MODERN ASPECTS OF SUGAR-REDUCING EFFECT OF THICK BEAN EXTRACT BASED ON A TYPE II DIABETES MODEL ON THE BACKGROUND OF OBESITY.

There have been presented the results of the histomorphological research of the effect of the beans' thick extract (BTE) on the state of the pancreas on the model of diabetes mellitus type 2 on the background of obesity in the rats in our research. The simulation of type 2 diabetes on the background of obesity in the animals has led to the development of signs of insulin's inhibition of insulin producing apparatus - some different expressions of dystrophy and degeneration of the ß-cells. The consequence of the hyperfunction has been exhaustion and even death of ß-cells, the development of the diabetic condition. The redistribution of pancreatic islet ß-content of cells has contributed to the increase of the small islands and had a compensatory nature. The treatment of the animals by the BTE has fully prevented an excessive negative impact on revenues of carbohydrates insulin producing apparatus, because it improves the morphological status of ß-cells, reduces the part of small pancreatic islets, almost restores medium and large islets to the level of the «Intact control¼ group. The comparison drug - metformin - has a positive effect on the morphological status of the pancreatic ß-cells, but this effect is obviously not enough for improving or restoring the normal % of distribution of islets.

[Correction of anxiety depressive disorders with tianeptine in patients with heart failure in early period after myocardial infarction].

Aim of the study was clarification of the role of psychological characteristics of personality of patients, relationship between parameters of quality of life and clinical characteristics of the disease and their effect on peculiarities of the course of curative-rehabilitational process as well as clarification of spectrum of clinical activity and safety of tianeptine in anxiety-depressive states in patients with chronic heart failure in early post infarction period. Of 80 patients with anxiety-depressive disorders studied on days 15-30 after onset of disease, 30 received tianeptine (37.5 mg/day) for 3-6 months and 50 comprised control group. Significant reduction of symptoms of anxiety and depression and of cognitive-mnestic functions which occurred in tianeptine treated patients was accompanied with diminished severity of symptoms of heart failure and coronary insufficiency, lowering of index of local myocardial contractility and growth of ejection fraction. All of this resulted in improvement of quality of life of postinfarction patients, shortening of terms of rehabilitational period and allowed the patients to adapt better to surrounding reality.

[The effect of bacterium inoculation on the yield of pure and mixed corn with soya on leached chernozems]. / Bplyv bakteryzatsiï na vrozhainist' chystykh i zmishanykh posiviv kukurudzy i soï na chornozemi vyluhuvanomu.

The use of biopreparations resulted in the increase of green mass within 64-126 c/ha when field experiments were carried out with joint and mixed crops of corn with soya in conditions of the Polyssya leached chernozems. An advantage of 8-23 c/ha was achieved when growing their mixtures. The average crop of green mass for the years of investigations was within 530-894 c/ha. Bacterial fertilizers and soya activate microbiological process of nitrogen cycle, increasing the number of nitrifiers and denitrifiers in the rhizosphere of plants. Thus these factors improve the nitrogen nutrition of cultures in the mixed crops. There is an interaction between plants of corn-soya phytocenosis which has the metabolic-competition character that guarantees better employment of biopreparations and fertilizers, genetic properties of plants and natural resources.

[The carbohydrate components of corn prolamins]. / Izuchenie uglevodnykh komponentov prolaminov kukuruzy.

This work was aimed to study the patterns of zein glycosylation. Zein proteins included 1-3% of sugars. The affinity of different lectins, such as concanavalin A (Con A), Lens culinaris lectin (LCL) and lectins of Arachis hypogaea (PNA), of Triticum vulgaris (WGA), of Dolichos biflorus (DBA), of Glycin max (SBA), of Lotus tetragonolobus (LTA), of Laburnum anagiroides (LAL), of Ricinus communis (RCA), of Phaseolus vulgaris (PHA) was used to analyze the glycosylation sites. All selected lectins interacted with zein proteins. It may serve a basis for determination of mannose, galactose, fucose and aminosugars. Some lectins were bound only by prolamines of some inbred lines, while others were connected with all lines.

[A clinico-dynamic assessment of the structure of autonomic disorders]. / Kliniko-dinamicheskaia otsenka struktury vegetativnykh narushenii.

The initial symptoms of vegetative crisis and the total number of symptoms in the intercrisis period were analyzed in 100 patients with paroxysmal permanent vegetative disorders. The most frequently occurring symptoms were defined and estimated from the standpoint of biological importance on which their higher sensitivity to pathogenic effects is based. The data obtained allow a conclusion about the necessity of differentiated symptomatic therapy.