development. SETTING: Online survey. SAMPLE: 528 US adults ages 18-75. MEASURES: Demographics, stage of change (SOC), DCBL, SE, myths, and barriers. ANALYSIS: The sample was randomly split into halves for exploratory factor analysis using principal components analysis (EFA/PCA), followed by confirmatory factor analyses (CFA) to test measurement models. Correlation matrices were assessed and multivariate analyses examined relationships between constructs and sub-constructs. RESULTS: For DCBL, EFA/PCA revealed three correlated factors (one pros, two cons) (n1 = 8, α = .97; n2 = 5, α = .93; n3 = 4, α = .84). For SE, two correlated factors were revealed (n1 = 12, α = .96; n2 = 3, α = .89). Single-factor solutions for Myths (n = 13, α = .94) and Barriers (n = 6, α = .82) were revealed. CFA confirmed models from EFAs/PCAs. Follow-up analyses of variance aligned with past theoretical predictions of the relationships between SOC, pros, cons, and SE, and the predicted relationships with myths and barriers. CONCLUSION: This study produced reliable and valid measures of TTM constructs, myths, and barriers to understand motivation to receive COVID-19 vaccination that can be used in future research.
Subject(s)
COVID-19 Vaccines , COVID-19 , Adult , Humans , United States , Transtheoretical Model , Motivation , Cross-Sectional Studies , Decision Making , COVID-19/prevention & control , Surveys and Questionnaires , Self Efficacy , VaccinationABSTRACT
May 2016 marks the 220th anniversary of Edward Jenner's first experimental vaccination using cowpox to protect against smallpox. Jenner's discovery, and its rapid adoption around the world, launched a medical revolution that continues to shape how we approach disease prevention. The historical roots of vaccination are found in the popularization of smallpox inoculation during the 18th century, part of an Enlightenment culture that fostered scientific inquiry and the global circulation of knowledge. Jenner was part of that culture and his study of cowpox stemmed from his varied interests as a natural historian, his contacts with leading savants in London, and his medical practice in a flourishing dairy area of England. The amazingly quick spread of vaccination resulted from organized hospital trials in major cities, the severe smallpox epidemic at the turn of the century, disease environment, and policies of European colonial powers.
Subject(s)
Smallpox Vaccine/administration & dosage , Smallpox/prevention & control , Vaccination/history , England , History, 18th Century , HumansABSTRACT
SUMMARY: The introduction of smallpox vaccination after the publication of Edward Jenner's An Inquiry into the Causes and Effects of Variolae Vaccinae depended on the spread of cowpox, a relatively rare disease. How Europeans and their colonial allies transported and maintained cowpox in new environments is a social and technological story involving a broad range of individuals from physicians and surgeons to philanthropists, ministers, and colonial administrators. Putting cowpox in new places also meant developing new techniques and organizations. This essay focuses on the actual practices of vaccination and their environmental contexts in order to illuminate the dynamic exchanges of materials, images, and ideas that made the spread of vaccination possible.
Subject(s)
Cowpox/history , Smallpox Vaccine/history , Smallpox/history , Vaccination/history , Animals , Cattle , History, 18th Century , History, 19th Century , Humans , Philately/history , Smallpox/immunology , Smallpox/prevention & control , Vaccination/methodsABSTRACT
Between 1799 and 1806, trials of vaccination to determine its safety and efficacy were undertaken in hospitals in London, Paris, Vienna, and Boston. These trials were among the first instances of formal hospital evaluations of a medical procedure and signal a growing acceptance of a relatively new approach to medical practice. These early evaluations of smallpox vaccination also relied on descriptive and quantitative accounts, as well as probabilistic analyses, and thus occupy a significant, yet hitherto unexamined, place in the history of medical statistics.
