[A comparaison between the total PSA, the Gleason score and the bone scintiscan results for different age groups]. / O comparatie între valoarea PSA total, scorul Gleason si rezultatele scintigrafiei osoase la diferite grupe de vârsta.

UNLABELLED: The aim of the study is to compare de results of the bone scintigraphy of prostate cancer patients in different age groups with their total PSA (PSAt) and with their histopathological test results. MATERIALS AND METODS: Of the 180 patients with prostate cancer who were analyzed by Scintiscan in the last five years in our laboratory, 86 have a known PSAt value, and of these, 55 have a known Gleason Score. The 180 patients were divided into three age groups: (1) < or equal 60 years; (2) 60-70 years and (3) >70 years. The 86 patients with a known PSAt were also divided into five groups according to their PSAt value and the 55 patients with a known Gleason Score were divided in three groups. The scintigraphy results included all the patients in 3 groups, according to the presence, the absence or the likelihood of having bone metastasis. The 33 patients with proven bone metastasis were divided, according to their numbers, into the four Soloway groups. RESULTS: Among the patients with PSAt >20 ng/mL, considered high risk for bone metastases, according to the Recomandations of CCAF, 21 (32.81%) of the 64 patients do not show the presence of bone metastases. For PSAt >50 ng/mL, all 5 patients <60 years of age have metastases, while only 15 (62.5%) of the 24 patients over 70 years old have metastases and 1 (4%) has low likelihood. 6 (21.42%) of the 28 patients with PSAt > sau egal 100 ng/mL do not have metastases. 10 (43.4 %) of the 23 patients with a Gleason Score <7, considered low risk, do have metastases (6 patients--26%) or low probability of metastases (4 patients--17.4%). CONCLUSIONS: Our study confirms that the probability of bone metastasis for a high PSAt value is reversely proportional to age. In our study there is no direct correlation between Gleason Score and the bone scan results.

[Specifics of strabismus surgery in adults]. / Particularitatile chirurgiei strabismului la adult.

PURPOSE: To demonstrate that surgical approach in adult's strabismus offers not only cosmetic improvement, but also functional psychosocial benefits. MATERIAL AND METHODS: 19 eyes from 17 patients operated in Eye Clinic, Iasi, between January 2002 and June 2004, with a follow up of 12 months, were enrolled in a retrospective study. Data regarding the history of the disease (onset, cause of deviation, previous treatments), ophthalmological examination (visual acuity, binocularity, deviation), type and the results of surgical interventions were evaluated. RESULTS: Patients ranged in age from 16 to 71 years (mean 30). More than half were in the third decade. This aspect explain the option in choosing surgical treatment for two motivations: esthetic and to increase social interactions. 15 patients have strabismus since childhood and 3--associated with other ocular abnormalities. In 2 patients, the deviations installed at visual maturity as a consequence of sensorial deprivation (age related cataract, aphakia). There were 12 cases with exodeviation and 7 with esodeviations. Surgical approach consisted in resection (42.95% esodeviations, 58.33% exodeviations), recession (14.1% esodeviations, 25% exodeviations), resection-recession (42.95% esodeviations, 16.66 exodeviations). Postoperatively, we encountered successful ocular alignment in 73% cases 6 months later. We observed an increase of binocularity only in 4 patients. CONCLUSIONS: Our data proved that surgical approach in adults' strabismus have, not only cosmetic and psychosocial benefits, but also functional improvement too.