1.
Chromosoma
; 129(2): 111-113, 2020 06.
Article
in English
| MEDLINE
| ID: mdl-31273451
ABSTRACT
The recent report of X-chromosome dampening in human preimplantation embryos remains controversial. Subsequently, Sahakyan et al. found evidence of X-chromosome dampening in human naïve pluripotent stem cells (hPSCs) as well. Here, we discuss whether X-dampening reported in hPSCs truly reflects the dampening of X-chromosomes or it is a consequence of the erasure of X-chromosome upregulation.