ABSTRACT
A case is reported of permanent sensorimotor distal polyneuropathy combined with sensory hemisymptoms in a middle-aged woman after only 10 g of metronidazole given as 400 mg, three times daily for 9 d. The disability is still permanent after 22 months of observation. No other cause has been found.
Subject(s)
Metronidazole/adverse effects , Peripheral Nervous System Diseases/chemically induced , Chronic Disease , Disability Evaluation , Female , Follow-Up Studies , Humans , Metronidazole/therapeutic use , Middle Aged , Nervous System Diseases/chemically induced , Nervous System Diseases/physiopathology , Peripheral Nervous System Diseases/physiopathology , Risk Assessment , Severity of Illness IndexABSTRACT
Molecular genetic techniques have increased the number of species recognized within the genus Mycobacterium. The clinical significance of these is uncertain and their pathogenic potential has still to be proven. We describe here a case of mycobacterial lymphadenitis in a Swedish boy, which supports the role of M. interjectum as a human pathogen.
Subject(s)
Lymphadenitis/microbiology , Mycobacterium Infections/microbiology , Mycobacterium/classification , Child, Preschool , DNA, Bacterial/analysis , DNA, Bacterial/genetics , DNA, Ribosomal/analysis , DNA, Ribosomal/genetics , Humans , Male , Mycobacterium/genetics , Polymerase Chain Reaction , RNA, Ribosomal, 16S/genetics , Sequence Analysis, DNAABSTRACT
Serologically verified indigenous Q fever is described in a 52-y-old male, who presented with persistent fever, muscle and joint pain, headache and non-purulent cough. Institution of doxycycline resulted in prompt recovery. Coxiella burnetii was isolated from mouldy hay in a barn. The strain differs from previously isolated ones in Sweden.
