[The physicochemical properties of the mixed saliva and parotid secretion of patients with chronic parenchymatous parotitis and of persons who have a history of earlier acute parotitis]. / Fiziko-khimicheskie svoistva smeshannoi sliuny i parotidnogo sekreta u bol'nykh khronicheskim parenkhimatoznym parotitom i u lits, ranee perenesshikh ostryi parotit.

Eighty-five patients with chronic parenchymatous parotitis and 73 convalescents after epidemic or acute nonepidemic parotitis were examined for their secretory function and some physicochemical characteristics of mixed saliva and parotid secretion (secretion rate, pH, viscosity, transparency, electrokinetic properties). A significant reduction of salivary secretion volume and rate were detected, as were pH shift to the acid direction and increased viscosity of both saliva and parotid secretion, reduced transparency and increased electric conductivity in the patients with chronic parenchymatous parotitis, more marked in those with an active course of the disease. Such changes were absent in convalescents after epidemic or acute nonepidemic parotitis. This permits a conclusion that none of these two conditions may be responsible for the development of a chronic inflammation of the parotid gland. The detected changes in physicochemical parameters of the saliva in chronic parenchymatous parotitis supplement the known data on the pathogenesis of this condition and may be used in the diagnosis and prediction of the course and outcome of sialadenitis. The authors emphasize the desirability of therapeutic and prophylactic measures during remissions of chronic parenchymatous parotitis.

[A treatment-prevention combination in the therapy of chronic parenchymatous parotitis in children]. / Lechebno-profilakticheskii kompleks v terapii khronicheskogo parenkhimatoznogo parotita u detei.

A combined treatment-and-prevention complex includes infusion of ol. semeni fructus Rosae into the diseased gland via its duct, peroral administration of retinol acetate and gland electrophoresis with 1% ascorbic acid solution. Up to 10 years follow-up of 118 children confirmed high efficiency of the procedure in 84,75% of the cases. Treatment duration in cases of exacerbations of chronic parotitis was reduced by 7.9 days per year per 1 patient.

[Microbiological research on the secretion of the normal parotid glands and in acute and chronic non-mumps parotitis in children]. / Mikrobiologicheskie issledovaniia sekreta okoloushnykh sliunnykh zhelez v norme, pri ostrom i khronicheskom neépidemicheskom parotite u detei.

The qualitative and quantitative compositions of the microbial flora of the parotid gland were investigated in 42 children with nonepidemic parotiditis. The pathogenic properties of the microbial flora were the most pronounced in acute purulent and purulent necrotic parotiditis as compared to those in aggravation and remission of chronic parotiditis. In children with acute or chronic recurring parotiditis during its aggravation there was observed a significant increase in the number of the coccal organisms in the mixture of saliva and secretion of the parotid gland. Direct relationship between the aggravation activity and the number of the microbes was noted which testified to lowering of the protective functions of the oral cavity tissues. With an account of the presence of microorganisms in the clinically intact salivary glands it was concluded that the microbial factor was secondary in etiology of parotiditis. Quantitative estimation of bacteria in the mixture of saliva and parotid gland secretion is important for antibacterial therapy of the disease which is advisable when 1 ml of secretion of the affected glands contains 10(5) microorganisms. Their antibiotic sensitivity tests are obligatory.