Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
Eksp Klin Farmakol ; 63(2): 51-3, 2000.
Article in Russian | MEDLINE | ID: mdl-10834095

ABSTRACT

The effect of phencarol, ranitidine, propranolol, atropine, and diethylstilbestrol (known as modulators of the tamoxifen-binding sites in plasma membranes) on the 3H-tamoxifen binding to the plasma membrane fraction of white rat uterine cells was studied by determining the amounts of estradiol and H1- and H2-receptors. The interaction of tamoxifen with various receptors of uterine cells may be significant for evaluation of the tumor activity of this compound.


Subject(s)
Antineoplastic Agents, Hormonal/pharmacokinetics , Tamoxifen/pharmacokinetics , Uterus/metabolism , Animals , Cell Membrane/drug effects , Cell Membrane/metabolism , Drug Interactions , Female , Ligands , Rats , Receptors, Estradiol/drug effects , Receptors, Estradiol/metabolism , Statistics, Nonparametric , Tritium , Uterus/drug effects
SELECTION OF CITATIONS
SEARCH DETAIL
...