ABSTRACT
The authors describe the case of a 7 year old boy who presented an intestinal intussusception due to a large jejunal hamartomatous jejunal polyp. The preoperative diagnosis of Peutz-Jeghers syndrome was based on typical mucocutaneous pigmentation and confirmed by radiological examination including computerized tomography of the abdomen. Following recent data from the literature, a long-term surveillance is justified after diagnosis of this syndrome, since malignant degeneration may occur within the intestinal polyps as well as in other organs.
Subject(s)
Intussusception/etiology , Jejunal Diseases/etiology , Peutz-Jeghers Syndrome/complications , Child , Diagnostic Imaging , Humans , Intussusception/diagnosis , Intussusception/surgery , Jejunal Diseases/surgery , Male , Peutz-Jeghers Syndrome/diagnosisABSTRACT
Five years ago, a 44 year-old woman presented with an apparently localized cancer of the right breast, initially treated by surgery, adjuvant chemotherapy and radiotherapy. After a 4 year disease-free interval, she developed bi-temporal hemianopsy, due to a suprasellar tumor causing compression of the optic chiasma. The tumor was resected by the transsphenoidal route and histological examination revealed neuroendocrine characteristics described as "argyrophilic breast carcinoma". The exceptional association of this peculiar histology for breast cancer with a rare pattern of recurrence (single pituitary metastasis) is worthwhile reporting.
Subject(s)
Breast Neoplasms/pathology , Pituitary Neoplasms/secondary , Adult , Female , Hemianopsia/etiology , Humans , Nerve Compression Syndromes/complications , Nerve Compression Syndromes/etiology , Optic Chiasm , Pituitary Neoplasms/complications , Pituitary Neoplasms/pathologyABSTRACT
The authors relate a case of a benign tumor (teratoma) sitting in the nasopharynx of a 10-year-old boy. A short review of the literature is presented: speculations over the origins of these tumors, possible diagnosis, treatments... The authors insist on the necessity of realizing some investigations (X-rays, fibro-endoscopy) when regarding a posterior nasal obstruction.
Subject(s)
Nasopharyngeal Neoplasms/diagnosis , Teratoma/diagnosis , Child , Diagnostic Imaging , Humans , Male , Nasopharyngeal Neoplasms/pathology , Nasopharyngeal Neoplasms/surgery , Teratoma/pathology , Teratoma/surgerySubject(s)
Carcinoid Tumor/diagnostic imaging , Cysts/diagnostic imaging , Liver Diseases/diagnostic imaging , Liver Neoplasms/diagnostic imaging , Carcinoid Tumor/pathology , Carcinoid Tumor/secondary , Female , Humans , Ileal Neoplasms/pathology , Liver Neoplasms/pathology , Liver Neoplasms/secondary , Middle Aged , Tomography, X-Ray ComputedSubject(s)
Edema/etiology , Hypothyroidism/complications , Female , Humans , Hypothyroidism/pathology , Middle AgedSubject(s)
Ileal Neoplasms/surgery , Neurilemmoma/surgery , Adult , Humans , Ileal Neoplasms/pathology , Male , Neurilemmoma/pathologySubject(s)
Parotitis/etiology , Tuberculosis, Oral , Tuberculosis , Antitubercular Agents/therapeutic use , Child, Preschool , Humans , Male , Parotid Gland/pathology , Tuberculosis/diagnosis , Tuberculosis/drug therapy , Tuberculosis/pathology , Tuberculosis, Oral/diagnosis , Tuberculosis, Oral/drug therapy , Tuberculosis, Oral/pathologyABSTRACT
The authors report a case of generalised Kaposi sarcoma complicated by pulmonary cryptococcosis and cerebral toxoplasmosis. Clinical features were dominated by the cerebral condition. The infectious pathogenesis could be related to disturbances in immune defences. Ultrastructural study revealed the presence of several types of tumour cells. Endothelial cells formed vascular lumens and contained Weibel-Palade granules and reticulo-tubular inclusions.
Subject(s)
Brain Diseases/etiology , Cryptococcosis/etiology , Lung Diseases, Fungal/etiology , Sarcoma, Kaposi/complications , Toxoplasmosis/etiology , Adult , Humans , Male , Sarcoma, Kaposi/diagnosis , Sarcoma, Kaposi/pathology , Sarcoma, Kaposi/ultrastructureSubject(s)
Bronchial Neoplasms/complications , Glomerulonephritis/etiology , Humans , Male , Middle AgedABSTRACT
In a case of Farber's disease, lysosomal inclusions were shown to contain lamellar, rectilinear, or curvilinear material. In tissue culture, when fibroblasts from the patient were overloaded with ceramides containing nonhydroxylated fatty acids a lysosomal accumulation of small curvilinear structures identical with those observed at autopsy were seen. These inclusions persisted for several weeks after the cells were replaced in a normal culture medium. Normal fibroblasts overloaded in the same experimental conditions showed identical, although less numerous, lysosomal inclusions, which disappeared rapidly in a ceramide-free culture medium. No inclusions were found after overloading normal or pathologic fibroblasts with ceramides containing hydroxylated fatty acids.
Subject(s)
Lipidoses/pathology , Ceramides/metabolism , Culture Techniques , Fatty Acids , Female , Fibroblasts/metabolism , Fibroblasts/ultrastructure , Histiocytes/ultrastructure , Humans , Hydroxylation , Inclusion Bodies/ultrastructure , Infant , Lipidoses/congenital , Lung/pathology , Lysosomes/ultrastructure , Skin , SyndromeABSTRACT
A Grawitz tumour was discovered in a five year old boy. Nephrectomy was performed. The child died four years later in the course of a metastatic generalization. The clinical diagnosis was oriented by haematuria and radiographs which disclosed a calcified tumour at the lower pole of the right kidney. The diagnosis was substantiated by biopsy and morbid anatomy.